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BMJ Case Rep ; 20132013 Jan 23.
Article in English | MEDLINE | ID: mdl-23349175

ABSTRACT

Epidermolysis bullosa (EB) constitutes a group of phenotypically diverse genodermatoses, which manifests with blistering and erosions of the skin and mucous membranes as the unifying diagnostic feature. It is an acquired disease or inherited as either autosomal-dominant or recessive with an incidence of 1/50 000. The prominent clinical characteristic of the disease is the development of bullae or vesicles in mucosa or skin in response to minor trauma. It is a chronic mechanobullous disease characterised by auto antibodies against Type VII collagen. This paper documents a case of a man diagnosed with dominant dystrophic EB; describing the measures that dentists and healthcare providers should adopt in order to provide a safe and effective dental treatment. Early prevention protocols for these patients have also been discussed.


Subject(s)
Epidermolysis Bullosa Dystrophica/diagnosis , Mouth Diseases/diagnosis , Mouth Mucosa/pathology , Rare Diseases/genetics , Diagnosis, Differential , Epidermolysis Bullosa Dystrophica/genetics , Humans , Male , Mouth Diseases/genetics , Phenotype , Young Adult
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