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Ann Clin Transl Neurol ; 9(9): 1459-1464, 2022 09.
Article in English | MEDLINE | ID: mdl-36000540

ABSTRACT

Neuronavigated transcranial magnetic stimulation (nTMS) has emerged as a presurgical language mapping tool distinct from the widely used functional magnetic resonance imaging (fMRI). We report fMRI and nTMS language-mapping results in 19 pediatric-epilepsy patients and compare those to definitive testing by electrical cortical stimulation, Wada test, and/or neuropsychological testing. Most discordant results occurred when fMRI found right-hemispheric language. In those cases, when nTMS showed left-hemispheric or bilateral language representation, left-hemispheric language was confirmed by definitive testing. Therefore, we propose nTMS should be considered for pediatric presurgical language-mapping when fMRI shows right-hemispheric language, with nTMS results superseding fMRI results in those scenarios.


Subject(s)
Epilepsy , Language , Adolescent , Brain Mapping/methods , Child , Humans , Magnetic Resonance Imaging/methods , Transcranial Magnetic Stimulation/methods
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