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Metronidazole in the treatment of gas gangrene following lower limb amputation.

Pashby, N L.

J Antimicrob Chemother ; 8(1): 82-3, 1981 Jul.

Article in English | MEDLINE | ID: mdl-7251543

Subject(s)

Amputation, Surgical/adverse effects , Gas Gangrene/drug therapy , Metronidazole/therapeutic use , Aged , Humans , Male

Oral metronidazole in Clostridium difficile colitis.

Pashby, N L; Bolton, R P; Sherriff, R J.

Br Med J ; 1(6178): 1605-6, 1979 Jun 16.

Article in English | MEDLINE | ID: mdl-466143

Subject(s)

Clostridium Infections/drug therapy , Colitis/drug therapy , Metronidazole/therapeutic use , Administration, Oral , Adult , Clindamycin/adverse effects , Colitis/etiology , Female , Humans , Metronidazole/administration & dosage , Middle Aged

Metronidazole prophylaxis and primary wound closure in appendicectomy.

Pashby, N; Mee, W M.

J Antimicrob Chemother ; 4 Suppl C: 25-8, 1978 Sep.

Article in English | MEDLINE | ID: mdl-690056

Subject(s)

Appendectomy/adverse effects , Metronidazole/therapeutic use , Surgical Wound Infection/prevention & control , Anaerobiosis , Appendectomy/methods , Humans , Metronidazole/administration & dosage , Rectum , Suppositories

Metronidazole in prevention and treatment of bacteroides infections in elective colonic surgery.

Willis, A T; Ferguson, I R; Jones, P H; Phillips, K D; Tearle, P V; Fiddian, R V; Graham, D F; Harland, D H; Hughes, D F; Knight, D; Mee, W M; Pashby, N; Rothwell-Jackson, R L; Sachdeva, A K; Sutch, I; Kilbey, C; Edwards, D.

Br Med J ; 1(6061): 607-10, 1977 Mar 05.

Article in English | MEDLINE | ID: mdl-321076

ABSTRACT

A double-blind randomised trial was carried out among 46 patients undergoing elective colonic surgery; 27 patients received prophylactic metronidazole and 19 received placebo. Anaerobic infections did not develop in any of the metronidazole-treated patients, but did develop in 11 (58%) of 19 controls who were subsequently successfully treated with metronidazole.

Subject(s)

Bacteroides Infections/prevention & control , Colon/surgery , Metronidazole/therapeutic use , Postoperative Complications/prevention & control , Bacterial Infections/epidemiology , Clinical Trials as Topic , Gram-Negative Anaerobic Bacteria , Humans , Male , Middle Aged

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