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Eur J Pharm Sci ; 21(2-3): 115-8, 2004 Feb.
Article in English | MEDLINE | ID: mdl-14757482

ABSTRACT

Various N-alkyl and N-acyl derivatives of 2-(4-thiazolyl)-1H-benzimidazole, an anthelmintic and systemic fungicide, were synthesized by polymer-supported reactions and screened for their antifungal and antibacterial potency to establish structure-activity relationships.


Subject(s)
Anti-Bacterial Agents/pharmacology , Antifungal Agents/pharmacology , Thiabendazole/analogs & derivatives , Thiabendazole/pharmacology , Alternaria/drug effects , Anti-Bacterial Agents/chemical synthesis , Antifungal Agents/chemical synthesis , Aspergillus/drug effects , Bacillus/drug effects , Fusarium/drug effects , Microbial Sensitivity Tests , Polymers/chemistry , Pseudomonas/drug effects , Structure-Activity Relationship , Thiabendazole/chemical synthesis
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