ABSTRACT
A 61-year-old woman who was negative for type 1 human immunodeficiency virus developed vertebral osteomyelitis and skin lesions due to sepsis by Staphylococcus aureus. Microscopic examination of the skin showed alcohol-resistant acid-fast bacilli. A polymerase chain reaction (PCR) assay for Mycobacterium tuberculosis was positive for skin and spinal samples, although the cultures were negative. The diagnosis of M. tuberculosis infection is difficult, particularly when the disease is extrapulmonary. Rapid diagnostic tests that use PCR identify the DNA of the bacillus with greater sensitivity than microscopic examination and can give results within 24 hours of receipt of a sample. We analyze the utility of PCR for diagnosing extrapulmonary tuberculosis.
Subject(s)
Shock, Septic/etiology , Tuberculosis, Cutaneous/complications , Tuberculosis, Spinal/complications , Female , Humans , Middle Aged , Tuberculosis, Cutaneous/diagnosis , Tuberculosis, Spinal/diagnosisSubject(s)
AIDS-Related Opportunistic Infections/diagnosis , Cytomegalovirus Infections/diagnosis , HIV Infections/complications , Polyradiculopathy/etiology , Tuberculosis, Meningeal/etiology , AIDS-Related Opportunistic Infections/drug therapy , Adult , Antitubercular Agents/therapeutic use , Antiviral Agents/therapeutic use , Brain/diagnostic imaging , Cytomegalovirus Infections/drug therapy , Diagnosis, Differential , Foscarnet/therapeutic use , HIV Infections/drug therapy , Humans , Lumbosacral Region , Magnetic Resonance Imaging , Male , Polyradiculopathy/diagnosis , Polyradiculopathy/drug therapy , Reverse Transcriptase Inhibitors/therapeutic use , Tomography, X-Ray Computed , Tuberculosis, Lymph Node/drug therapy , Tuberculosis, Lymph Node/etiology , Tuberculosis, Meningeal/diagnosis , Tuberculosis, Meningeal/drug therapySubject(s)
Ascites/etiology , Corynebacterium Infections , Corynebacterium/isolation & purification , Anti-Bacterial Agents/therapeutic use , Ascitic Fluid/microbiology , Corynebacterium Infections/drug therapy , Corynebacterium Infections/microbiology , Humans , Neutrophils , Peritonitis/etiology , Peritonitis/microbiologyABSTRACT
Recently, the syndrome of remitting seronegative symmetrical synovitis with pitting edema (RS3PE), has been proposed. The RS3PE syndrome has an acute onset, does not produce bony erosions, with a predilection for elderly patients and an excellent prognosis. This condition distinguishing if from rheumatoid arthritis and polymyalgia rheumatica. The purpose is to call attention to a benign forms of arthritis in aging patients. We report two cases of RS3PE syndrome.
