1.
Chem Commun (Camb)
; 55(98): 14844-14847, 2019 Dec 05.
Article
in English
| MEDLINE
| ID: mdl-31768507
ABSTRACT
Ultrasmall sub-10 nm nanoparticles of Prussian blue analogues incorporating GdIII ions at their periphery revealed longitudinal relaxivities above 40 mM-1 s-1 per GdIII regardless of the nature of the core and the polymer coating. Large T1-weighted contrast enhancements were achieved in addition to a highly efficient photothermal effect and in vivo photoacoustic imaging in tumors.
Subject(s)
Ferrocyanides/chemistry , Magnetic Resonance Imaging/methods , Nanoparticles/chemistry , Theranostic Nanomedicine , Animals , Cell Line, Tumor , Contrast Media/chemistry , Gadolinium/chemistry , Humans , Mice , Neoplasms/diagnostic imaging , Transplantation, Heterologous
2.
Chem Commun (Camb)
; 50(51): 6740-3, 2014 Jun 28.
Article
in English
| MEDLINE
| ID: mdl-24829060
ABSTRACT
Large longitudinal relaxivities were observed in Mn(II)-containing Prussian blue analogue nanoparticles. At low concentrations and high field (7 T), a remarkable positive contrast enhancement was seen which exceeded that of clinical contrast agents and was attributed to the very large proportion of surface atoms of these coordination nanoparticles.