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1.
Vet Rec ; 181(20): 540, 2017 Nov 18.
Article in English | MEDLINE | ID: mdl-28893970

ABSTRACT

Infection by Cryptosporidium baileyi was first confirmed in red grouse in northern England in 2010 and within three years spread to 48 per cent of moors. These form the last English stronghold for the rarer black grouse, and given the rapid spread of respiratory cryptosporidiosis among red grouse, concern has been expressed about possible infection. In 2010, the authors started screening black grouse for cryptosporidiosis in (1) dead birds taken for postmortem examination, (2) sample birds caught at night and (3) an observational study of birds attending leks. Between 2011 and 2016, five males were sent for postmortem examination, of which three had suspected cryptosporidiosis. No disease was found in one; the second had extensive, subacute to chronic sinusitis; and the third had severe sinusitis and unilateral conjunctivitis. PCR analysis detected cryptosporidial DNA in the third bird only; however, the parasite was not seen in stained preparations or on histopathology. No cryptosporidiosis clinical signs were observed in 69 birds caught at night or in 170 birds attending leks. The authors have no conclusive evidence that cryptosporidiosis is causing sinusitis in black grouse. However, a single positive cryptosporidia PCR result from an affected bird does raise the possibility that they may be infected with the parasite.


Subject(s)
Cryptosporidiosis/diagnosis , Cryptosporidium/isolation & purification , Galliformes/parasitology , Respiratory Tract Diseases/veterinary , Animals , Cryptosporidiosis/epidemiology , England/epidemiology , Male , Polymerase Chain Reaction/veterinary , Respiratory Tract Diseases/diagnosis , Respiratory Tract Diseases/epidemiology
2.
Int Wound J ; 12(4): 402-7, 2015 Aug.
Article in English | MEDLINE | ID: mdl-23834451

ABSTRACT

Debridement is integral to wound bed preparation by removing devitalised tissue, foreign material, senescent cells, phenotypically abnormal/dysfunctional cells (cellular burden) and bacteria sequestrum (biofilm). While the body of evidence to substantiate the benefits of debridement is growing, little is known about the cost-effectiveness of each debridement method. The purpose of this analysis was to compare cost-effectiveness of various debridement methods and clinical outcomes to help inform clinicians and policy makers of the cost-effectiveness associated with the various types of therapies and the impact they can have on the Canadian health care system. Results indicated that sharp debridement was the most cost-effective followed by enzymatic debridement method.


Subject(s)
Cost-Benefit Analysis/statistics & numerical data , Debridement/economics , Debridement/methods , Wounds and Injuries/therapy , Canada , Humans , Wound Healing
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