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1.
Ann R Coll Surg Engl ; 91(8): 637-40, 2009 Nov.
Article in English | MEDLINE | ID: mdl-19785938

ABSTRACT

INTRODUCTION: The aims of this study were to audit results of a 10-year experience of surgery for acute limb ischaemia (ALI) in terms of limb salvage and mortality rates, and to compare results with a historical published series from our unit. PATIENTS AND METHODS: All emergency operations performed during the period 1993-2003 were identified from theatre registers and patient notes reviewed to determine indications for, and outcome of, surgery. Data were compared to a similar cohort who underwent surgery from 1980 to 1990. RESULTS: There was a 33% increase in workload from 87 to 116 patients between the two time periods. The number of patients with idiopathic ALI reduced (24% versus 4%; P < 0.05), and there were fewer smokers (71% versus 39%; P < 0.05) and a greater number of claudicants (17% versus 35%; P < 0.05) in those treated from 1993-2003. Latterly, more patients underwent pre-operative heparinisation (33% versus 80%; P < 0.05), received prophylactic antibiotics (14% versus 63%; P < 0.05), and had anaesthetic presence in theatre (46% versus 88%; P < 0.05). There was also a reduction in local anaesthetic procedures (80% versus 41%; P < 0.05). Despite increased pre-operative (15% versus 47%; P < 0.05) and on-table imaging (0% versus 16%; P < 0.05) technical success did not improve. Whilst complication rates were identical at 62%, there were fewer cardiovascular complications in the recent cohort. The 30-day mortality rate for embolectomy fell from 45% to 33%. Multivariate analysis revealed age > 70 years, prolonged symptom duration, ASA score > or = III, lack of prophylactic antibiotics, absence of an anaesthetist, and operations performed under local anaesthetic to be associated with increased risk of mortality. Factors adversely affecting limb salvage included prolonged duration from symptom onset to operation, and a history of claudication or smoking. CONCLUSIONS: Despite improvements in pre- and peri-operative management, arterial embolectomy/thrombectomy remains a procedure with a high morbidity and mortality. Further attempts to improve outcome must be directed at early diagnosis and referral as delay from symptom onset to surgery is a major determinant of outcome.


Subject(s)
Embolectomy/mortality , Extremities/blood supply , Ischemia/surgery , Postoperative Complications/mortality , Acute Disease , Adult , Aged , Aged, 80 and over , Amputation, Surgical/mortality , Amputation, Surgical/statistics & numerical data , Embolectomy/adverse effects , Hospitals, District , Hospitals, General , Humans , Intermittent Claudication/epidemiology , Ischemia/epidemiology , Limb Salvage/statistics & numerical data , Medical Audit , Middle Aged , Smoking/epidemiology , Time Factors , Treatment Outcome , United Kingdom/epidemiology
2.
Int J Clin Pract ; 57(3): 245-6, 2003 Apr.
Article in English | MEDLINE | ID: mdl-12723734

ABSTRACT

A 45-year-old woman was admitted with a gangrenous toe. She had a pancreatico-renal transplant for end-stage renal disease due to type I insulin dependent diabetes three years previously and had been taking immunosuppressive agents. An epidural catheter was placed to relieve the rest pain. Next day she was found to be hypotensive and tachycardic along with other features of shock. She did not have any clinical symptoms and signs initially. Urgent blood investigations were normal except for Hb of 5.0 g/dl; an ultrasound scan showed free fluid in the peritoneal cavity. Emergency laparotomy after resuscitation confirmed a massive haemoperitoneum secondary to a ruptured spleen. Histology showed loss of areas of the capsule and other areas showing subcapsular haemorrhage with no underlying pathology in the spleen.


Subject(s)
Splenic Rupture/diagnosis , Female , Humans , Middle Aged , Rupture, Spontaneous/diagnosis
3.
Ann R Coll Surg Engl ; 84(3): 172-4, 2002 May.
Article in English | MEDLINE | ID: mdl-12092868

ABSTRACT

Rubber band ligation (RBL) is an effective treatment for symptomatic haemorrhoids but carries significant morbidity. We performed a prospective study of 98 consecutive patients treated by RBL in the out-patient clinic. Immediate, intermediate (within 2 weeks) and late (within 2 months) complications were recorded. Immediate complications occurred in 66 (67.3%) patients. Pain was the predominant symptom in 50 patients (51%). Fifteen (15.3%) patients had vasovagal attacks and 1 (1%) had bleeding. Twenty-five patients (25.5%) were unable to perform normal activities on the day of RBL. One patient needed hospital admission for control of pain. Seventy four (75.5%) patients would have RBL if they needed further treatment for haemorrhoids. Symptomatic cure was achieved in 71 patients (72.4%). RBL is an effective treatment but with significant complications. Patients should be adequately warned, especially of pain and vasovagal attacks.


Subject(s)
Hemorrhoids/therapy , Adult , Aged , Aged, 80 and over , Ambulatory Care/methods , Female , Hemorrhoids/complications , Humans , Ligation/methods , Male , Middle Aged , Pain/etiology , Prospective Studies , Rubber
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