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1.
J Nat Sci Biol Med ; 8(2): 139-143, 2017.
Article in English | MEDLINE | ID: mdl-28781476

ABSTRACT

Understanding the microanatomical changes in brain structures is necessary for developing innovative therapeutic approaches to prevent/delay the cognitive impairment in epilepsy. We review here the microanatomical changes in the brain structures related to cognition in epilepsy. Here, we have presented the changes in major brain structures related to cognition, which helps the clinicians understand epilepsy more clearly and also helps researchers develop new treatment procedures.

2.
J Clin Diagn Res ; 7(12): 2939-40, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24551680

ABSTRACT

During routine dissection classes for under graduate students, we found a unique and unusual case regarding the anomalous branching in the third part of the axillary artery was terminated into subscapular arterial trunk, superficial brachial artery and deep brachial artery. The subscapular arterial trunk was origin of several important arteries as the circumflex scapular, thoracodorsal, posterior circumflex humeral, thoraco-acromial and lateral thoracic arteries. The deep brachial artery in the arm gave anterior circumflex humeral artery at the surgical neck of humerus, which terminated in the cubital fossa by dividing into radial and ulnar arteries. The superficial brachial artery gave two profunda brachii arteries, both of which passed through spiral groove, along with radial nerve and three muscular branches, to brachialis muscle. This variation is very rare. As per our knowledge, we did not find any literature which explained variations which were similar to this. The normal and abnormal anatomy of the axillary region has practical importance among vascular radiologists and surgeons and it should be known for making an accurate diagnostic interpretation.

3.
J Inorg Biochem ; 36(2): 107-13, 1989 Jun.
Article in English | MEDLINE | ID: mdl-2547893

ABSTRACT

Five new copper(II) complexes of 5-phenylazo-3-methoxy salicylidene thiosemicarbazone and N4 substituted thiosemicarbazones have been synthesized. They have been characterized by chemical analyses, magnetic, conductance data, and by ultraviolet (UV)--visible, infrared, and electron spin resonance spectra. The complexes have the general formula CuL2, where HL is the ligand. One representative complex has been screened in vitro and in vivo against P388 lymphocytic leukemia cells sensitive and resistant to adriamycin (P388/S and P388/R). It has shown promising growth inhibition activity. We are reporting here for the first time the antineoplastic activity of this complex against experimental tumor systems.


Subject(s)
Antineoplastic Agents/chemical synthesis , Organometallic Compounds/chemical synthesis , Thiosemicarbazones/chemical synthesis , Tumor Cells, Cultured/drug effects , Animals , Antineoplastic Agents/analysis , Copper/analysis , Copper/pharmacology , Doxorubicin/pharmacology , Drug Resistance , Drug Screening Assays, Antitumor , Electron Spin Resonance Spectroscopy , Leukemia P388/pathology , Ligands , Mice , Mice, Inbred Strains , Organometallic Compounds/analysis , Organometallic Compounds/pharmacology , Spectrophotometry , Spectrophotometry, Ultraviolet , Thiosemicarbazones/analysis , Thiosemicarbazones/pharmacology
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