[Preventive and therapeutic efficacy of the vaccine against trychophytosis in cattle]. / Preventivní a lécebná úcinnost vakcíny proti trichofytóze u skotu.

The effectiveness of vaccine against dermatomycosis, caused by Trichophyton verrucosum, was studied in young cattle in three herds. The vaccines of Czechoslovak and Soviet production had almost the same effectiveness in prevention. In healthy calves without clinical signs of trichophytosis vaccinated at an age of one to three months with a dose of 2.5 to 5.0 ml, applied intramuscularly, and revaccinated with due respect to the rules of hygiene in the calf-houses, an incidence of 0 to 13% in the three- to five-month period of study was observed. In the non-vaccinated control groups, the incidence under the same infection conditions and in the same period was 36.3 to 100.0%. At the early stage of vaccination--during the inoculation of the animals suspected of being infected--the incidence of the disease was 50.0 to 68.8% and mostly showed no difference from incidence observed in the nonvaccinated control cattle. The therapeutic effect of the vaccine and Mykolastanox F is characterized by the fact that zero prevalence was obtained in the animals ten weeks after vaccination. Animals treated locally with Mykolastanox F showed zero prevalence 12 weeks after the beginning of treatment.

[Virulence of Mycobacterium avium and Mycobacterium intracellulare in pigs during experimental and spontaneous infection]. / Virulence Mycobacterium avium a Mycobacterium intracellulare pro prasata pri experimentální a spontánní infekci

The virulence of M. avium and M. intracellulare was studied in 16 experimentally infected pigs and on 174 animals coming from herds spontaneously infected with the mentioned Mycobacterium species. The result of the patho-anatomic examination and cultivation from samples of lymph nodes, organs, muscles, and excrements proved a higher virulence of M. avium to experimentally and spontaneously infected pigs, as compared with M. intracellulare. The strains of M. avium and M. intracellulare sensibilized all pigs to aviary tuberculin within 80 days from peroral and intranasal infection. Patho-anatomic changes in pigs spontaneously infected with M. avium were proved in 10% of the animals that showed a negative reaction to aviary tuberculin.