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1.
Support Care Cancer ; 30(3): 2693-2703, 2022 Mar.
Article in English | MEDLINE | ID: mdl-34822001

ABSTRACT

PURPOSE: People diagnosed with cancer experience high distress levels throughout diagnosis, treatment, and survivorship. Untreated distress is associated with poor outcomes, including worsened quality of life and higher mortality rates. Distress screening facilitates need-based access to supportive care which can optimize patient outcomes. This qualitative interview study explored outpatients' perceptions of a distress screening process implemented in an Australian cancer center. METHODS: Adult, English-speaking cancer outpatients were approached to participate in face-to-face or phone interviews after being screened by a clinic nurse using the distress thermometer (DT). The piloted semi-structured interview guide explored perceptions of the distress screening and management process, overall well-being, psychosocial support networks, and improvement opportunities for distress processes. Thematic analysis was used. RESULTS: Four key themes were identified in the 19 interviews conducted. Distress screening was found to be generally acceptable to participants and could be conducted by a variety of health professionals at varied time points. However, some participants found "distress" to be an ambiguous term. Despite many participants experiencing clinical distress (i.e., DT ≥ 4), few actioned referrals; some noted a preference to manage and prevent distress through informal support and well-being activities. Participants' diverse coping styles, such as positivity, acceptance, and distancing, also factored into the perceived value of screening and referrals. CONCLUSION AND IMPLICATIONS: Screening models only measuring severity of distress may not be sufficient to direct care referrals, as they do not consider patients' varying coping strategies, external support networks, understanding of distress terminology, and motivations for accessing supportive care services.


Subject(s)
Neoplasms , Quality of Life , Adult , Australia , Early Detection of Cancer , Humans , Mass Screening , Neoplasms/diagnosis , Neoplasms/therapy , Outpatients
2.
Transl Behav Med ; 11(8): 1481-1494, 2021 08 13.
Article in English | MEDLINE | ID: mdl-33677606

ABSTRACT

Guidelines for chronic noncancer pain prioritize behavioral treatments. In clinical practice transition from opioids to behavioral treatments is often not endorsed by patients or providers. Feasible interventions to support opioid tapering are needed, particularly in primary care. The objectives of this paper is to review the feasibility of behavioral interventions to support opioid tapering. Electronic databases (MEDLINE, Embase, PsycINFO, and CINAHL) were searched from inception to June 2019 to identify original studies reporting feasibility (consent rates; completion rates; patient-reported acceptability; integration into clinical practice; and adverse events) of opioid tapering and transition to behavioral treatments for adults experiencing chronic noncancer pain. Google scholar and contents tables of key journals were also searched. Two authors independently extracted data and assessed methodological quality using The Quality Assessment Tool for Quantitative Studies. Eleven publications met inclusion criteria, of which three were conducted in primary care. Consent rates ranged from 27% to 98% and completion rates from 6.6% to 100%. Four studies rated at least one component of patient acceptability: helpfulness from 50%-81%; satisfaction 71%-94%, and "recommend to others" 74%-91%. Three studies reported provider perspectives and two studies reported adverse events. Quality assessment indicated all 11 studies were moderate or weak, primarily due to selection bias and lack of assessor blinding. There was also considerable heterogeneity in study design. The limited available data suggest that attempts to translate opioid tapering interventions into practice are likely to encounter substantial feasibility challenges. One possible way to ameliorate this challenge may be a clear policy context, which facilitates and support opioid reduction.


Subject(s)
Analgesics, Opioid , Chronic Pain , Adult , Behavior Therapy , Chronic Pain/drug therapy , Feasibility Studies , Humans , Primary Health Care
3.
Genes (Basel) ; 11(11)2020 10 29.
Article in English | MEDLINE | ID: mdl-33137935

ABSTRACT

BACKGROUND: We demonstrated that the transduction of Wnt11 into mesenchymal stem cells (MSCs) (MSCWnt11) promotes these cells differentiation into cardiac phenotypes. In the present study, we investigated the paracrine effects of MSCWnt11 on cardiac function and angiogenesis. METHODS AND RESULTS: Conditioned medium was collected from MSCWnt11 (CdMWnt11) and their control cells (CdMGFP). CdMWnt11, especially obtained from MSCWnt11 exposed to hypoxia, significantly promoted human umbilical vein endothelial cells (HUVECs) migration and increased capillary-like tube (CLT) formation, which was blocked by Wnt11 neutralizing antibody. Wnt11 protein was significantly higher in CdMWnt11 compared to that in CdMGFP. Directly treating HUVECs with recombinant Wnt11 protein significantly increased CLT formation, which was abrogated by treating cells with the JNK inhibitor SP600125, as well as the PKC inhibitor Calphostin-C. Moreover, the transfection of Wnt11 to HUVECs (HWnt11) significantly increased CLT formation and HUVEC migration, as well as upregulated p-pan-PKC and p-JNK expression. Injection of CdMWnt11 into the peri-infarct region in a rat acute myocardial infarction (AMI) model significantly improved cardiac function, reduced infarct size, and increased myocardial blood flow and blood vessel density in the ischemic area. CONCLUSION: Wnt11 released from MSCWnt11 increased angiogenesis and improved cardiac function via non-canonical Wnt-PKC-JNK dependent pathways.


Subject(s)
Mesenchymal Stem Cells/cytology , Mesenchymal Stem Cells/metabolism , Neovascularization, Physiologic , Wnt Proteins/metabolism , Wnt Signaling Pathway , Animals , Capillaries/cytology , Capillaries/growth & development , Capillaries/metabolism , Cells, Cultured , Culture Media, Conditioned , Disease Models, Animal , Female , Human Umbilical Vein Endothelial Cells , Humans , MAP Kinase Signaling System , Myocardial Infarction/metabolism , Myocardial Infarction/physiopathology , Neovascularization, Physiologic/genetics , Protein Kinase C/metabolism , Rats , Rats, Sprague-Dawley , Rats, Transgenic , Recombinant Proteins/genetics , Recombinant Proteins/metabolism , Wnt Proteins/antagonists & inhibitors , Wnt Proteins/genetics , Wnt Signaling Pathway/genetics
4.
Support Care Cancer ; 28(1): 249-259, 2020 Jan.
Article in English | MEDLINE | ID: mdl-31030278

ABSTRACT

BACKGROUND: It is unknown how many distressed patients receive the additional supportive care recommended by Australian evidence-based distress management guidelines. The study identifies the (1) distress screening practices of Australian cancer services; (2) barriers to improving practices; and (3) implementation strategies which are acceptable to service representatives interested in improving screening practices. METHOD: Clinic leads from 220 cancer services were asked to nominate an individual involved in daily patient care to complete a cross-sectional survey on behalf of the service. Questions related to service characteristics; screening and management processes; and implementation barriers. Respondents indicated which implementation strategies were suitable for their health service. RESULTS: A total of 122 representatives participated from 83 services (51%). The majority of respondents were specialist nurses or unit managers (60%). Approximately 38% of representatives' services never or rarely screen; 52% who screen do so for all patients; 55% use clinical interviewing only; and 34% follow referral protocols. The most common perceived barriers were resources to action screening results (74%); lack of time (67%); and lack of staff training (66%). Approximately 65% of representatives were interested in improving practices. Of the 8 implementation strategies, workshops (85%) and educational materials (69%) were commonly selected. Over half (59%) indicated a multicomponent implementation program was preferable. CONCLUSIONS: Although critical gaps across all guideline components were reported, there is a broad support for screening and willingness to improve. Potential improvements include additional services to manage problems identified by screening, more staff time for screening, additional staff training, and use of patient-report measures.


Subject(s)
Mass Screening , Neoplasms/psychology , Practice Patterns, Physicians'/standards , Stress, Psychological/diagnosis , Stress, Psychological/therapy , Adult , Australia/epidemiology , Cancer Care Facilities/standards , Clinical Audit , Cross-Sectional Studies , Delivery of Health Care/standards , Female , Guideline Adherence/statistics & numerical data , Humans , Male , Mass Screening/methods , Mass Screening/standards , Neoplasms/diagnosis , Neoplasms/epidemiology , Neoplasms/therapy , Practice Patterns, Physicians'/statistics & numerical data , Psychological Distress , Quality Improvement/standards , Referral and Consultation/standards , Referral and Consultation/statistics & numerical data , Stress, Psychological/epidemiology , Stress, Psychological/etiology , Surveys and Questionnaires
5.
Support Care Cancer ; 28(5): 2059-2069, 2020 May.
Article in English | MEDLINE | ID: mdl-31872298

ABSTRACT

PURPOSE: People affected by chronic diseases such as cancer report high levels of distress and a need for psychosocial support. It is unclear whether telephone-based services for people affected by chronic disease are a practical setting for implementing distress screening, referral protocols and rescreening to direct supportive care where it is needed. This systematic review aimed to describe the published literature regarding distress screening and supportive care referral practices in telephone-based services for people affected by chronic diseases such as cancer. METHODS: A systematic literature search of MEDLINE, Embase, PsycInfo, CINAHL, Cochrane and Scopus was conducted in February 2018. Included quantitative studies involved: patients or caregivers affected by chronic diseases including cancer and describe a health service assessing psychosocial needs or distress via telephone. Extracted data included the type of cancer or other chronic disease, sample size, screening tool, referral or rescreening protocols, and type of health service. RESULTS: The search identified 3989 potential articles with additional searches returning 30 studies (n = 4019); fourteen were eligible for full-text review. Of the 14 studies, 13 included cancer patients. Studies were across multiple settings and identified nine distress screening tools in use. CONCLUSION: The reviewed studies indicate that validated distress-screening tools are being used via telephone to identify distress, particularly in relation to cancer. Screening-driven supportive care referrals are also taking place in telephone-based services. However, not all services use an established referral protocol. Ongoing rescreening of callers' distress is also limited despite it being an important recommendation from psycho-oncology guidelines.


Subject(s)
Neoplasms/psychology , Psychosocial Support Systems , Referral and Consultation/statistics & numerical data , Telephone/statistics & numerical data , Caregivers/psychology , Chronic Disease/psychology , Humans , Male , Mass Screening , Research
6.
Am J Health Promot ; 31(3): 209-216, 2017 05.
Article in English | MEDLINE | ID: mdl-26559713

ABSTRACT

PURPOSE: Evaluate the perceived effectiveness of key antismoking messages among highly disadvantaged smokers and assess the impact of nicotine dependence and cessation cognitions on message processing. DESIGN: The experimental crossover trial, undertaken between March and December 2012, randomly exposed participants to two of three antismoking advertisements delivered via touchscreen computer. SETTING: Welfare recipients were recruited from a community service organization in New South Wales, Australia. SUBJECTS: Subjects were 354 smokers (79% response rate). Participants resided in government rental housing (52%), earned less than AUD$400/wk (72%), and received their primary income from government welfare (95%). INTERVENTION: Three 30-second antismoking television advertisements representing common campaign themes: why to quit (graphic imagery), why to quit (personal testimonial), or how to quit. MEASURES: An 11-item scale assessed perceived effectiveness and message acceptance. An eight-item cessation cognitions index assessed motivations and readiness to quit, and the heaviness of smoking index was used to classify nicotine dependence. ANALYSIS: Descriptive statistics, generalized linear mixed models, and multiple linear regression analyses are reported. RESULTS: Why-to-quit advertisements were perceived as significantly more effective than the how-to-quit advertisement (all p < .0001). Smokers with positive cessation cognitions were more likely to accept antismoking messages (p = .0003) and perceive them as effective (p < .0001). Nicotine dependence level did not influence message acceptance (p = .7322) or effectiveness (p = .8872). CONCLUSION: Highly emotive advertisements providing good reasons to quit may be the most effective in promoting the antismoking message among groups with high smoking rates.


Subject(s)
Advertising/methods , Health Promotion/methods , Poverty , Smoking Cessation/psychology , Adolescent , Adult , Australia , Cross-Over Studies , Female , Humans , Male , Middle Aged , Perception , Young Adult
7.
Ann Hematol ; 95(12): 2065-2076, 2016 Dec.
Article in English | MEDLINE | ID: mdl-27623627

ABSTRACT

Haematological cancer often necessitates that individuals make significant lifestyle and behaviour changes to protect themselves against infections. It is essential that haematological cancer survivors receive the support and information they require to adjust to such changes. This cross-sectional survey of 259 haematological cancer survivors found that over two thirds of haematological cancer survivors would like to receive more detailed information or help with: diet and nutrition that takes into account their diagnosis and treatment, how to manage the symptoms from the cancer and/or treatment, signs and symptoms to be aware of that may indicate a possible infection and appropriate exercise. Over a third of survivors reported that they had to make changes to reduce their chance of infection, with social restriction the most commonly reported area of change survivors made. Improving communication and access to care and providing additional emotional support may assist survivors in making these additional changes. Healthcare providers should use this information to better support haematological cancer survivors in dealing with the effects haematological cancer has on their life.


Subject(s)
Adaptation, Psychological , Hematologic Neoplasms/diagnosis , Hematologic Neoplasms/psychology , Survivors/psychology , Adolescent , Adult , Aged , Australia/epidemiology , Cross-Sectional Studies , Female , Hematologic Neoplasms/epidemiology , Humans , Male , Middle Aged , Young Adult
8.
Trials ; 17(1): 290, 2016 06 14.
Article in English | MEDLINE | ID: mdl-27301489

ABSTRACT

BACKGROUND: The provision of smoking cessation support in Australian drug and alcohol treatment services is sub-optimal. This study examines the cost-effectiveness of an organisational change intervention to reduce smoking amongst clients attending drug and alcohol treatment services. METHODS/DESIGN: A cluster-randomised controlled trial will be conducted with drug and alcohol treatment centres as the unit of randomisation. Biochemically verified (carbon monoxide by breath analysis) client 7-day-point prevalence of smoking cessation at 6 weeks will be the primary outcome measure. The study will be conducted in 33 drug and alcohol treatment services in four mainland states and territories of Australia: New South Wales, Australian Capital Territory, Queensland, and South Australia. Eligible services are those with ongoing client contact and that include pharmacotherapy services, withdrawal management services, residential rehabilitation, counselling services, and case management services. Eligible clients are those aged over 16 years who are attending their first of a number of expected visits, are self-reported current smokers, proficient in the English language, and do not have severe untreated mental illness as identified by the service staff. Control services will continue to provide usual care to the clients. Intervention group services will receive an organisational change intervention, including assistance in developing smoke-free policies, nomination of champions, staff training and educational client and service resources, and free nicotine replacement therapy in order to integrate smoking cessation support as part of usual client care. DISCUSSION: If effective, the organisational change intervention has clear potential for implementation as part of the standard care in drug and alcohol treatment centres. TRIAL REGISTRATION: Australian and New Zealand Clinical Trials Registry, ACTRN12615000204549 . Registered on 3 March 2015.


Subject(s)
Delivery of Health Care, Integrated/organization & administration , Drug Users/psychology , Smokers/psychology , Smoking Cessation/methods , Smoking/therapy , Substance Abuse Treatment Centers/organization & administration , Substance-Related Disorders/rehabilitation , Australia , Clinical Protocols , Cost-Benefit Analysis , Delivery of Health Care, Integrated/economics , Health Care Costs , Humans , Organizational Innovation , Research Design , Smoking/adverse effects , Smoking/economics , Smoking/psychology , Smoking Cessation/economics , Smoking Cessation/psychology , Substance Abuse Treatment Centers/economics , Substance-Related Disorders/diagnosis , Substance-Related Disorders/economics , Substance-Related Disorders/psychology , Time Factors , Treatment Outcome
9.
Support Care Cancer ; 24(10): 4413-22, 2016 10.
Article in English | MEDLINE | ID: mdl-27245984

ABSTRACT

PURPOSE: To explore outcomes of psychological distress, including anxiety, depression and stress, amongst adult haematological cancer survivors, with a specific focus on potential differences between rural and urban survivors. METHODS: One thousand four hundred fourteen urban and rural survivors were recruited from five Australian population-based cancer registries and completed a self-report pen-and-paper survey on their well-being, including the Depression Anxiety and Stress Scale 21-item version. RESULTS: A quarter of survivors were identified as reporting above normal levels of anxiety and depression, respectively, and almost one fifth (17 %) reported above normal levels of stress. There were no statistically significant differences in the percentage of rural and urban survivors reporting above normal levels of anxiety, depression, or stress. Survivors who had experienced financial burden due to their cancer or were of middle age had higher odds of reporting multiple domains of psychological distress, compared to their counterparts. CONCLUSIONS: Haematological cancer survivors diagnosed during middle age or who experience increased financial burden as a result of their diagnosis may require additional support and care with regards to psychological distress.


Subject(s)
Hematologic Neoplasms/psychology , Stress, Psychological/psychology , Adolescent , Adult , Aged , Female , Hematologic Neoplasms/mortality , Humans , Male , Middle Aged , Prevalence , Surveys and Questionnaires , Survivors/psychology , Young Adult
10.
Crit Rev Oncol Hematol ; 97: 247-62, 2016 Jan.
Article in English | MEDLINE | ID: mdl-26412718

ABSTRACT

To conduct a comprehensive review to examine among hematological cancer patients: (1) rates of adherence to self-administered cancer treatments; and (2) factors impacting on their adherence. Fifty two eligible publications were identified. The majority focused on Chronic Myeloid Leukaemia (CML) (n=40) and Acute Lymphoid Leukaemia (ALL) (n=11) patients. Adherence rates varied and depended on the definition and measures used. Patient understanding about their disease and treatment, and forgetting to take their medication impacted on patients' level of adherence; while the use of reminders reduced forgetfulness. There is a lack of valid and reliable information relating to medication adherence of hematological cancer patients. Based on the limited data available we provide a profile of CML and ALL patients at potential risk of medication non-adherence, as well as a proposed checklist that can be used by health care providers in assessing and supporting patients in adhering to their medication.


Subject(s)
Hematologic Neoplasms/drug therapy , Medication Adherence , Antineoplastic Agents/therapeutic use , Humans
11.
BMJ Open ; 5(9): e008419, 2015 Sep 14.
Article in English | MEDLINE | ID: mdl-26369799

ABSTRACT

OBJECTIVES: This study examined sociodemographic, smoking and psychosocial characteristics associated with consent to participate in a smoking cessation trial for socially disadvantaged smokers. DESIGN: Baseline data were collected prior to seeking consent for the Call it Quits, a randomised controlled trial. SETTING: An Australian social and community service organisation. Sociodemographic, smoking and psychosocial characteristics were compared between smokers who agreed or declined to participate. PARTICIPANTS: Of the 584 smokers invited to participate, 431 (74%) consented and 153 (26%) declined. RESULTS: Logistic regression modelling indicates the ORs of participation were twice as high for those reporting 'high' motivation to quit compared to the 'moderate' motivation group, and five times higher than the 'low' motivation group (p=0.007). The ORs of consenting were higher for those with a preference for gradual reduction in cigarettes in quit attempts compared with 'no preference'. The ORs were lower for those reporting 'don't know' regarding their enjoyment of smoking compared to 'not at all' enjoying smoking, and reporting that fewer of their family or friends smoked compared to 'most or all'. CONCLUSIONS: This study is the first to examine the characteristics of socially disadvantaged smokers who consent or decline to participate in a smoking cessation trial. Low-income smokers who are motivated to quit, are not enjoying smoking, had family or friends who smoked, and who are interested in gradual cessation approaches may be more likely to participate in a smoking cessation trial. TRIAL REGISTRATION NUMBER: ISRCTN85202510.


Subject(s)
Health Promotion/organization & administration , Patient Participation/psychology , Refusal to Participate/psychology , Smoking Cessation/psychology , Smoking/psychology , Tobacco Use Disorder/prevention & control , Vulnerable Populations/psychology , Adult , Attitude to Health , Australia/epidemiology , Cross-Sectional Studies , Female , Humans , Male , Motivation , Odds Ratio , Patient Participation/statistics & numerical data , Program Development , Randomized Controlled Trials as Topic , Refusal to Participate/statistics & numerical data , Smoking/epidemiology , Smoking Cessation/methods , Smoking Prevention , Vulnerable Populations/statistics & numerical data
12.
PLoS One ; 9(12): e114778, 2014.
Article in English | MEDLINE | ID: mdl-25490546

ABSTRACT

OBJECTIVE: To assess emergency physicians' perceptions of individual and system enablers to the use of tissue Plasminogen Activator in acute stroke. METHOD: Australian fellows and trainees of Australasian College for Emergency Medicine completed a 57-item online survey assessing enablers to implementation of evidence-based practice across six domains: knowledge, skills, modelling, monitoring, feedback, and maintenance. Demographic and workplace characteristics were obtained. Descriptive statistics were calculated to describe demographic and workplace characteristics of responders, and survey responses. Each domain received an overall score (%) based on the number of responders agreeing with all items within the domain. RESULTS: A total of 429 (13%) Australasian College for Emergency Medicine members responded. 17.7% of respondents reported they and/or their workplace met all knowledge-related enablers, however only 2.3% had all skill-related enablers in place. Of respondents who decide which patients receive tissue Plasminogen Activator treatment, 18.1% agreed that all maintenance-related enablers are in place at their hospital, compared to 6.6% for those who do not decide which patients receive tissue Plasminogen Activator treatment. None of the respondents had all items in place cross all domains. CONCLUSIONS: Even when allowing for the low response rate, it seems likely there is a lack of individual and system enablers supporting the implementation of best-practice stroke care in a number of Australian hospitals. Quality improvement programs could target all domains, particularly the skills-training and feedback emergency physicians receive, to aid implementation of tissue Plasminogen Activator treatment for acute stroke.


Subject(s)
Attitude of Health Personnel , Fibrinolytic Agents/therapeutic use , Health Knowledge, Attitudes, Practice , Quality Improvement , Stroke/drug therapy , Tissue Plasminogen Activator/therapeutic use , Acute Disease , Adult , Cross-Sectional Studies , Emergency Medicine , Female , Health Care Surveys , Hospitals , Humans , Male , Physicians
13.
BMC Med Res Methodol ; 14: 42, 2014 Mar 25.
Article in English | MEDLINE | ID: mdl-24669751

ABSTRACT

BACKGROUND: This study aims to review the literature regarding the barriers to sampling, recruitment, participation, and retention of members of socioeconomically disadvantaged groups in health research and strategies for increasing the amount of health research conducted with socially disadvantaged groups. METHODS: A systematic review with narrative synthesis was conducted. Searches of electronic databases Medline, PsychInfo, EMBASE, Social Science Index via Web of Knowledge and CINHAL were conducted for English language articles published up to May 2013. Qualitative and quantitative studies as well as literature reviews were included. Articles were included if they reported attempts to increase disadvantaged group participation in research, or the barriers to research with disadvantaged groups. Groups of interest were those described as socially, culturally or financially disadvantaged compared to the majority of society. Eligible articles were categorised according to five phases of research: 1) sampling, 2) recruitment and gaining consent, 3) data collection and measurement, 4) intervention delivery and uptake, and 5) retention and attrition. RESULTS: In total, 116 papers from 115 studies met inclusion criteria and 31 previous literature reviews were included. A comprehensive summation of the major barriers to working with various disadvantaged groups is provided, along with proposed strategies for addressing each of the identified types of barriers. Most studies of strategies to address the barriers were of a descriptive nature and only nine studies reported the results of randomised trials. CONCLUSIONS: To tackle the challenges of research with socially disadvantaged groups, and increase their representation in health and medical research, researchers and research institutions need to acknowledge extended timeframes, plan for higher resourcing costs and operate via community partnerships.


Subject(s)
Cultural Deprivation , Health Services Accessibility , Poverty , Vulnerable Populations , Biomedical Research , Health Status Disparities , Healthcare Disparities , Humans
14.
BMJ Open ; 4(2): e004078, 2014 Feb 06.
Article in English | MEDLINE | ID: mdl-24503299

ABSTRACT

OBJECTIVES: This study aimed to test the potential impact of plain packaging for cigarettes on brand appeal among highly socioeconomically disadvantaged smokers using the new design for cigarettes implemented in Australia, which combines plain packaging with larger health warning labels. DESIGN: A 2×2 factorial design trial embedded within a cross-sectional computer touchscreen survey. Data were collected between March and December 2012. SETTING: Socially disadvantaged welfare aid recipients were recruited through a large Social and Community Service Organisation in New South Wales, Australia. PARTICIPANTS: N=354 smokers. The majority of the sample had not completed high school (64%), earned less than $A300/week (55%) and received their income from Government payments (95%). INTERVENTIONS: Participants were randomised to one of the four different pack conditions determined by brand name: Winfield versus Benson & Hedges, and packaging type: branded versus plain. Participants were required to rate their assigned pack on measures of brand appeal and purchase intentions. RESULTS: Plain packaging was associated with significantly reduced smoker ratings of 'positive pack characteristics' (p<0.001), 'positive smoker characteristics' (p=0.003) and 'positive taste characteristics' (p=0.033) in the Winfield brand name condition only. Across the four pack conditions, no main differences were found for 'negative smoker characteristics' (p=0.427) or 'negative harm characteristics' (p=0.411). In comparison to plain packaging, the presentation of branded packaging was associated with higher odds of smokers' purchase intentions (OR=2.18, 95% CI 1.34 to 3.54; p=0.002). CONCLUSIONS: Plain packs stripped of branding elements, featuring larger health warning labels, were associated with reduced positive cigarette brand image and purchase intentions among highly socioeconomically disadvantaged smokers.


Subject(s)
Product Packaging , Smoking/psychology , Social Welfare , Adolescent , Adult , Cross-Sectional Studies , Demography , Female , Humans , Male , New South Wales , Surveys and Questionnaires
15.
Drug Alcohol Rev ; 33(2): 169-76, 2014 Mar.
Article in English | MEDLINE | ID: mdl-24372899

ABSTRACT

INTRODUCTION AND AIMS: Understanding how tobacco, alcohol and mental health are related is important for developing population-level policies and individual-level treatments that target comorbidities. The current study aimed to examine sociodemographic characteristics and mental health comorbidities associated with the odds of using tobacco and harmful levels of alcohol concurrently. DESIGN AND METHODS: Data were drawn from the 45 and Up Study, a large cohort study with 267 153 adults aged 45 years and over in New South Wales, Australia. Participants completed a survey assessing alcohol, smoking, psychological distress, treatment for depression and anxiety, and a range of socioeconomic status indicators. Univariate analyses and three multiple-logistic regression models were used to determine associations with (i) tobacco but not alcohol use; (ii) alcohol but not tobacco use; and (iii) concurrent tobacco and risky levels of alcohol use. RESULTS: Being female, younger, lower individual and area-level socioeconomic status (SES) and depression and psychological distress were associated with tobacco use alone. Factors associated with alcohol use alone were older age, male gender, higher SES, and lower psychological distress and no recent depression treatment. Factors associated with concurrent risky alcohol consumption and tobacco use included being 45-64, being male, less education, earning <$30 000, being employed, and living in lower-SES areas, treatment for depression, and high distress on the Kessler-10. DISCUSSION AND CONCLUSIONS: Results suggest strong links between SES, treatment for depression, psychological distress, and concurrent tobacco and alcohol use. This has implications for public health policies and clinical treatment for tobacco and alcohol use, suggesting greater emphasis on addressing multiple health and social concerns. [Bonevski B, Regan T, Paul C, Baker AL, Bisquera A. Associations between alcohol, smoking, socioeconomic status and comorbidities: Evidence from the 45 and Up Study. Drug Alcohol Rev 2014;33:169-176].


Subject(s)
Alcohol Drinking/epidemiology , Smoking/epidemiology , Stress, Psychological/epidemiology , Tobacco Use Disorder/epidemiology , Age Factors , Aged , Aged, 80 and over , Comorbidity , Female , Health Surveys , Humans , Male , Mental Health , Middle Aged , New South Wales , Sex Factors , Social Class
16.
Psychooncology ; 22(12): 2720-8, 2013 Dec.
Article in English | MEDLINE | ID: mdl-23801643

ABSTRACT

OBJECTIVE: A patient-centred approach to discussing life expectancy with cancer patients is recommended in Western countries. However, this approach to eliciting and meeting patient preferences can be challenging for clinicians. The aims of this study were the following: (i) to examine cancer patients' preferences for life expectancy disclosure; and (ii) to explore agreement between cancer patients' preferences for, and perceived experiences of, life expectancy disclosure. METHODS: Cancer patients undergoing radiotherapy treatment in metropolitan Australia completed a cross-sectional touchscreen computer survey including optional questions about their life expectancy disclosure preferences and experiences. RESULTS: Of the 208 respondents, 178 (86%) indicated that they would prefer their clinician to ask them before discussing life expectancy, and 30 (14%) indicated that they would prefer others (i.e. clinicians, family) to decide whether they were given life expectancy information. Of the 175 respondents who were classified as having a self- determined or other-determined disclosure experience, 105 (60%) reported an experience of life expectancy disclosure that was in accordance with their preferences. Cohen's κ was -0.04 (95% CI, -0.17, 0.08), indicating very poor agreement between patients' preferences for and perceived experiences of life expectancy disclosure (p = 0.74). CONCLUSIONS: In light of patient-centred prognosis disclosure guidelines, our findings of a majority preference for, and experience of, a self-determined approach to life expectancy disclosure amongst radiation oncology patients are encouraging. However, poor agreement between preferences and experiences highlights that additional effort from clinicians is required in order to achieve a truly patient-centred approach to life expectancy disclosure.


Subject(s)
Disclosure , Life Expectancy , Neoplasms/psychology , Patient Preference/psychology , Patient-Centered Care/methods , Physician-Patient Relations , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Neoplasms/mortality , Neoplasms/therapy , Outpatients , Patient Participation , Prognosis , Surveys and Questionnaires , Young Adult
17.
Aust N Z J Public Health ; 37(2): 118-23, 2013 Apr.
Article in English | MEDLINE | ID: mdl-23551469

ABSTRACT

OBJECTIVE: To examine the prevalence and clustering of six health risk behaviours (smoking, alcohol, inadequate sun protection, physical inactivity, and inadequate fruit and vegetable consumption) among severely disadvantaged individuals. METHODS: A cross-sectional touch screen computer survey was conducted with 383 clients attending a social and community welfare organisation in New South Wales. Participants were assessed on smoking status, alcohol consumption, fruit and vegetable consumption, physical activity, sun protection and socio-demographic characteristics. Descriptive statistics, factor analysis and logistic regression were used to assess the prevalence, clustering and socio-demographic predictors of health risk behaviours. RESULTS: Ninety-eight per cent of the participants reported inadequate vegetable consumption, 62.7% reported inadequate fruit consumption, 82.5% reported inadequate sun protection, 61.7% smoked tobacco, 51.4% consumed alcohol at risky levels and 36.5% were insufficiently active. Most participants (87%) reported three or more risk behaviours. Male participants, younger participants and those with lower education were more likely to smoke tobacco and consume alcohol. CONCLUSIONS: The prevalence of health risk behaviours among a sample of typically hard-to-reach, severely disadvantaged individuals is extremely high. IMPLICATIONS: Future intervention development should take into account the likelihood of health risk clustering among severely disadvantaged groups.


Subject(s)
Health Behavior , Risk-Taking , Social Welfare/ethnology , Vulnerable Populations/psychology , Adult , Alcohol Drinking/ethnology , Cluster Analysis , Cross-Sectional Studies , Diet , Female , Health Status , Health Surveys , Humans , Life Style , Logistic Models , Male , Middle Aged , New South Wales/epidemiology , Prevalence , Smoking/ethnology , Socioeconomic Factors , Surveys and Questionnaires , Vulnerable Populations/ethnology , Young Adult
18.
Drug Alcohol Rev ; 31(5): 698-708, 2012 Jul.
Article in English | MEDLINE | ID: mdl-22571783

ABSTRACT

ISSUES: Only a limited amount of research has been conducted to explore whether there are socioeconomic status differences in responses to mass media. However, the methodological quality of this evidence has not been assessed, limiting confidence in conclusions that can be drawn regarding study outcomes. A systematic review of the effectiveness of anti-tobacco mass media campaigns with socially disadvantaged groups was conducted, and the methodological quality of included studies was assessed. APPROACH: Medline, The Cochrane Library, PsycInfo, Embase and Web of Science were searched using MeSH and keywords for quantitative studies conducted in Western countries prior to March 2012. A methodological quality assessment and narrative analysis of included studies was undertaken. KEY FINDINGS: Seventeen relevant studies (reported in 18 papers) were identified; however, weak study designs and selection bias were common characteristics, limiting strong conclusions about effectiveness. Using predominantly non-cessation related outcome measures reviewed papers indicated mixed results for mass media tobacco control campaign effectiveness among various social groups. Most studies assessed mass media impact on low socioeconomic status groups rather than highly socially disadvantaged groups. IMPLICATIONS: Methodological rigour of evaluations in this field must be improved to aid understanding regarding the effectiveness of mass media campaigns in driving cessation among disadvantaged groups. CONCLUSION: The results of this review indicate a gap in methodologically rigorous research into the effectiveness of mass media campaigns among socially disadvantaged groups, particularly the highly disadvantaged.


Subject(s)
Mass Media , Smoking Cessation/methods , Smoking Prevention , Advertising/methods , Humans , Research/standards , Socioeconomic Factors
19.
Patient Educ Couns ; 88(1): 87-92, 2012 Jul.
Article in English | MEDLINE | ID: mdl-22296772

ABSTRACT

OBJECTIVE: This study aimed to examine preferred and perceived roles of haematological cancer survivors in treatment decision making. METHODS: Participants were within three years of diagnosis and registered with a cancer registry in one Australian state. 732 eligible survivors were invited to complete a paper and pencil survey. RESULTS: 268 survivors completed the survey (37% response rate). The majority of participants (46%) preferred a passive role in decision making. Thirty percent of participants preferred to make the decision in collaboration with the doctor, whereas 26% preferred an active role in decision making. Just over half of respondents (56%) reported an exact match between their preferred and perceived roles. Where discordance between preferred and perceived roles were identified, survivors were more likely to report having been more passively than actively involved compared to their preferred roles. CONCLUSION: There is considerable variation in haematological cancer survivors' preferred and perceived roles in treatment decision making. PRACTICE IMPLICATIONS: This study highlights the need to improve clinical communication to ensure that patient experiences align with their preferences for involvement in treatment decision making.


Subject(s)
Communication , Decision Making , Hematologic Neoplasms/psychology , Patient Participation , Patient Preference , Physician-Patient Relations , Survivors/psychology , Adolescent , Adult , Aged , Aged, 80 and over , Australia , Cooperative Behavior , Cross-Sectional Studies , Female , Health Care Surveys , Hematologic Neoplasms/therapy , Humans , Male , Middle Aged , Patient Satisfaction , Perception , Surveys and Questionnaires , Young Adult
20.
Support Care Cancer ; 20(2): 207-19, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22089430

ABSTRACT

PURPOSE: This review aimed to examine (a) trends in the number of publications on unmet needs over time and (b) the effectiveness of interventions designed to reduce unmet needs among cancer patients. METHODS: An electronic literature search of Medline to explore trends in the number of publications on patients' unmet needs and an additional literature search of Medline, CINAHL, PsychINFO, and Web of Science databases to identify methodologically rigorous research trials that evaluated interventions to reduce unmet needs were conducted. RESULTS: Publications per year on unmet needs have increased over time, with most being on descriptive research. Nine relevant trials were identified. Six trials reported no intervention effect. Three trials reported that intervention participants had a lower number of unmet needs or lower unmet needs score, compared to control participants. Of these, one study found that the intervention group had fewer supportive care needs and lower mean depression scores; one study found that intervention participants with high problem-solving skills had fewer unmet needs at follow-up; and one study found an effect in favor of the intervention group on psychological need subscale scores. CONCLUSIONS: Reasons for varying results across trials and the limited effectiveness of unmet needs interventions are more broadly discussed. These include inadequacies in psychometric rigor, problems with scoring methods, the use of ineffective interventions, and lack of adherence to intervention protocols.


Subject(s)
Health Services Needs and Demand , Needs Assessment , Neoplasms/psychology , Humans , Psychometrics , Research Design , Time Factors
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