ABSTRACT
Purpose: To evaluate the effect of age, sex, body mass index (BMI), and baseline blood count on the final composition of platelet rich-plasma (PRP) and to evaluate the variability of PRP applied in the same patient at 2 different times. Methods: Potential subjects treated with PRP between January 2019 and December 2021 were identified in an institutional registry. Patient demographics and baseline blood count were prospectively recorded in a consecutive series of patients treated with PRP for a musculoskeletal condition in our Institution. The influence of sex, BMI, age, and baseline blood count on final platelet concentrations in PRP was evaluated. Finally, intrapersonal variability was evaluated. Results: A total of 403 PRP injections from 357 patients were analyzed from an institutional prospective registry of PRP between January 2019 and December 2021. A directly proportional variation in PRP platelet count of 3.8× was observed for each unit increase in baseline blood platelet count. For every decade increase, we observed an approximate decrease of 32,666 platelets. When the first dose of PRP platelet counts was compared with the second dose of PRP platelet counts between the same patients, significant differences were found. A mean of 890,018 platelets in the first PRP and a mean of 1,244,467 in the second PRP with a mean difference of 354,448 was found (P = .008). We did not find differences in the final concentration of platelets regarding sex, BMI, or PRP protocol. Conclusions: Overall the final composition of PRP (platelet count) was significantly influenced by patient's age and baseline platelet count. In contrast, BMI, sex and the rest of the components of the baseline blood count did not have a significant influence on final PRP. Furthermore, in patients who received 2 doses of PRP, the final concentration of platelets varied significantly between the 2 preparations. Level of Evidence: Level IV, prognostic case series.
ABSTRACT
INTRODUCTION: Anterior cruciate ligament (ACL) reconstruction is a "daily" surgery. Nevertheless, pretibial cyst formation is a very rare complication and may appear years after the reconstruction. Even more infrequent is the recurrence of this complication. CASE REPORT: We present a patient who developed a pretibial cyst 44 months after an ACL reconstruction and who underwent three open surgeries due to recurrence. Up to date, there are no symptoms or signals of cyst recurrence after 18 months of follow-up. CONCLUSION: Initial surgical resection might have failed due to insufficient surgical treatment. In case of suspicion of articular communication, we consider that the correct treatment is the resection of the cyst, proper curettage of the tunnel walls and a thorough filling of the space with bone graft. This course oftreatment may avoid a recurrence.
