ABSTRACT
BACKGROUND: The outbreak of the COVID-19 pandemic seems to have mental health implications for both people with neurocognitive disorder and their caregivers. OBJECTIVE: The study aimed to shed light on relations between caregiver mental reaction to the pandemic and caregiver distress related to neuropsychiatric symptoms, memory impairment progression, and functional impairment of people with neurocognitive disorder during the period of confinement in Greece. METHODS: The study included caregivers of patients with mild (Nâ=â13) and major (Nâ=â54) neurocognitive disorder. The caregiver-based telephone interview was based on items of the neuropsychiatric inventory questionnaire, the AD8 Dementia Screening Instrument, and the Bristol Activities of Daily Living Scale. Regarding the mental impact of the COVID-19 crisis on caregivers, four single questions referring to their worries in the last seven days were posed, in addition to the scales Generalized Anxiety Disorder 7-Item (GAD-7) and the 22-item Impact of Event Scale-revised (IES-R). A stepwise linear regression model was employed for studying the relationship between caregiver distress and demographic and clinical data and caregiver mental reaction to COVID-19 pandemic outbreak. RESULTS: Caregiver distress severity during the confinement period was influenced not only by memory deficits (pâ=â0.009) and neuropsychiatric symptoms (pâ<â0.001) of patients, but also by caregiver hyperarousal (pâ=â0.003) and avoidance symptoms (pâ=â0.033) and worries directly linked to the COVID-19 crisis (pâ=â0.022). CONCLUSION: These observations provide further evidence for the urgent need for support of caregivers of patients with neurocognitive disorder during the COVID-19 pandemic.
Subject(s)
COVID-19/psychology , Caregivers/psychology , Neurocognitive Disorders/psychology , Neurocognitive Disorders/therapy , Quarantine/psychology , Aged , Aged, 80 and over , COVID-19/epidemiology , Female , Greece/epidemiology , Humans , Male , Middle Aged , Neurocognitive Disorders/epidemiology , Quarantine/trendsSubject(s)
Cholinesterase Inhibitors/therapeutic use , Cognition Disorders/drug therapy , Phenylcarbamates/therapeutic use , Aged , Cholinesterase Inhibitors/administration & dosage , Cognition Disorders/diagnosis , Diagnostic and Statistical Manual of Mental Disorders , Dose-Response Relationship, Drug , Female , Humans , Phenylcarbamates/administration & dosage , Rivastigmine , Severity of Illness IndexABSTRACT
CONTEXT: No rating scales of the neuropsychiatric symptoms of patients with dementia and Alzheimer's disease (AD) have previously been developed or translated. OBJECTIVES: To develop a Hellenic translation of the Neuropsychiatric Inventory (NPI), to evaluate it's reliability and validity, and to compare NPI results in Greek patients referred to a neuropsychiatry clinic for either of two reasons: disturbing behaviors evoking embarrassment and disturbing behaviors evoking fear in the caregiver. METHODS: The Hellenic translations of the NPI, Brief Psychiatric Rating Scale (BPRS), and Emotional Distress Scale (EDS) were compared in evaluating 29 consecutive referrals of patients with AD. RESULTS: The Hellenic NPI (H-NPI) demonstrated a high degree of internal consistency reliability, and of concurrent validity when compared to the BPRS or the EDS. Patients referred for behaviors evoking embarrassment presented with higher scores on NPI ratings of apathy. However, patients referred for behaviors evoking fear presented with higher scores on NPI ratings of aggression and irritability. CONCLUSIONS: These results indicate that the H-NPI is a reliable instrument, able to detect differences in clinically referred groups of AD patients.
