1.
Ann Allergy
; 47(5 Pt 1): 316-9, 1981 Nov.
Article
in English
| MEDLINE
| ID: mdl-7316247
ABSTRACT
Allergic rhinitis patients were challenged with intranasal allergen aerosols after pretreatment with hydroxyzine and phenylpropanolamine, singly and in combination. Hydroxyzine protected against itching, sneezing and hypersecretion but aggravated obstruction. Phenylpropanolamine had a subtle but measurable anti-congestive effect. This model quantitates and confirms the complementary effects of combined antihistamine-decongestant therapy.