Computer-Supported Experiential Learning-Based Tool for Healthcare Skills.

Care experiences and health outcomes may suffer greatly because of healthcare professionals' deficient educational preparation and practices. The limited awareness about the impact of stereotypes, implicit/explicit biases, and Social Determinants of Health (SDH) may result in unpleasant care experiences and healthcare professional-patient relationships. Additionally, as healthcare professionals are no less prone to have biases than other people, it is essential to deliver the learning platform to enhance healthcare skills (e.g., awareness of the importance of cultural humility, inclusive communication proficiencies, awareness of the enduring impact of both SDH and implicit/explicit biases on health outcomes, and compassionate and empathetic attitude) of healthcare professionals which eventually help to raise health equity in society. Moreover, employing the "learning-by-doing" approach directly in real-life clinical practices is less preferable wherein high-risk care is essential. Thus, there is a huge scope to deliver virtual reality-based care practices by engaging the digital experiential learning and Human-Computer Interaction (HCI) approach to enhance patient care experiences, healthcare experiences, and healthcare skills. Thus, this research provides the Computer-Supported Experiential Learning (CSEL) approach-based tool or mobile application that facilitates virtual reality-based serious role-playing scenarios to enhance the healthcare skills of healthcare professionals and for public awareness.

An Interactive Game with Virtual Reality Immersion to Improve Cultural Sensitivity in Health Care.

Purpose: Biased perceptions of individuals who are not part of one's in-groups tend to be negative and habitual. Because health care professionals are no less susceptible to biases than are others, the adverse impact of biases on marginalized populations in health care warrants continued attention and amelioration. Method: Two characters, a Syrian refugee with limited English proficiency and a black pregnant woman with a history of opioid use disorder, were developed for an online training simulation that includes an interactive life course experience focused on social determinants of health, and a clinical encounter in a community health center utilizing virtual reality immersion. Pre- and post-survey data were obtained from 158 health professionals who completed the simulation. Results: Post-simulation data indicated increased feelings of compassion toward the patient and decreased expectations about how difficult future encounters with the patient would be. With respect to attribution, after the simulation participants were less inclined to view the patient as primarily responsible for their situation, suggesting less impact of the fundamental attribution error. Conclusion: This training simulation aimed to utilize components of evidence-based prejudice habit breaking interventions, such as learning more about an individual's life experience to help minimize filling in gaps with stereotyped assumptions. Although training simulations cannot fully replicate or replace the advantages that come with real-world experience, they can heighten awareness in the increase of increasing the cultural sensitivity of clinicians in health care professions for improving health equity.

Efficacy study of non-lanthanide small luminescent molecules as gunshot residue indicators.

The efficiency of using small, non-lanthanide and readily available molecules was tested as luminescent markers for gunshot residue (GSR) analysis. Three luminophores, namely pyrene (Py), fluorescein (Fl) and a Pt-CNN complex (Pt-C) were used in the present study by using their 5 wt% additives to gunpowder filled in a cartridge followed by firing with a 9 mm pistol. The easy visualization of GSR location, collection of GSR samples followed by their identification through various characterization techniques and the possibility of strategically using these markers as a cost-effective alternative compared to any lanthanide material were evaluated through this work. The comparison of physical mixture of marker and gunpowder and surface soaked gunpowder with the same marker (Py) was also evaluated. Spectroscopic (Optical, Luminescence and Raman), Microscopic, Spectrometric (Mass) and thermal analysis (Differential Scanning Calorimetry, DSC) of the marker, gunpowder and GSR residues implies that both the dyes and gunpowder retains their individual properties and those are merely a physical mixture. Overall, the present study clearly demonstrates that these small organic/metal complex based luminophores are cost effective luminescent marker as compared to lanthanide materials for GSR detection / collection and can be strategically use to track the illegal / unauthorized use of gunpowder.

Evaluation of Skin Penetration of Diclofenac from a Novel Topical Non Aqueous Solution: A Comparative Bioavailability Study.

INTRODUCTION: Different topical formulations of diclofenac have varying skin penetration profile. Recent advances in science and technology has led to the development of many new formulations of drugs for topical drug delivery. One such technological development has led to the innovation of Dynapar QPS, a novel, non-aqueous, quick penetrating solution (QPS) of diclofenac diethylamine. AIM: This study was aimed to measure the total exposure from the drug penetrating the skin in healthy human subjects and comparing the relative systemic bioavailability of Dynapar QPS(®) with diclofenac emulgel. MATERIALS AND METHODS: A 200 mg of diclofenac from either Dynapar QPS(®) (5 ml) or emulgel (20 g) was applied on back of subject as per the randomisation schedule. Blood samples were collected up to 16 hours post drug application. Plasma concentration of diclofenac was measured by pre-validated HPLC method. Pharmacokinetic (PK) parameters like Cmax, Tmax, t1/2, AUC0-t, AUC0-∞, and Kel, of diclofenac were determined for both the formulations. RESULTS: Mean Cmax after administration of Dynapar QPS(®) and diclofenac emulgel were 175.93 and 40.04 ng/ml, respectively. Tmax of diclofenac was almost half with QPS compared to emulgel (5.24 hrs versus 9.53 hrs respectively). The mean AUC0-t and AUC0-∞ after administration of Dynapar QPS(®) was higher as compared to diclofenac emulgel (AUC0-t: 1224.19 versus 289.78 ng.h/ml, respectively; AUC0-∞: 1718.21 versus 513.83 ng.h/ml, respectively). None of the subject experienced any adverse event during the study. CONCLUSION: The results indicate an enhanced penetration and subsequent absorption of diclofenac from Dynapar QPS(®) as compared to diclofenac emulgel. Higher penetration is likely to translate into better pain relief in patients.

Heel neuroma: a case study.

UNLABELLED: This article reviews the diagnosis, pathology, and treatment of plantar heel neuroma, an entity that has previously been described and recognized, yet one that we feel warrants further review because of the prevalence of plantar heel pain that does not respond to the usual array of treatments. We feel that neuroma of the medial calcaneal nerve often goes undiagnosed, and may progress to a severely painful condition that requires surgical intervention. In this article, we describe another case of heel neuroma in an otherwise healthy patient with a history of chronic plantar heel pain that was unresponsive to a wide array of nonsurgical treatments. LEVEL OF CLINICAL EVIDENCE: 4.