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1.
Arch Soc Esp Oftalmol (Engl Ed) ; 97(4): 219-223, 2022 Apr.
Article in English | MEDLINE | ID: mdl-35523468

ABSTRACT

Full-thickness macular hole is a rare complication of macular telangiectasia type 2, and its treatment is still controversial. A patient with a full-thickness macular hole secondary to macular telangiectasia type 2 underwent vitreoretinal surgery with a plasma rich in growth factors membrane in the macular hole. At the sixth month of follow-up, anatomical and functional improvements were achieved, with no adverse effects. Plasma rich in growth factors is a new option, with advantages due to its biological properties that achieves good results in terms of safety and effectiveness in the surgical treatment of macular hole.


Subject(s)
Retinal Perforations , Retinal Telangiectasis , Humans , Retinal Perforations/etiology , Retinal Perforations/surgery , Retinal Telangiectasis/complications , Retinal Telangiectasis/therapy , Vitrectomy/methods
2.
Arch. Soc. Esp. Oftalmol ; 97(4): 219-223, abr. 2022. ilus
Article in Spanish | IBECS | ID: ibc-208842

ABSTRACT

El agujero macular de espesor total es una complicación rara de la telangiectasia macular tipo 2, y su tratamiento es aún controvertido. Una paciente con esta entidad fue llevada a cirugía vitreorretiniana con aplicación de membrana de plasma rico en factores de crecimiento sobre el agujero macular. Al sexto mes de cirugía se logró mejoría anatómica y funcional, sin efectos adversos asociados. El plasma rico en factores de crecimiento es una alternativa nueva en el tratamiento quirúrgico del agujero macular atípico y/o persistente, que logra buenos resultados en términos de seguridad efectividad, debido a sus propiedades biológicas (AU)


Full-thickness macular hole is a rare complication of macular telangiectasia type 2, and its treatment is still controversial. A patient with a full-thickness macular hole secondary to macular telangiectasia type 2 underwent vitreoretinal surgery with a plasma rich in growth factors membrane in the macular hole. At the sixth month of follow-up, anatomical and functional improvements were achieved, with no adverse effects. Plasma rich in growth factors is a new option, with advantages due to its biological properties that achieves good results in terms of safety and effectiveness in the surgical treatment of macular holey (AU)


Subject(s)
Humans , Female , Aged , Retinal Perforations/etiology , Retinal Perforations/surgery , Retinal Telangiectasis/complications , Vitreoretinal Surgery/methods , Transforming Growth Factors/administration & dosage , Plasma , Treatment Outcome
3.
Food Chem ; 354: 129490, 2021 Aug 30.
Article in English | MEDLINE | ID: mdl-33774531

ABSTRACT

Physico-chemical and sensory analysis of Iberian chorizo manufactured from three commercial categories raw material compiled in the current Spanish Iberian Quality standard (Black, Red; 100% Iberian and 50% Iberian × Duroc pigs, respectively, under Montanera, and White; 50% Iberian × Duroc pigs commercially fed) and packed under vacuum and modified atmosphere (MAP) were carried out, in order to address the influence of the genotype and animal production system and packaging on quality parameters, as well as the stability of these throughout long-term storage. Montanera categories showed higher values of γ-tocopherol, mono- and poly-unsaturated fatty acids, greater scores of flavour and taste and higher lipid oxidation during the whole storage. MAP preserved better colour, especially redness and lipid oxidative status. Iberian chorizo could attain a differentiated quality because of physico-chemical and sensorial characteristics derived from the Montanera that would be adequate preserved in both vacuum and MAP throughout long-term storage.


Subject(s)
Food Packaging/methods , Meat Products/analysis , Animals , Atmosphere , Chromatography, High Pressure Liquid , Color , Fatty Acids, Unsaturated/analysis , Lipid Peroxidation , Refrigeration , Sodium Chloride/chemistry , Swine , Taste/physiology , Vacuum , alpha-Tocopherol/analysis , gamma-Tocopherol/analysis
4.
Article in English, Spanish | MEDLINE | ID: mdl-33627242

ABSTRACT

Full-thickness macular hole is a rare complication of macular telangiectasia type 2, and its treatment is still controversial. A patient with a full-thickness macular hole secondary to macular telangiectasia type 2 underwent vitreoretinal surgery with a plasma rich in growth factors membrane in the macular hole. At the sixth month of follow-up, anatomical and functional improvements were achieved, with no adverse effects. Plasma rich in growth factors is a new option, with advantages due to its biological properties that achieves good results in terms of safety and effectiveness in the surgical treatment of macular hole.

5.
Arch Soc Esp Oftalmol (Engl Ed) ; 94(1): 4-11, 2019 Jan.
Article in English, Spanish | MEDLINE | ID: mdl-30270037

ABSTRACT

BACKGROUND AND OBJECTIVE: In view of the increasing bacterial resistance to antibiotics, it is necessary to determine it locally in order to serve as a guide in clinical management. The purpose of this study was to characterise the pattern of antibiotic sensitivity in cases of eye infections in a third level ophthalmological institution in Floridablanca (Colombia). MATERIALS AND METHODS: An observational cross-sectional study in which an analysis was made of the culture and antibiogram reports of specimens taken from cases of conjunctivitis, infectious keratitis, and endophthalmitis between January 2013 and June 2016. RESULTS: A total of 833 specimens were positive for bacteria. Considering both gram-positive and gram-negative microorganisms gentamicin, tobramycin, and ciprofloxacin showed high resistance rates (64.4%, 40.3%, and 29.1%, respectively). Moxifloxacin, vancomycin, imipenem, and gatifloxacin showed low percentages of resistance: 2.6%, 2.1%, 0.6%, and 0.4%, respectively. When comparing the results with previous studies in our institution, there was a decrease in sensitivity to the fourth-generation quinolones and imipenem, especially within the gram-negative ones. CONCLUSION: Fourth generation quinolones, imipenem and vancomycin continue to have a low in vitro resistance to bacteria that cause eye infections. However, there was a tendency to an increase in the resistance of gram-negative bacteria. Measures should be taken to try to control this phenomenon, and consider possible antimicrobial therapy alternatives to infections caused by these microorganisms.


Subject(s)
Conjunctivitis, Bacterial/drug therapy , Drug Resistance, Bacterial , Endophthalmitis/drug therapy , Keratitis/drug therapy , Anti-Bacterial Agents/therapeutic use , Colombia , Conjunctivitis, Bacterial/microbiology , Cross-Sectional Studies , Endophthalmitis/microbiology , Gram-Negative Bacterial Infections/drug therapy , Gram-Positive Bacterial Infections/drug therapy , Humans , Keratitis/microbiology , Microbial Sensitivity Tests
6.
Arch Soc Esp Oftalmol (Engl Ed) ; 93(12): 617-620, 2018 Dec.
Article in English, Spanish | MEDLINE | ID: mdl-30001848

ABSTRACT

OBJECTIVE/METHODS: The aim of this study is to describe the use of botulinum toxin to increase tear retention in patients with dry eye, using the description of 2 cases. RESULTS: Patients with moderate to severe dry eye that were given an injection of type A botulinum toxin in the Horner's muscle. The results at one month and 3 months are reported. An assessment was made of the subjective perception of the patient as regards any improvement, as well as taking into account, the Ocular Surface Disease Index, superficial punctate keratitis, and the time of the tear rupture and tear meniscus. A significant improvement was observed in the subjective perception of the patient, the Ocular Surface Disease Index, superficial punctate keratitis, and the time of the tear rupture and tear meniscus at one month after treatment, and the good results still being maintained at the third month. There were no adverse events. DISCUSSION: The use of type A botulinum toxin can be considered as an alternative to increase tear retention in moderate to severe dry eye, with a good response during the first month, with an acceptable response still being maintained at the third month. Given the temporary effect of the drug, further treatments would be required.


Subject(s)
Botulinum Toxins, Type A/administration & dosage , Dry Eye Syndromes/drug therapy , Neuromuscular Agents/administration & dosage , Aged , Botulinum Toxins, Type A/therapeutic use , Eyelids , Female , Humans , Injections, Intramuscular , Lubricant Eye Drops/therapeutic use , Middle Aged , Muscle, Skeletal , Neuromuscular Agents/therapeutic use
7.
Arch Soc Esp Oftalmol ; 92(7): 307-325, 2017 Jul.
Article in English, Spanish | MEDLINE | ID: mdl-28162831

ABSTRACT

Experimental studies in animals, as well as observational and intervention studies in humans, seem to support the premise that the development of juvenile myopia is promoted by a combination of the effect of genetic and environmental factors, with a complex interaction between them. The very rapid increase in myopia rates in some parts of the world, such as Southeast Asia, supports a significant environmental effect. Several lines of evidence suggest that humans might respond to various external factors, such as increased activity in near vision, increased educational pressure, decreased exposure to sunlight outdoors, dietary changes (including increased intake of carbohydrates), as well as low light levels indoors. All these factors could be associated with a higher prevalence of myopia.


Subject(s)
Gene-Environment Interaction , Myopia/etiology , Adult , Child , Diet , Educational Status , Humans , Insulin Resistance , Life Style , Lighting , Risk Factors
9.
Plant Mol Biol ; 32(3): 453-60, 1996 Nov.
Article in English | MEDLINE | ID: mdl-8980494

ABSTRACT

We have isolated a genomic clone encoding tomato TAS14, a dehydrin that accumulates in response to mannitol, NaCl or abscisic acid (ABA) treatment. A fragment of tas14 gene containing the region from -2591 to +162 fused to beta-glucuronidase gene drives ABA- and osmotic stress-induced GUS expression in transgenic tobacco. Histochemical analysis of salt-, mannitol- and ABA-treated plants showed GUS activity mainly localized to vascular tissues, outer cortex and adventitious root meristems, coinciding with the previously observed distribution of TAS14 protein in salt-stressed tomato plants. In addition, GUS activity was also observed in guard cells, trichomes and leaf axils. Developmentally regulated gus expression was studied in unstressed plants and found to occur not only in embryos, but also in flowers and pollen. Tas14 expression in floral organs was confirmed by northern blots of tomato flowers.


Subject(s)
Gene Expression Regulation, Plant/physiology , Plant Proteins/genetics , Solanum lycopersicum/genetics , Abscisic Acid/pharmacology , Cloning, Molecular , Gene Expression Regulation, Plant/drug effects , Genes, Reporter/genetics , Glucuronidase/genetics , Solanum lycopersicum/growth & development , Mannitol/pharmacology , Molecular Sequence Data , Osmotic Pressure , Plants, Genetically Modified , Plants, Toxic , Promoter Regions, Genetic/genetics , RNA, Messenger/analysis , RNA, Plant/analysis , Sequence Analysis, DNA , Sodium Chloride/pharmacology , Nicotiana/genetics , Nicotiana/growth & development
11.
J Clin Lab Immunol ; 11(2): 95-100, 1983 Jun.
Article in English | MEDLINE | ID: mdl-6876145

ABSTRACT

The effect of various concentrations of Adriamycin alone and Adriamycin plus vitamin E on human polymorphonuclear leukocyte (PMNL) function was determined. Aliquots of PMNLs were incubated at 37 degrees C with saline or vitamin E and then exposed to Adriamycin. A significant decrease in 1-14C glucose utilization and oxygen consumption by zymosan stimulated PMNLs occurred when PMNLs were incubated with 1, 10, 20, 1000 and 200 micrograms/ml concentrations of Adriamycin. Preincubation of the PMNLs with vitamin E afforded partial protection at lower concentrations. The total uptake at 3, 10 and 20 min of methyl 3H thymidine labeled S. aureus by control PMNL was significantly greater than by PMNLs exposed for 60 min to 100 micrograms/ml of Adriamycin. Intracellular Adriamycin concentrations increased in a dose dependent fashion. Viability of cells before and after incubation was 95%. Adriamycin inhibited oxidative metabolic and functional activity of PMNLs in a dose related manner. Preincubation of PMNLs with vitamin E partially protected them from the effects of Adriamycin.


Subject(s)
Doxorubicin/pharmacology , Neutrophils/physiology , Vitamin E/pharmacology , Chromatography, High Pressure Liquid , Glucose/metabolism , Humans , Neutrophils/immunology , Phagocytosis , Staphylococcus aureus/metabolism
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