ABSTRACT
BACKGROUND: Several radiological methods for measuring the anteversion of the acetabular component after total hip arthroplasty (THA) exist, and no single standardized method has been established. We evaluated the reliability and accuracy of six widely utilized methods (Liaw et al., Lewinnek et al., Widmer, Hassan et al., Ackland et al., and Woo and Morrey) for measuring anteversion on plain radiographs, using a reference standard in the same definition obtained from the PolyWare programme. METHODS: We reviewed 71 patients who underwent primary unilateral THA. The anteversion of the acetabular component was measured on pelvis AP radiographs using five different methods (Liaw et al., Lewinnek et al., Widmer, Hassan et al., and Ackland et al.) and on cross-table lateral radiographs using the method of Woo and Morrey. The values obtained using the PolyWare programme, which determines the anteversion of the acetabular component by edge detection, were regarded as the reference standard. RESULTS: Intra- and inter-observer reliabilities were excellent for all methods using plain radiographs, including the PolyWare programme. The method of Liaw et al. obtained values similar to those obtained using the PolyWare programme and was thus considered accurate (P = 0.447). However, values obtained using the other five methods significantly differed from those obtained using the PolyWare programme and were thus considered less accurate (P < 0.001, P < 0.001, P < 0.001, P = 0.007, and P < 0.001, respectively). CONCLUSION: The method of Liaw et al. is more accurate than other methods using plain radiographs for the measurement of the anteversion of the acetabular component after THA, with reference to the anteversion obtained from the PolyWare programme.
Subject(s)
Acetabulum/diagnostic imaging , Arthroplasty, Replacement, Hip/methods , Bone Anteversion/diagnostic imaging , Acetabulum/pathology , Adult , Aged , Arthroplasty, Replacement, Hip/adverse effects , Arthroplasty, Replacement, Hip/instrumentation , Bone Anteversion/etiology , Bone Anteversion/pathology , Female , Hip Prosthesis , Humans , Male , Middle Aged , Observer Variation , Radiographic Image Interpretation, Computer-Assisted/methods , Radiography , Reproducibility of Results , Young AdultABSTRACT
OBJECTIVE: To examine the association between development of degenerative lumbar scoliosis (DLS) and sex hormones. METHODS: We investigated the association between DLS and estrogen receptor alpha (ERα) gene polymorphisms in 184 patients with a diagnosis of DLS, by determining the presences of the Pvu II and Xba I polymorphisms, measuring bone mineral densities at the lumbar spine (LSBMD) and femoral neck (FNBMD), and by investigating biochemical markers of bone turnover and comparing these results with those of 220 healthy normal controls. RESULTS: Genotype frequencies in DLS patients and controls revealed a significant difference for the Pvu II polymorphism only (p = 0.0287). No significant difference was found between the DLS and control groups with respect to the Xba I polymorphism, bone mineral density (BMD), or biochemical markers. Furthermore, no significant association was observed between the Pvu II polymorphism and BMD, lumbar scoliosis, lateral listhesis, or biochemical markers in patients with DLS. CONCLUSION: These results suggest that the ERα Pvu II polymorphism influences the prevalence of DLS.
Subject(s)
Estrogen Receptor alpha/genetics , Intervertebral Disc Degeneration/genetics , Polymorphism, Genetic/genetics , Scoliosis/genetics , Absorptiometry, Photon , Aged , Biomarkers , Bone Density/genetics , DNA-Cytosine Methylases/genetics , Female , Gene Frequency , Genotype , Humans , Intervertebral Disc Degeneration/epidemiology , Male , Middle Aged , Polymorphism, Single Nucleotide/genetics , Prevalence , Scoliosis/epidemiology , Site-Specific DNA-Methyltransferase (Adenine-Specific)/geneticsABSTRACT
Bilateral pathologic femoral neck fractures caused by nonHodgkin's lymphoma occurred consecutively in a 66-year-old man. Spontaneous bony stabilization after initial extensive bone resorption around the femoral stems after hybrid total hip arthroplasties was observed. This is the first well-documented report on bone change around the femoral stems after bilateral total hip arthroplasties in pathologic femoral neck fractures caused by nonHodgkin's lymphoma.