ABSTRACT
OBJECTIVE: To determine the prognostic accuracy of biochemical, clinical, electrophysiological, and neuropsychological investigations in predicting outcomes after cardiac arrest. DESIGN: Prospective study. SETTING: Intensive care unit of the Hamburg-Eppendorf University Medical Center, Hamburg, Germany. PATIENTS: A total of 80 patients (mean age, 63.79 +/- 15.85 yrs) after cardiopulmonary resuscitation. INTERVENTIONS: Serial blood samples (days 2-4), clinical examinations (days 2 and 4), sensory-evoked potentials (day 4), and neuropsychological assessments (Subject(s)
Cardiopulmonary Resuscitation
, Evoked Potentials, Somatosensory
, Heart Arrest/therapy
, Nerve Growth Factors/blood
, Neuropsychological Tests
, Phosphopyruvate Hydratase/blood
, S100 Proteins/blood
, Adolescent
, Adult
, Aged
, Aged, 80 and over
, Biomarkers/blood
, Coma
, Female
, Heart Arrest/blood
, Heart Arrest/physiopathology
, Humans
, Logistic Models
, Male
, Middle Aged
, Multivariate Analysis
, Prognosis
, Proportional Hazards Models
, Prospective Studies
, ROC Curve
, S100 Calcium Binding Protein beta Subunit
, Sensitivity and Specificity
, Treatment Outcome