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1.
Health Serv J ; 107(5575): 24-6, 1997 Oct 16.
Article in English | MEDLINE | ID: mdl-10174457

ABSTRACT

The government is likely to move from a centralised corporatist form of governance to a more collaborative approach. This will require chief executives to rely on a style of leadership which derives more from personal influence than positional forms of power. It may be time to discuss the future of politically appointed chairs and whether the chief executive should be the sole local leader. The government's commitment to delegating power to regional tiers is likely to have a major impact on the nature of leadership in the NHS.


Subject(s)
Leadership , Politics , State Medicine/organization & administration , Administrative Personnel , Cooperative Behavior , Economic Competition , Health Care Reform/legislation & jurisprudence , Policy Making , State Medicine/economics , State Medicine/legislation & jurisprudence , United Kingdom
3.
Manag Care Q ; 3(1): 11-28, 1995.
Article in English | MEDLINE | ID: mdl-10140984

ABSTRACT

An organization that identifies and behaves in alignment with a set of core values that are widely shaped by its employees and derived from its history can build a deep sense of community. Consequences of deep community are greater levels of trust and organizational commitment that can, in turn, be harnessed to help the organization more successfully adapt to and cope with future challenges. However, to be successful, an organization needs to go beyond mere espousal of core values and make a sustained and systematic effort to take practical steps to strengthen both the core values and the behaviors that generally flow from them.


Subject(s)
Hospitals, Religious/standards , Organizational Culture , Social Values , Christianity , Communication , Empathy , Hospital-Patient Relations , Hospitals, Religious/organization & administration , Inservice Training , Interpersonal Relations , Minnesota , Organizational Objectives , Personnel Loyalty
4.
Biochem Pharmacol ; 34(8): 1287-91, 1985 Apr 15.
Article in English | MEDLINE | ID: mdl-3888225

ABSTRACT

We examined the effects of captopril on prolidase activity of crude homogenates of various tissues in the rat and in the human. It was found that captopril caused significant inhibition of prolidases from liver, kidney, and intestine in both species, whereas it showed minimal inhibitory effect on erythrocyte prolidase. In the rat, Ki for the inhibition of kidney and liver prolidases was in the range of 25-35 microM while, in the human, the value was considerably higher. The nature of inhibition was found to be competitive both in the rat and in the human. Oral administration of captopril (daily dose, 40 mg/kg) for 7 days in the rat resulted in increased urinary excretion of peptide-bound 4-hydroxy-L-proline compared to controls, indicating in vivo inhibition of tissue prolidases by captopril.


Subject(s)
Captopril/pharmacology , Dipeptidases/antagonists & inhibitors , Proline/analogs & derivatives , Animals , Carbon Radioisotopes , Dipeptidases/blood , Dipeptides , Erythrocytes/enzymology , Female , Humans , Hydroxylysine/urine , Hydroxyproline/urine , In Vitro Techniques , Intestine, Small/enzymology , Kidney/enzymology , Kinetics , Liver/enzymology , Rats , Rats, Inbred Strains , Spectrophotometry
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