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Radiats Biol Radioecol ; 56(5): 469-474, 2016 Sep.
Article in English, Russian | MEDLINE | ID: mdl-30703305

ABSTRACT

The ROS concentration and proliferation activity (Ki67 expression.marker) have been studied in the periphery blood lymphocytes of Moscow and Obninsk citizens, donors, Chernobyl disaster liquidators, inhabitants of the region contaminated after Chernobyl disaster (Klincy) and individuals with prostate cancer. It was shown that ROS concentration in lymphocytes of the liquidators and residents of the polluted region was lowered. But in lymphocytes of patients with tumors the ROS content was higher in comparison with the control. The cell content with Ki67 expression in lymphocytes of the individuals resided in the polluted region and tumor patients was lowered.


Subject(s)
Chernobyl Nuclear Accident , Lymphocytes/pathology , Prostatic Neoplasms/blood , Reactive Oxygen Species/blood , Adult , Aged , Aged, 80 and over , Humans , Ki-67 Antigen/blood , Lymphocytes/radiation effects , Male , Middle Aged , Prostatic Neoplasms/epidemiology , Prostatic Neoplasms/pathology , Reactive Oxygen Species/radiation effects
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