ABSTRACT
Mucormycosis is an unusual fungal infection that usually affects immunosuppressed patients. Small outbreaks of mucormycosis have been previously reported. We present two clinical cases of fatal rhinocerebral mucormycosis with a close temporal relationship between them and a possible nosocomial transmission: case 1 was a 75-year-old male with diabetes and COPD, treated with antibiotics and systemic corticosteroids, who developed rhinocerebral mucormycosis. Case 2 was an 88-year-old woman who was treated with systemic antibiotics and corticosteroids and developed the same infection after insertion of a nasogastric tube. Both patients concurred at the same time in our hospital, and healthcare staff was common to both of them. These cases, along with previously reported cases, highlight that, although infrequent, transmission of the fungus in the hospital environment is a real possibility that should be taken into account in order to initiate contact and air isolation precautions that could avoid nosocomial transmission of this infection.
Subject(s)
Cross Infection/diagnosis , Meningitis, Fungal/diagnosis , Meningitis, Fungal/pathology , Mucormycosis/diagnosis , Opportunistic Infections/diagnosis , Rhinitis/complications , Rhinitis/diagnosis , Adrenal Cortex Hormones/administration & dosage , Aged , Aged, 80 and over , Anti-Bacterial Agents/administration & dosage , Cross Infection/microbiology , Cross Infection/pathology , Diabetes Complications , Fatal Outcome , Female , Humans , Immunocompromised Host , Male , Meningitis, Fungal/microbiology , Mucormycosis/microbiology , Mucormycosis/pathology , Opportunistic Infections/microbiology , Opportunistic Infections/pathology , Pulmonary Disease, Chronic Obstructive/complications , Rhinitis/microbiology , Rhinitis/pathology , Rhizopus/isolation & purificationABSTRACT
No disponible
Subject(s)
Humans , Female , Aged, 80 and over , Bronchography/instrumentation , Bronchography/methods , Incidental Findings , Deglutition Disorders/complications , Deglutition Disorders/prevention & control , Malabsorption Syndromes/complications , Bronchi/pathology , Bronchi , Stroke/complications , Stroke/epidemiology , Quality of LifeSubject(s)
Bronchi/diagnostic imaging , Contrast Media , Deglutition Disorders/complications , Respiratory Aspiration of Gastric Contents/diagnostic imaging , Aged, 80 and over , Cognition Disorders/complications , Female , Frail Elderly , Humans , Infarction, Middle Cerebral Artery/complications , Intestine, Small/diagnostic imaging , Multimorbidity , Respiratory Aspiration of Gastric Contents/etiology , Trachea/diagnostic imagingABSTRACT
Las vasculitis sistémicas son un grupo muy heterogéneo de enfermedades de diversas etiologías y manifestaciones. En general, la clínica se deriva de la isquemia producida por la inflamación vascular de la cual depende el órgano afecto. Se clasifican según el consenso de la conferencia de Chapel Hill. Se pueden presentar con relativa frecuencia como manifestaciones otorrinolaringológicas tanto en su debut como a lo largo de su evolución, por lo tanto deben incluirse en el diagnóstico diferencial del especialista en otorrinolaringología en pacientes de difícil control o presentación atípica de manifestaciones ORL. Es nuestra intención revisar la clínica otorrinolaringológica más frecuente en cada una de estas enfermedades(AU)
Systemic vasculitis is a heterogeneous group of diseases of various aetiologies and manifestations. In general, the clinical results derive from ischemia caused by vascular inflammation, which depends on the organ affected. Such vasculitis cases are classified according to the classification of the Chapel Hill conference. They can present with relative frequency as ENT manifestations in both their debut and throughout their evolution. Consequently, the ENT specialist should include them in the differential diagnosis in patients with ENT manifestations that are difficult to control or of atypical presentation. Our objective was to review the most common ENT clinical signs and symptoms in each of these diseases(AU)
Subject(s)
Humans , Male , Female , Systemic Vasculitis/complications , Systemic Vasculitis/diagnosis , Granulomatosis with Polyangiitis/complications , Granulomatosis with Polyangiitis/diagnosis , Giant Cell Arteritis/complications , Takayasu Arteritis/complications , Diagnosis, Differential , Systemic Vasculitis/etiology , Systemic Vasculitis/physiopathology , Inflammation/complications , Inflammation/etiology , Churg-Strauss Syndrome/complications , Cogan Syndrome/complicationsABSTRACT
Systemic vasculitis is a heterogeneous group of diseases of various aetiologies and manifestations. In general, the clinical results derive from ischemia caused by vascular inflammation, which depends on the organ affected. Such vasculitis cases are classified according to the classification of the Chapel Hill conference. They can present with relative frequency as ENT manifestations in both their debut and throughout their evolution. Consequently, the ENT specialist should include them in the differential diagnosis in patients with ENT manifestations that are difficult to control or of atypical presentation. Our objective was to review the most common ENT clinical signs and symptoms in each of these diseases.
