ABSTRACT
Introduction Juvenile hemochromatosis is a rare but severe form of hereditary hemochromatosis that typically presents early in life and can be fatal if left untreated. Case presentation We present the case of a 30-year-old man with a clear symptomatology of juvenile hemochromatosis, but in whom the diagnosis was initially mistaken for alcoholic liver disease because of known excessive use of alcohol, with the consequence that an adequate treatment was postponed. Discussion In this report, we discuss the diagnosis and treatment of juvenile hemochromatosis, focusing on the interaction between hemochromatosis and alcohol induced liver disease and how to differentiate both. We conclude that every young patient with suspected alcoholic liver disease and signs of iron overload should have a testing to rule out other iron overloading pathology, since early recognition and treatment with phlebotomy may prevent organ damage and improve life expectancy.
Subject(s)
Cardiomyopathies , Hemochromatosis/congenital , Liver Cirrhosis , Adult , Cardiomyopathies/diagnosis , Cardiomyopathies/etiology , Diagnosis, Differential , Hemochromatosis/complications , Hemochromatosis/diagnosis , Hemochromatosis/therapy , Humans , Liver Cirrhosis/diagnosis , Liver Cirrhosis/etiology , Male , Time-to-TreatmentABSTRACT
Enterococcus cecorum septicemia is rare in humans. This case describes a man with underlying liver cirrhosis, a comorbidity that contributes to half of the E. cecorum infections described in the current literature. The patient was successfully treated with ceftriaxone. Identification of this species was accurately made with Matrix-Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometry and confirmed by 16S rDNA sequencing.
ABSTRACT
We will present the fourth case in the English-language literature of a mid-gestational colonoscopy-assisted manual reposition of an incarcerated uterus. Despite the ready availability of ultrasound, a great number of incarcerations are not recognized before term. Since early diagnosis is the key to a successful treatment, it is important that providers acquire prompt knowledge of this obstetric disorder. Magnetic Resonance Imaging has an important additional value to ultrasound in the detailed scanning of this potentially perilous condition.
Subject(s)
Magnetic Resonance Imaging , Pregnancy Complications/pathology , Pregnancy Complications/therapy , Uterine Retroversion/pathology , Uterine Retroversion/therapy , Adult , Female , Humans , Musculoskeletal Manipulations , Pregnancy , Pregnancy Complications/diagnostic imaging , Sigmoidoscopy , Ultrasonography , Uterine Retroversion/diagnostic imagingSubject(s)
Collateral Circulation , Hepatic Encephalopathy/pathology , Mesenteric Veins/pathology , Vena Cava, Inferior/pathology , Anti-Bacterial Agents/therapeutic use , Fatty Liver/complications , Fatty Liver/pathology , Fatty Liver/physiopathology , Female , Gastrointestinal Agents/therapeutic use , Hepatic Encephalopathy/drug therapy , Hepatic Encephalopathy/etiology , Humans , Lactulose/therapeutic use , Mesenteric Veins/physiopathology , Middle Aged , Norfloxacin/therapeutic use , Treatment Outcome , Vena Cava, Inferior/physiopathologyABSTRACT
The standard adjuvant therapy for rectal cancer is 5-fluorouracil (5-FU) often combined with radiotherapy. Well-documented side effects of 5-FU include nausea, vomiting and diarrhoea, leukopenia and thrombocytopenia, hand-foot syndrome, mucositis, and cardiotoxicity. Peripheral neurotoxicity has only rarely been reported. We report a patient with a stage II rectal carcinoma who developed a mild axonal sensorimotor neuropathy at the end of a 5-FU therapy.
