ABSTRACT
No disponible
Subject(s)
Humans , Arthritis, Rheumatoid/drug therapy , Biological Therapy , Synovitis/drug therapy , Methotrexate/administration & dosage , Remission Induction/methodsABSTRACT
No disponible
Subject(s)
Humans , Waiting Lists , Rheumatic Diseases/therapy , Waiting Lists , Medical Care , Rheumatology/trends , Hospital Administration , Referral and ConsultationABSTRACT
La xerostomía es la sensación subjetiva de sequedad bucal debido a la disminución de saliva. Puede afectar hasta a un 30 por ciento de la población general.Aunque en sí misma no es una enfermedad, altera la calidad de vida, especialmente en la población anciana.Suele recibir escasa atención, incluso por los propios médicos y, en ocasiones, el mismo paciente no lo refiere hasta que se pregunta directamente por su existencia. Sin embargo, puede ser el síntoma que oriente de la presencia de enfermedad sistémica, como el síndrome de Sjögren. Las causas más frecuentes son el uso de fármacos xerogénicos, la radioterapia cervical y el síndrome de Sjögren. El diagnóstico inicial de la xerostomía se basa en demostrarla mediante sialometría (flujo salival basal) y el diagnóstico diferencial en la combinación de pruebas dinámicas o funcionales que analizan la reserva salival glandular (flujo salival estimulado, gammagrafía salival) y estructurales (biopsia labial). El primer paso del tratamiento se basa en mantener una hidratación adecuada y evitar el uso de fármacos xerogénicos. El uso de saliva artificial y de fármacos sialogogos como la pilocarpina son la base del tratamiento actual de la xerostomía. (AU)
Subject(s)
Humans , Xerostomia/diagnosis , Xerostomia/etiology , Xerostomia/physiopathology , Xerostomia/therapy , Saliva/physiology , Salivary Glands/physiologySubject(s)
Internal Medicine/trends , Medicine/trends , Specialization , Humans , Internship and Residency/trends , SpainABSTRACT
A quantification method for measuring whole saliva is described. This whole saliva test (WST) consists of a Whatman paper strip, is easily carried out, innocuous, low-cost and single use. Due to its characteristics, it could be considered as the oral equivalent of Schirmer's tear test. A sample of 159 healthy subjects (81 males and 78 females; mean age 31.62 years) participated in this comparative study of this new procedure and two other tests, the draining and the swab test. Correlation was statistically positive among the three types of tests.
Subject(s)
Saliva/metabolism , Salivation/physiology , Specimen Handling/methods , Adolescent , Adult , Aged , Child , Child, Preschool , Evaluation Studies as Topic , Female , Humans , Linear Models , Male , Middle Aged , Secretory Rate , Specimen Handling/instrumentationABSTRACT
The mean leucocyte count (LC) of the synovial fluid (SF) obtained from 22 elbow joints of patients with chronic inflammatory polyarthritides was 23.4 +/- 17.8 x 10(9)/l while the mean LC of the SF from their paired larger knee joints with similar degree of clinically detectable inflammation was 10.9 +/- 9.9 x 10(9)/l (p less than 0.001). The mean of the ratios between the LC of the paired joints (LC elbow/LC knee) was 2.92 +/- 2.07, above the ratio 1.0 (p less than 0.001) which would be expected if the LCs of both joints were similar. Different sizes of the paired joints presumably explained the phenomenon, which may be due to dilution factors. The size of the joint should be considered when interpreting the leucocyte counts of synovial fluid.
Subject(s)
Elbow Joint/pathology , Knee Joint/pathology , Leukocyte Count , Rheumatic Diseases/pathology , Synovial Fluid/cytology , HumansSubject(s)
Gout/diagnosis , Gout/blood , Gout/urine , Humans , Synovial Fluid/analysis , Uric Acid/analysis , Uric Acid/blood , Uric Acid/urineSubject(s)
Arthritis, Infectious/diagnosis , Bacterial Infections , Chondrocalcinosis/complications , Synovial Fluid/analysis , Aged , Aged, 80 and over , Arthritis, Infectious/complications , Brucellosis , Chondrocalcinosis/diagnosis , Diagnosis, Differential , Diagnostic Errors , Escherichia coli Infections , Female , Humans , Male , Middle Aged , Staphylococcal InfectionsABSTRACT
The case of an 8-year-old boy with tuberculous arthritis of the right knee in whom patellar disease was the only radiological abnormality is presented. The patellar findings were a large lytic area with sclerotic borders containing a dense image corresponding to a sequestrum. Open biopsy was necessary for diagnosis, since the radiological abnormalities are consistent with other chronic infectious diseases.