ABSTRACT
A 48-year-old man, a known case of Friedreich's ataxia (FRDA) underwent cardiac fluorodeoxyglucose (FDG) positron emission tomography -computed tomography (PET/CT) for evaluation of myocardial viability. Tetrofosmin images showed an enlarged left ventricular cavity with small mid and basal inferior and apical infarct global hypokinesia with ejection fraction of 39%. Fluorodeoxyglucose images showed poor quality myocardial images. Friedreich's ataxia is associated with a high incidence of diabetes mellitus. Non-diabetic patients with Friedreich's ataxia have insulin resistance. This is associated with a reduction in the affinity of insulin receptors and membrane abnormality that alters the binding function of the insulin receptor.
ABSTRACT
A 66-year-old male patient presented with low grade fever without chills associated with simple partial seizures. He was advised whole body positron emission tomography-computed tomography (PET/CT) (fluorodeoxyglucose PET/CT) scan which demonstrated an increase in metabolic activity in the limbic system. There was no evidence of active disease anywhere else in the body. Thus, in the setting of limbic encephalitis PET-CT helps in locating the cancerous origin as well as gives information about functional abnormality of the brain.
