ABSTRACT
An assessment is carried out of the results obtained in the Constantza County after over 2 years of application of the "3 + 6" regimens (INH + RMP and INH + SM + EMB) in a group of 119 patients with initially bacteriologically confirmed pulmonary tuberculosis. The standard regimens applied were not replaced with other regimens. The dynamics of negativation in cultures confirmed that over 50% of the patients had become negative after the first month of treatment. For practical purposes negativation was completed before 3 months in all the cases. The only two failures were recorded in the first three months after the treatment was ended. No re-positivation was noted in the second year of the follow-up. A stable resolution was achieved in 98% of the patients.
Subject(s)
Antitubercular Agents/administration & dosage , Tuberculosis, Pulmonary/drug therapy , Adolescent , Adult , Aged , Antitubercular Agents/therapeutic use , Drug Therapy, Combination , Humans , Middle AgedABSTRACT
The study of aspects of integration of chemotherapy during the initial stages of the anti-tuberculous treatment, carried out in 15 rural medical circumscriptions in the Constantza and mpedgidia anti-tuberculous dispensaries, has demonstrated the applicability of standardized chemotherapy schemes at the level of general practice network. The personnel working in the frame of this network showed considerable interest and preoccupation with the optimal achievement of the strictly supervised treatment. The results of bacteriological controls (direct BK examination and cultures), indicated that in 97,4% of the cases these results are maintained negative in patients that could be evaluated. An assessment of this action revealed that the indices showing the incorporation of patients in the strictly supervised treatment as well as the regularity of the administration have been very good.
