ABSTRACT
Snake bite is one of the major public health problems in India. Venom induced consumption coagulopathy(VICC) is the commonest coagulopathy resulting from viper bites. Anti-snake venom(ASV) is the only mainstay therapy in the management of snake bite. Despite anti-venom being efficacious and bonding to multiple toxins in the venom, there are number of reasons it may not be effective. The most important being irreversible toxic effects cannot be reversed by antivenom to toxin after damage has occurred, such as clotting factor deficiencies resulting from VICC. This study was done to evaluate the efficacy of use of anti-snake venom and ASV with fresh frozen plasma (FFP) in haemotoxic snake bites in a tertiary care hospital. Total 500 patients admitted during period from January 2010- April 2017 with history of snake bite. vasculotoxic[278], neurotoxic[126], localtoxic[64] and nontoxic[32]. Overall outcome in term of time recovery, renal complications, and death better in ASV plus FFP group. The complications due to snake bite were minimum, if anti snake venom was administered within first 4 hours.
