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1.
Bone Joint J ; 96-B(2): 263-9, 2014 Feb.
Article in English | MEDLINE | ID: mdl-24493195

ABSTRACT

We reviewed the outcome of 69 uncemented, custom-made, distal femoral endoprosthetic replacements performed in 69 patients between 1994 and 2006. There were 31 women and 38 men with a mean age at implantation of 16.5 years (5 to 37). All procedures were performed for primary malignant bone tumours of the distal femur. At a mean follow-up of 124.2 months (4 to 212), 53 patients were alive, with one patient lost to follow-up. All nine implants (13.0%) were revised due to aseptic loosening at a mean of 52 months (8 to 91); three implants (4.3%) were revised due to fracture of the shaft of the prosthesis and three patients (4.3%) had a peri-prosthetic fracture. Bone remodelling associated with periosteal cortical thinning adjacent to the uncemented intramedullary stem was seen in 24 patients but this did not predispose to failure. All aseptically loose implants in this series were diagnosed to be loose within the first five years. The results from this study suggest that custom-made uncemented distal femur replacements have a higher rate of aseptic loosening compared to published results for this design when used with cemented fixation. Loosening of uncemented replacements occurs early indicating that initial fixation of the implant is crucial.


Subject(s)
Coated Materials, Biocompatible , Durapatite , Femoral Neoplasms/surgery , Forecasting , Prosthesis Implantation/methods , Adolescent , Adult , Bone Cements , Child , Child, Preschool , Female , Femoral Neoplasms/diagnostic imaging , Femoral Neoplasms/mortality , Follow-Up Studies , Humans , Male , Prosthesis Design , Radiography , Retrospective Studies , Survival Rate/trends , Treatment Outcome , United Kingdom/epidemiology , Young Adult
2.
J Bone Joint Surg Br ; 92(12): 1685-9, 2010 Dec.
Article in English | MEDLINE | ID: mdl-21119175

ABSTRACT

We have reviewed five adult patients treated with endoprosthetic reconstruction of the proximal radius following resection of non-traumatic lesions. The patients had a mean age of 33.4 years (20 to 60) at the time of surgery and the mean follow-up was 7.6 years (0.8 to 16). Following surgery, all elbows were clinically stable and there was 100% survivorship of the prosthesis. Evaluation of function was assessed clinically and by the Mayo Elbow Performance Score, achieving a mean of 86% (70 to 100). Results at medium-term follow-up are encouraging with regards to elbow stability, implant survivorship and functional outcome.


Subject(s)
Bone Neoplasms/surgery , Prostheses and Implants , Radius/surgery , Adult , Bone Neoplasms/diagnostic imaging , Elbow Joint/physiopathology , Female , Follow-Up Studies , Humans , Male , Middle Aged , Prosthesis Design , Prosthesis Implantation/adverse effects , Prosthesis Implantation/methods , Radiography , Radius/diagnostic imaging , Range of Motion, Articular , Titanium , Treatment Outcome , Wrist Joint/physiopathology , Young Adult
3.
J Bone Joint Surg Br ; 92(2): 262-6, 2010 Feb.
Article in English | MEDLINE | ID: mdl-20130320

ABSTRACT

Elastofibroma dorsi is an uncommon, benign, slow-growing soft-tissue tumour of uncertain aetiology. It classically presents as an ill-defined mass at the inferior pole of the scapula with symptoms which include swelling, discomfort, snapping, stiffness and occasionally pain. We report the symptoms, function and outcome after treatment of 21 elastofibromas in 15 patients. All were diagnosed by MRI and early in the series four also underwent CT-guided biopsy to confirm the diagnosis. In all, 18 tumours were excised and three were observed. After excision, the mean visual analogue score for pain decreased from 4.6 (0 to 10) pre-operatively to 2.4 (0 to 8) post-operatively (p = 0.04). The mean shoulder function, at a mean follow-up of 4.2 years (3 months to 16 years), was 78.1% (30 to 100) using the Stanmore percentage of normal shoulder assessment scoring system. The mean range of forward flexion improved from 135 degrees (70 degrees to 180 degrees ) to 166 degrees (100 degrees to 180 degrees ) after excision (p = 0.005). In four patients a post-operative haematoma formed; one required evacuation. Three patients developed a post-operative seroma requiring needle aspiration and one developed a superficial infection which was treated with antibiotics. Our findings support previous reports suggesting that a pre-operative tissue diagnosis is not necessary in most cases since the lesion can be confidently diagnosed by MRI, when interpreted in the light of appropriate clinical findings. Surgical excision in symptomatic patients, is helpful. It has been suggested that elastofibroma is caused by a local tissue reaction and is not a true neoplastic process. A strong association has been noted between elastofibroma and repetitive use of the shoulder, which is supported by our findings.


Subject(s)
Fibroma/diagnosis , Soft Tissue Neoplasms/diagnosis , Adult , Aged , Female , Fibroma/surgery , Follow-Up Studies , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Postoperative Complications , Range of Motion, Articular , Scapula , Shoulder Joint/physiopathology , Soft Tissue Neoplasms/surgery , Tomography, X-Ray Computed , Treatment Outcome
4.
Case Rep Med ; 2009: 520126, 2009.
Article in English | MEDLINE | ID: mdl-19902012

ABSTRACT

Myolipoma is a rare, benign, lipomatous tumour which most commonly occurs in the retroperitoneum, pelvis, and abdomen. A 4-year-old boy presented with a painless enlarging mass in the left paraspinal region. Magnetic Resonance Imaging (MRI) revealed a soft tissue lesion with high fat content and areas of calcification. Excision and histopathological analysis revealed a tumour composed of lobules of mature adipose tissue and broad septa of well-differentiated smooth muscle tissue. The smooth muscle nature of the nonfatty component was demonstrated by a diffuse and strong immunoreactivity for smooth muscle actin and desmin. The mass was reported as a myolipoma. The patient made an unremarkable recovery from surgery and remains healthy with no signs of recurrence at seven years. This paper represents the youngest patient diagnosed with this rare soft tissue tumour which is normally confined to the adult population. A newly reported site of the tumour is also highlighted.

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