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Eksp Onkol ; 8(4): 70-2, 1986.
Article in Russian | MEDLINE | ID: mdl-3757890

ABSTRACT

Japan cucumaria possesses an inhibitory action on the solid Ehrlich adenocarcinoma. The optimum dose, 15000 mg/kg, is established which provides a 46.49% of the growth inhibiting. The delay of the malignant process development is followed by normalization on phospholipid metabolism in the liver of tumour-bearing mice: the contents of phosphatidylcholine reached the normal level, the contents of sphingomyelin decreased, a portion of lysophosphatidylcholine and lysophosphatidylethanolamine was considerably reduced. The results obtained show that certain doses of cucumaria improve metabolic processes in the liver.


Subject(s)
Antineoplastic Agents/therapeutic use , Carcinoma, Ehrlich Tumor/drug therapy , Echinodermata , Liver/metabolism , Phospholipids/metabolism , Sea Cucumbers , Animals , Carcinoma, Ehrlich Tumor/metabolism , Mice
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