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Clin Biochem ; 38(11): 1041-4, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16143322

ABSTRACT

OBJECTIVES: The purpose of this study was to verify the usefulness of NT-proBNP in the differential diagnosis of dyspnea in a population of patients presenting in the ER with breathlessness. DESIGN AND METHODS: In samples from 122 patients presenting in the ER with acute-severe dyspnea and from 25 subjects enrolled as a "comparison group" (NORM), NT-proBNP levels were measured. Patients have been classified on the basis of discharge diagnosis: pulmonary disease (PD, n = 23), pulmonary concomitant to cardiac disease (MIXED, n = 17), pulmonary embolism (EMB, n = 8), cardiac disease (CARD, n = 56), acute myocardial infarction (AMI, n = 11) and other disease (OTHER, n = 7). RESULTS: A significant difference in NT-proBNP values (P

Subject(s)
Dyspnea/diagnosis , Natriuretic Peptide, Brain/blood , Peptide Fragments/blood , Adult , Aged , Aged, 80 and over , Diagnosis, Differential , Dyspnea/etiology , Female , Heart Diseases/complications , Heart Diseases/diagnosis , Heart Failure/diagnosis , Humans , Lung Diseases/complications , Lung Diseases/diagnosis , Male , Middle Aged , Myocardial Infarction/diagnosis , Pulmonary Embolism/diagnosis
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