ABSTRACT
OBJECTIVE: To compare the efficacy of a regional masseteric nerve block (MNB) in the management of myofascial pain of masseteric origin, relative to trigger point injection (TrP-Inj) and intra-oral stabilization appliance (IOA). STUDY DESIGN: A retrospective chart review of 200 patients treated for myofascial pain of masseteric origin was performed. Sixty patients met the eligibility criteria and were grouped based on their treatment regimen; IOA, TrP-Inj or MNB. Pain scores recorded at pre-treatment (baseline), 30 minutes post-treatment, and 2 weeks post-treatment were analyzed. RESULTS: Treatment with MNB resulted in significant reduction in pain at 30 minutes and two weeks post-treatment compared to TrP-Inj and IOA. CONCLUSION: MNB provided an immediate and sustained therapeutic effect for the management of myofascial pain for at least up to two weeks. MNB is a simple and valuable tool in the management of myogenous pain, especially for the non-orofacial pain practitioner.
Subject(s)
Masseter Muscle/innervation , Nerve Block/methods , Temporomandibular Joint Dysfunction Syndrome/therapy , Adolescent , Adult , Aged , Aged, 80 and over , Anesthetics, Local/administration & dosage , Female , Follow-Up Studies , Humans , Injections , Male , Masseter Muscle/drug effects , Middle Aged , Occlusal Splints , Pain Measurement/methods , Retrospective Studies , Time Factors , Treatment Outcome , Trigger Points , Young AdultABSTRACT
OBJECTIVE: The aim of this study was to evaluate the effect of topical treatment with pregabalin and diclofenac on neuropathic orofacial pain induced by infraorbital nerve injury in the rat. STUDY DESIGN: Sixty-four Sprague-Dawley rats underwent infraorbital nerve injury. Seven days after surgery, pain was verified and the rats randomly assigned to topical or systemic treatment with pregabalin or diclofenac, or to no treatment. Pain intensity and motor coordination were assessed at baseline, after surgery, and daily after treatment for 4 consecutive days. Medication plasma levels were assessed at the end of the study. RESULTS: Topical treatment with 10% pregabalin or 5% diclofenac reduced the pain significantly. A significant decrease in motor coordination was found in the systemic pregabalin. The medications' plasma levels were significantly higher in the systemic treatment compared with the topical. CONCLUSIONS: Topical treatment with pregabalin or diclofenac can reduce neuropathic orofacial pain induced by nerve injury.
