ABSTRACT
Thrombotic complications have been well described in patients with coronavirus disease 2019 (COVID-19) because of its associated states of hypercoagulability and inflammation. We present a unique case of thrombosis of the femoral artery in a 42-year-old man with asymptomatic COVID-19. This case highlights the need for vigilance when treating patients with COVID-19 to make the necessary diagnostic evaluations and provide appropriate treatment.
ABSTRACT
The recent coronavirus disease-2019 (COVID-19) pandemic has caused significant mortality and morbidity, affecting patients of all ages. COVID-19 affects various tissues and systems in the body, including the central and peripheral nervous systems. However, COVID-19 has rarely affected the eyes and caused optic neuritis. We report a unique case of COVID-19-related unilateral optic neuritis in a 10-year-old girl.
ABSTRACT
Foreign body (FB) aspiration is commonly seen in children but less commonly in adolescents. Headscarf pin aspiration is common in Muslim girls, who inappropriately place the pins between their lips while securing the scarf on the head. Bronchoscopy is the treatment modality of choice, and surgery is rarely required. An 11-year-old girl was admitted as a case of accidental aspiration of headscarf pin. X-ray chest showed a radiopaque object in the left bronchus piercing the lung parenchyma. Computed tomography (CT) chest confirmed the diagnosis. The headscarf pin was removed by flexible bronchoscopy as the ear, nose, and throat (ENT) surgeon failed to remove it by rigid bronchoscopy. The FB was removed successfully and the patient was discharged home. Removal of a sharp pin by bronchoscopy is difficult, especially if it pierces the lung parenchyma. In our case, the pin was bent by forceps and then removed by a flexible bronchoscope, which requires a highly skilled professional.
ABSTRACT
Leukocytosis is well recognised in neonate; mostly it is physiological but the counts rarely exceed 30,000/mm(3). Hyperleukocytosis defined as WBC count of more than 100,000 mm(3) is rare and imposes a diagnostic challenge and should be investigated for leukaemia, leukocyte adhesion defect and myeloproliferative disorders. We report a classic case to highlight this entity.
ABSTRACT
Apparent mineralocorticoid excess (AME) syndrome is a rare autosomal recessive disorder due to the deficiency of 11b hydroxysteroid dehydrogenase type 2 enzyme (11beta-HSD2). Mutations in this gene affect the enzymatic activity resulting to an excess of cortisol, which causes its inappropriate access to mineralocorticoid receptor leading to inherited hypertension.This is a potentially fatal but treatable disorder. We present clinical and molecular studies on two sisters diagnosed as AME.
Subject(s)
Mineralocorticoid Excess Syndrome, Apparent/diagnosis , 11-beta-Hydroxysteroid Dehydrogenase Type 2/genetics , Consanguinity , Female , Humans , Infant , Mineralocorticoid Excess Syndrome, Apparent/enzymology , Mineralocorticoid Excess Syndrome, Apparent/genetics , MutationABSTRACT
Epstein Barr virus (EBV) encephalitis is rare in children but can have severe neurological complications and sometimes fatal. It can manifest with varied neurological presentations like meningoencephalitis, brain stem encephalitis, GBS etc. This can appear alone or with clinical picture of infectious mononucleosis. Establishing a diagnosis of EBV encephalitis is difficult and consequently molecular, serological and imaging techniques should be used when investigating a child with encephalitis. To highlight this entity we report two fatal cases of EBV meningoencephalitis presenting with sole neurological manifestations.
Subject(s)
Encephalitis, Viral/diagnosis , Epstein-Barr Virus Infections/diagnosis , Child , Fatal Outcome , Female , Humans , MaleABSTRACT
Organophosphorus poisoning in neonates is extremely rare and needs high index of suspicion to diagnose it. The clinical presentation is often confused with the features of sepsis like apnea, copious oral secretions, diarrhea, letharginess, seizures. There may be recurrence of manifestations due to chronic exposure. We report a classic case admitted in the intensive care unit of our hospital.
