ABSTRACT
INTRODUCTION: Parkinson's disease (PD) is a neurodegenerative disorder in which motor symptoms are initially predominant; however, as the disease progresses, cognitive deterioration becomes more evident. Tests designed to detect cognitive impairment are therefore needed. AIMS: The aim of the study was to assess the cognitive status of a population of patients with PD by means of the Mini Mental Parkinson test (MMP). PATIENTS AND METHODS: In 110 patients with idiopathic PD, with a mean age of 66.4 +/- 10.2 years and an average history of 8.8 +/- 5.8 years of the disease, the mean severity of the disease as measured by the unified PD rating scale (UPDRS-III) was 26.2 +/- 12.9. RESULTS: There were 20 (18.2%) subjects with dementia according to DSM-IV criteria, with a score of 20.4 +/- 6.4 on the MMP. Of the 90 patients who did not have dementia, 47 cases displayed cognitive impairment, without the presence of disorders affecting their activities of daily living, who scored 25.3 +/- 4.7 points on the MMP, and 43 cases did not show any kind of cognitive impairment, with 28.0 +/- 3.3 points on the MMP; these differences were statistically significant p < 0.001. Results according to age brackets showed a decrease in MMP with age and more especially so concerning memory functioning. As to severity, there is a cognitive decline, in particular with regard to memory, orientation and abstraction. CONCLUSIONS: Cognitive capacity is seen to decline with age and the severity of the disease.
Subject(s)
Cognition Disorders/diagnosis , Cognition Disorders/etiology , Intelligence Tests , Parkinson Disease/complications , Aged , Female , Humans , MaleABSTRACT
Introducción. La enfermedad de Parkinson (EP) es un cuadro neurodegenerativo en el que inicialmente predominan los síntomas motores; sin embargo, con la progresión de la enfermedad se evidencian deterioros cognitivos. Es necesario usar test dirigidos a la detección del deterioro cognitivo. Objetivos. Evaluar el estado cognitivo de una población de pacientes con EP mediante la administración del test minimental Parkinson (MMP). Pacientes y métodos. En 110 pacientes con EP idiopática, con una edad media de 66,4 10,2 años y un tiempo medio de evolución de la enfermedad de 8,8 5,8 años, la gravedad media de la enfermedad con la escala unificada para la valoración de la EP (UPDRS-III) es 26,2 12,9. Resultados. Los sujetos que presentan demencia según los criterios del DSM-IV son 20 (18,2%), con una puntuación de 20,4 6,4 en el MMP. De los 90 pacientes que no presentan demencia, 47 casos muestran deterioro cognitivo, sin presencia de afectación de las actividades de la vida diaria, con 25,3 4,7 puntos en el MMP, y aquellos que no presentan ninguna forma de déficit cognitivo son 43 casos, con 28,0 3,3 puntos en el MMP, diferencias estadísticamente significativas p 0,001. Los resultados según el intervalo de edad demuestran una disminución del MMP con la edad y, especialmente, en la función memoria. En relación con la gravedad, existe un declive cognitivo especialmente en las funciones orientación, memoria y abstracción. Conclusiones. Se evidencia una disminución de la capacidad cognitiva con relación a la edad y la gravedad de la enfermedad
Introduction. Parkinsons disease (PD) is a neurodegenerative disorder in which motor symptoms are initially predominant; however, as the disease progresses, cognitive deterioration becomes more evident. Tests designed to detect cognitive impairment are therefore needed. Aims. The aim of the study was to assess the cognitive status of a population of patients with PD by means of the Mini Mental Parkinson test (MMP). Patients and methods. In 110 patients with idiopathic PD, with a mean age of 66.4 ± 10.2 years and an average history of 8.8 ± 5.8 years of the disease, the mean severity of the disease as measured by the unified PD rating scale (UPDRS-III) was 26.2 ± 12.9. Results. There were 20 (18.2%) subjects with dementia according to DSM-IV criteria, with a score of 20.4 ± 6.4 on the MMP. Of the 90 patients who did not have dementia, 47 cases displayed cognitive impairment, without the presence of disorders affecting their activities of daily living, who scored 25.3 ± 4.7 points on the MMP, and 43 cases did not show any kind of cognitive impairment, with 28.0 ± 3.3 points on the MMP; these differences were statistically significant p < 0.001. Results according to age brackets showed a decrease in MMP with age and more especially so concerning memory functioning. As to severity, there is a cognitive decline, in particular with regard to memory, orientation and abstraction. Conclusions. Cognitive capacity is seen to decline with age and the severity of the disease
