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1.
Transplant Proc ; 42(5): 1979-81, 2010 Jun.
Article in English | MEDLINE | ID: mdl-20620561

ABSTRACT

After single lung transplantation for emphysema native lung hyperinflation is a common complication that may cause respiratory failure. Herein we have reported satisfactory bronchoscopic lung volume reduction in a left single-lung transplant recipient with native lung hyperinflation, who suffered from Medical Research Council (MRC) class 3 dyspnea and chest pain. Three endobronchial valves (Zephyr; Emphasys Medical, Redwood, Calif, United States) were placed into the segmental bronchi of the right upper lobe, using videobronchoscopy under general anesthesia. Postoperative chest computed tomography revealed subsegmental atelectasis in that lobe. The clinical benefit was an improved MRC dyspnea class from 3 to 2, which was still present at 4 months after the procedure, although there were no remarkable changes in spirometric parameters.


Subject(s)
Lung Transplantation/adverse effects , Lung/anatomy & histology , Pulmonary Emphysema/surgery , Bronchoscopy/methods , Female , Forced Expiratory Volume , Humans , Lung Transplantation/diagnostic imaging , Middle Aged , Pulmonary Atelectasis/diagnostic imaging , Pulmonary Emphysema/diagnostic imaging , Pulmonary Valve/surgery , Radiography, Thoracic , Treatment Outcome
2.
Transplant Proc ; 41(6): 2221-2, 2009.
Article in English | MEDLINE | ID: mdl-19715879

ABSTRACT

BACKGROUND: Lung transplantation (LTx) has been established as the last treatment option in certain lung diseases. It is not uncommon for complications to occur that require urgent reoperation. The objective of our study was to analyze the characteristics of lung transplant patients who required reoperation in the postoperative period. PATIENTS AND METHODS: We have conducted a retrospective descriptive study of 224 lung transplants from January 1999 to September 2008, excluding retransplants. A subgroup of 16 subjects (7.2%) required reoperations. RESULTS: These 16 individuals had a mean age of 49.38 +/- 14.32 years with 75% men and 25% women. The disease leading to LTx was emphysema in 6 (37.5%), pulmonary fibrosis in 5 (31.3%), pulmonary hypertension in 2 (12.5%) and bronchiectasis, cystic fibrosis, and lymphangioleiomyomatosis in 1 each (6.3%). Preoperatively, 40% were taking corticosteroids. Double lung transplantation was performed in 56.3% and single lung in 43.7%. LTx surgery was prolonged in 68.8% of patients and intraoperative complications were more frequent than in the other patients (P = .041). The causes for reoperation were bleeding in 13 (of these, 5 had severe adhesions and 4 required extracorporeal circulation during LTx); bronchial dehiscence in 1; wall dehiscence in 1; and vascular stenosis in 1. At the end of the study, 62.5% were alive and among the 6 who died, 3 succumbed as a result of the surgery. Most subjects underwent late reoperation after a mean of 16 days from transplantation (range, 1-55). The need for reoperation was not associated with greater perioperative mortality. CONCLUSIONS: The incidence of reoperation in the postoperative period was low in our series. The main cause was bleeding. In more than half of the cases, LTx surgery was prolonged and intraoperative complications were more frequent. The need for reoperation was not associated with greater perioperative mortality.


Subject(s)
Lung Transplantation/adverse effects , Postoperative Complications/surgery , Reoperation/statistics & numerical data , Adult , Bronchiectasis/surgery , Cystic Fibrosis/surgery , Female , Humans , Lymphangiosarcoma/surgery , Male , Middle Aged , Postoperative Complications/mortality , Pulmonary Emphysema/surgery , Reoperation/mortality , Retrospective Studies
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