Redes sociais institucionais frente à infodemia causada pela covid-19: uma análise das interações dos usuários / Institutional social networks against the infodemia caused by covid-19: an analysis of user interactions / Redes sociales institucionales ante la infodemia provocada por covid-19: un análisis de las interacciones de los usuários

Objetivo: Analisar a interação dos usuários em publicações de saúde com informações sobre covid-19 nas redes sociais da Prefeitura Municipal de Macapá (capital do estado do Amapá). Métodos: Trata-se de uma pesquisa de abordagem qualitativa, do tipo descritivo-exploratório, realizada com os usuários que interagiram com as publicações sobre covid-19 das redes sociais do Facebook, Instagram e Twitter da Prefeitura de Macapá. A coleta de dados ocorreu através de entrevista semiestruturada e os dados foram analisados por meio da análise de conteúdo de Bardin. Resultados: Com base nos discursos dos participantes, emergiram quatro categorias: 1 - Importância de informação clara e de fácil compreensão para todos os tipos de público; 2 - O compartilhamento de informações nas redes sociais como incentivo à prevenção; 3 - A responsabilidade de checar as informações nas redes sociais de fontes não oficiais; e 4 - A comunicação como uma via de mão dupla: postagem e resposta. Conclusão: As redes sociais institucionais podem ser um importante espaço para a disseminação de informações relacionadas à covid-19, porém se torna necessário qualificar o trabalho dessas redes através de estratégias que articulem a gestão destas em todos os âmbitos. (AU)

Objective: To analyze the interaction of users in publications of health with informations about covid-19 in Macapá's city hall (capital of the state of Amapá) social media. Methods: It is about a qualitative approach research, exploratory-descriptive type, performed with users that interacted with publications about covid-19 at this social medias: Facebook, Instagram and Twitter's city hall. The data collection occurred through semi-structured interviews and the data were analyzed through the Bardin' content analysis. Results: Based on the participants' speeches, four categories emerged: 1 - Importance of clear and easy-to-understand information for all types of public; 2 - Sharing information on social networks as an incentive for prevention; 3 - The responsibility to check information on social networks from unofficial sources; and 4 - Communication as a two-way street: post and reply. Conclusion: The institutional social medias are able to be an important space for the dissemination of information related to covid-19, however, it becomes necessary to qualify the work of those networks through strategies that can articulate better with the management of those in the whole sphere. (AU)

Objetivo: Analizar la interacción de los usuarios de publicaciones de salud con información sobre covid-19 en las redes sociales del Municipio de Macapá (capital del estado de Amapá). Métodos: Se trata de una investigación cualitativa, de tipo descriptiva-exploratoria, realizada con usuarios que interactuaron con las publicaciones sobre covid-19 de las redes sociales de Facebook, Instagram y Twitter del Municipio de Macapá. La recolección de datos ocurrió a través de entrevistas semiestructuradas y los datos fueron analizados utilizando el análisis de contenido de Bardin. Resultados: Con base en los discursos de los participantes, surgieron cuatro categorías: 1 - Importancia de la información clara y fácil de entender para todo tipo de público; 2 - Compartir información en las redes sociales como incentivo para la prevención; 3 - La responsabilidad de verificar la información en las redes sociales de fuentes no oficiales; y 4 - La comunicación como vía de doble sentido: post y respuesta. Conclusión: Las redes sociales institucionales pueden ser un espacio importante para la difusión de información relacionada con Covid-19, sin embargo, se hace necesario capacitar el trabajo de estas redes a través de estrategias que articulen su gestión en todos los ámbitos. (AU)

Work and Mental Distress among Nurses in the Amazon Region of Brazil during the COVID-19 Pandemic.

OBJECTIVE: To assess the relationship between psychopathological symptoms and the social, clinical, and occupational profile of nurses in the Amazon region of Brazil during the COVID-19 pandemic. METHODS: A descriptive cross-sectional online study was conducted in 2020 with 261 nurses. The Symptom Assessment Scale-40 was utilized. RESULTS: The presence of pre-existing conditions before the pandemic was associated with psychotism (p=0.044). Experiencing constraints and/or violence at work during the pandemic was associated with somatization (p=0.025), and working hours were associated with anxiety (p=0.025). Nurses predominantly exhibited symptoms related to fear (33.7%), tension (34.5%), and a sense that something is wrong in the mind (22.6%). CONCLUSIONS: A significant association was observed between working hours and anxiety symptoms, the experience of constraints and/or violence at work during the COVID-19 pandemic and somatization symptoms, as well as between pre-existing conditions and psychotism symptoms related to COVID-19.

Retrospective pharmacogenetic study in a cohort of pediatric tuberous sclerosis complex patients using everolimus.

Aim: Tuberous sclerosis complex (TSC) is a rare disease that produces multisystemic disorders. Everolimus (EVR) is the only immunosuppressive drug approved to control the symptoms and progression of the disease. The aim was to evaluate the genotype-phenotype association to improve the pediatric TSC pharmacotherapeutic outcome. Patients & methods: Ten pediatric TSC patients were recruited. Concomitant treatment and main metabolic enzymes and transporter coding gene variants of EVR were analyzed. Results: Significant associations were found between CYP3A4*22 allele and concomitant treatment with valproic acid (CYP3A4-inhibitor) with a poor metabolizer phenotype and the presence of pneumonia. Conclusion: This is the first pharmacogenetic study of EVR in pediatric TSC patients. The authors propose to consider concomitant treatment and pharmacogenetics due to their multifactorial status.

Screening for late-onset Pompe disease in Internal Medicine departments in Spain.

BACKGROUND: The screening of high-risk populations using dried blood spots (DBS) has allowed the rapid identification of patients with Pompe disease, mostly in Neurology departments. The aim of the study was to determine the prevalence of late-onset Pompe disease (LOPD) among patients not previously diagnosed or tested for this entity despite presenting possible signs or symptoms of the disease in Internal Medicine departments in Spain. METHODS: This epidemiological, observational, cross-sectional, multicenter study included a single cohort of individuals with clinical suspicion of LOPD seen at Internal Medicine departments in Spain. The diagnosis of LOPD was initially established on the basis of the result of DBS. If decreased enzyme acid-alpha-1,4-glucosidase (GAA) activity was detected in DBS, additional confirmatory diagnostic measurements were conducted, including GAA activity in lymphocytes, fibroblasts, or muscle and/or genetic testing. RESULTS: The diagnosis of LOPD was confirmed in 2 out of 322 patients (0.6%). Reasons for suspecting LOPD diagnosis were polymyositis or any type of myopathy of unknown etiology (in one patient), and asymptomatic or pauci-symptomatic hyperCKemia (in the other). The time between symptom onset and LOPD diagnosis was 2.0 and 0.0 years. Both patients were asymptomatic, with no muscle weakness. Additionally, 19.7% of the non-LOPD cases received an alternative diagnosis. CONCLUSIONS: Our study highlights the existence of a hidden population of LOPD patients in Internal Medicine departments who might benefit from early diagnosis and early initiation of potential treatments.

Development of frequency tuning shaped by spatial cue reliability in the barn owl's auditory midbrain.

Sensory systems preferentially strengthen responses to stimuli based on their reliability at conveying accurate information. While previous reports demonstrate that the brain reweighs cues based on dynamic changes in reliability, how the brain may learn and maintain neural responses to sensory statistics expected to be stable over time is unknown. The barn owl's midbrain features a map of auditory space where neurons compute horizontal sound location from the interaural time difference (ITD). Frequency tuning of midbrain map neurons correlates with the most reliable frequencies for the neurons' preferred ITD (Cazettes et al., 2014). Removal of the facial ruff led to a specific decrease in the reliability of high frequencies from frontal space. To directly test whether permanent changes in ITD reliability drive frequency tuning, midbrain map neurons were recorded from adult owls, with the facial ruff removed during development, and juvenile owls, before facial ruff development. In both groups, frontally tuned neurons were tuned to frequencies lower than in normal adult owls, consistent with the change in ITD reliability. In addition, juvenile owls exhibited more heterogeneous frequency tuning, suggesting normal developmental processes refine tuning to match ITD reliability. These results indicate causality of long-term statistics of spatial cues in the development of midbrain frequency tuning properties, implementing probabilistic coding for sound localization.

Work and Mental Distress among Nurses in the Amazon Region of Brazil during the COVID-19 Pandemic / Trabajo y malestar mental entre las enfermeras en la región amazónica de Brasil durante la pandemia de COVID-19 / Trabalho e sofrimento mental dos enfermeiros da Região Amazônica do Brasil durante a pandemia de COVID-19

ABSTRACT Objective: To assess the relationship between psychopathological symptoms and the social, clinical, and occupational profile of nurses in the Amazon region of Brazil during the COVID-19 pandemic. Methods: A descriptive cross-sectional online study was conducted in 2020 with 261 nurses. The Symptom Assessment Scale-40 was utilized. Results: The presence of pre-existing conditions before the pandemic was associated with psychotism (p=0.044). Experiencing constraints and/or violence at work during the pandemic was associated with somatization (p=0.025), and working hours were associated with anxiety (p=0.025). Nurses predominantly exhibited symptoms related to fear (33.7%), tension (34.5%), and a sense that something is wrong in the mind (22.6%). Conclusions: A significant association was observed between working hours and anxiety symptoms, the experience of constraints and/or violence at work during the COVID-19 pandemic and somatization symptoms, as well as between pre-existing conditions and psychotism symptoms related to COVID-19.

RESUMEN Objetivo: Evaluar la relación entre los síntomas psicopatológicos y el perfil social, clínico y ocupacional de las enfermeras en la región amazónica de Brasil durante la pandemia de COVID-19. Métodos: Se llevó a cabo un estudio descriptivo transversal en línea en 2020 con la participación de 261 enfermeras. Se utilizó la Escala de Evaluación de Síntomas-40. Resultados: Se encontró una asociación significativa entre la presencia de condiciones preexistentes antes de la pandemia y el psicoticismo (p=0,044). Experimentar restricciones y/o violencia en el trabajo durante la pandemia se asoció con la somatización (p=0,025), y las horas de trabajo se relacionaron con la ansiedad (p=0,025). En general, las enfermeras presentaron predominantemente síntomas relacionados con el miedo (33,7%), la tensión (34,5%) y la sensación de que algo no está bien en la mente (22,6%). Conclusiones: Se observó una asociación significativa entre las horas de trabajo y los síntomas de ansiedad, así como entre la experiencia de restricciones y/o violencia laboral durante la pandemia de COVID-19 y los síntomas de somatización. Además, se encontró una asociación entre las condiciones preexistentes y los síntomas de psicoticismo relacionados con COVID-19.

RESUMO Objetivo: Avaliar a relação entre sintomas psicopatológicos e o perfil social, clínico e laboral dos enfermeiros da região Amazônica do Brasil durante a pandemia de COVID-19. Métodos: Realizou-se um estudo descritivo de corte transversal online com 261 enfermeiros em 2020. Utilizou-se a Escala de Avaliação de Sintomas-40. Resultados: A presença de doenças preexistentes à pandemia associou-se ao psicoticismo (p=0,044). Ter sofrido constrangimentos e/ou violências no trabalho durante a pandemia associou-se à somatização (p=0,025), e a carga horária de trabalho associou-se à ansiedade (p=0,025). Os enfermeiros manifestaram principalmente sintomas relacionados ao medo (33,7%), tensão (34,5%) e sensação de que algo está errado na mente (22,6%). Conclusões: Foi observada uma associação significativa entre a carga horária de trabalho e sintomas de ansiedade, o sofrimento de constrangimentos e/ou violências durante o trabalho no contexto da pandemia de COVID-19 e sintomas de somatização, bem como entre doenças preexistentes à COVID-19 e sintomas de psicoticismo.

Construção e validação de tecnologia educacional sobre insulinoterapia: estudo metodológico / Construction and validation of educational technology on insulin therapy: methodological study / Construcción y validación de tecnología educativa sobre insulinoterapia: estudio metodológico

RESUMO Objetivo: construir e validar tecnologia educacional sobre insulinoterapia para práticas educativas de profissionais de saúde. Método: estudo metodológico realizado em três etapas: construção, entre os meses de maio a setembro de 2019; e validação de conteúdo e validação de aparência, agosto de 2020 a agosto de 2021, em Universidade Pública do Amapá, Brasil. A validação de conteúdo e a validação de aparências foram realizadas em etapas únicas com 16 profissionais da área da saúde e com cinco profissionais de outras áreas respectivamente. Resultados: a tecnologia educacional foi nomeada álbum seriado sobre Insulinoterapia, estando disponível no formato impresso. Apresentou Índice de Validade de Conteúdo de 0,91 e Índice de Validade de Aparência de 1,00. Conclusão: a tecnologia foi validada e pode ser utilizada por profissionais de saúde da atenção primária em práticas educativas em saúde, com vistas à promoção de ensino-aprendizagem sobre o uso de insulina, beneficiando o processo de cuidado e comunicação na atenção à saúde.

ABSTRACT Objective: to build and validate educational technology on insulin therapy for educational practices of health professionals. Method: methodological study conducted in three stages: construction, between May and September 2019; and content validation and appearance validation, August 2020 to August 2021, in a Public University of Amapá, Brazil. Content validation and appearance validation were performed in single steps with 16 health professionals and with five professionals from other areas respectively. Results: The educational technology was named Serial Album on Insulin Therapy and was available in printed format. It presented a Content Validity Index of 0.91 and an Appearance Validity Index of 1.00. Conclusion: the technology was validated and can be used by primary care health professionals in health educational practices, with a view to promoting teaching-learning about the use of insulin, benefiting the process of care and communication in health care.

RESUMEN Objetivo: construir y validar una tecnología educativa sobre la insulinoterapia para las prácticas educativas de los profesionales de la salud. Método estudio metodológico realizado en tres etapas: construcción, entre mayo y septiembre de 2019; y validación de contenido y validación de apariencia, agosto de 2020 a agosto de 2021, en una Universidad Pública de Amapá, Brasil. La validación del contenido y la validación de la apariencia se realizaron en un solo paso con 16 profesionales de la salud y cinco profesionales de otras áreas, respectivamente. Resultados: la tecnología educativa se ha convertido en un rotafolio sobre insulinoterapia, disponible en formato impreso. Presentó un Índice de Validez de Contenido de 0,91 y un Índice de Validez de Apariencia de 1,00. Conclusión: la tecnología fue validada y puede ser utilizada por los profesionales de salud de la atención primaria en prácticas educativas en salud, con vistas a promover la enseñanza-aprendizaje sobre el uso de la insulina, beneficiando el proceso de atención y comunicación en salud.

Current clinical spectrum of common variable immunodeficiency in Spain: The multicentric nationwide GTEM-SEMI-CVID registry.

Common variable immunodeficiency (CVID) constitutes a heterogenic group of primary immunodeficiency disorders with a wide-ranging clinical spectrum. CVID-associated non-infectious morbidity constitutes a major challenge requiring a full understanding of its pathophysiology and its clinical importance and global variability, especially considering the broad clinical, genetic, and regional heterogeneity of CVID disorders. This work aimed to develop a nationwide, multicenter, retrospective study over a 3-year period describing epidemiological, clinical, laboratory, therapeutic, and prognostic features of 250 CVID patients in Spain. The mean diagnostic delay was around 10 years and most patients initially presented with infectious complications followed by non-infectious immune disorders. However, infectious diseases were not the main cause of morbimortality. Non-infectious lung disease was extraordinarily frequent in our registry affecting approximately 60% of the patients. More than one-third of the patients in our cohort showed lymphadenopathies and splenomegaly in their follow-up, and more than 33% presented immune cytopenias, especially Evans' syndrome. Gastrointestinal disease was observed in more than 40% of the patients. Among biopsied organs in our cohort, benign lymphoproliferation was the principal histopathological alteration. Reaching 15.26%, the global prevalence of cancer in our registry was one of the highest reported to date, with non-Hodgkin B lymphoma being the most frequent. These data emphasize the importance of basic and translational research delving into the pathophysiological pathways involved in immune dysregulation and diffuse lymphocytic infiltration. This would reveal new tailored strategies to reduce immune complications, and the associated healthcare burden, and ensure a better quality of life for CVID patients.

Los bosques estacionalmente secos del Perú: un re-análisis de sus patrones de diversidad y relaciones florísticas

Los bosques estacionalmente secos en el Perú constituyen un conjunto de ecosistemas que incluye tres grandes grupos florísticos: bosques costeros, interandinos y orientales. Con la excepción de los bosques estacionalmente secos de las llanuras costeras del norte del país, hasta hace poco la ausencia de datos hacía difícil describir adecuadamente estos grupos en base a su florística. En los últimos 20 años, en estos bosques se han generado diversos estudios florísticos e inventarios botánicos enfocados en plantas leñosas, que han llenado vacíos de conocimiento en áreas críticas. Con estos estudios hemos generado la base de datos DRYFLOR Perú que a la fecha incluye 526 inventarios cuantitativos (listas de especies en áreas discretas incluyendo registros de sus abundancias) y que nos permiten confirmar la distinción florística de los tres grandes grupos. Adicionalmente logramos reconocer claramente dos subgrupos de bosques estacionalmente secos costeros (de llanura y de montaña), dos subgrupos interandinos (valles del Marañón-Mantaro y del Pampas) y tres subgrupos orientales (valles del Huallaga, Tambo y Urubamba). Todos los subgrupos tienen un ensamblaje de especies de plantas leñosas que los distingue y caracteriza en términos de abundancia, frecuencia, riqueza de especies y niveles de endemismo. Si bien ahora podemos describir mejor la heterogeneidad florística de los bosques estacionalmente secos en el Perú, hemos identificado vacíos de conocimiento importantes que requieren de atención prioritaria: i) requerimos de esfuerzos de inventario adicionales en los bosques orientales, ii) necesitamos resolver las afinidades florísticas de los bosques del valle del Apurímac, iii) nuestros datos coinciden en poco más del 75% con las definiciones y distribución de bosques secos del reciente Mapa Nacional de Ecosistemas del Perú, y será necesario revisar el concepto de bosque estacionalmente seco para lograr capturar adecuadamente su distribución en este instrumento de gestión.

Seasonally dry forests in Peru are a combination of ecosystems that include three large floristic groups: coastal, inter-Andean and eastern forests. Except for the seasonally dry forests of the northern coastal plains of the country, until recently it was difficult to explore what occurred floristically within each group due to lack of data. However, in the last 20 years various floristic studies and botanical inventories focused on woody plants have managed to fill knowledge gaps in critical areas. With these studies we have generated the DRYFLOR Peru database that to date includes 526 quantitative inventories (lists of species in discrete areas, including records of their abundances) and that allows us to confirm the floristic distinction of the three large groups. Additionally, we were able to clearly recognize two subgroups of seasonally dry coastal forests (on coastal plains and along the Andean piedmont), two inter-Andean subgroups (within the Marañón-Mantaro and Pampas valleys) and three eastern subgroups (within the Huallaga, Tambo and Urubamba valleys). All subgroups have an assemblage of woody plant species that distinguishes and characterizes them in terms of abundance, frequency, species richness, and levels of endemism. Although we can now better describe the floristic heterogeneity of seasonally dry forests in Peru, we have identified important knowledge gaps that require urgent attention: i) we require additional inventory efforts in the eastern forests, ii) we need to resolve the floristic affinities of the forests of the Apurímac valley, iii) our data agree in little more than 75% with the definitions and distribution of dry forests of the recent National Ecosystem Map of Peru, and it will be necessary to review the concept of seasonally dry forests to adequately capture its distribution in this management tool.

COVID-19 and the Mental Health of Nursing Professionals in Brazil: Associations between Social and Clinical Contexts and Psychopathological Symptoms.

The COVID-19 pandemic has had an important negative psychological impact on people worldwide, especially nursing professionals who seem to be more vulnerable to the development of psychopathological symptoms. Objective: To analyze relationships between variables from the social and clinical contexts with psychopathological symptoms in nursing professionals from different geographic regions of Brazil during the COVID-19 pandemic. Methods: Cross-sectional study carried out with 1737 nursing professionals from the five regions of Brazil. Data collection was carried out online with a questionnaire made available via Google Forms containing sociodemographic, occupational, and clinical questions, and the Symptom Assessment Scale-40-R, for the assessment of psychopathological symptoms. Differences between mean scores for the severity of psychopathological symptoms were assessed using the Mann-Whitney and Kruskall-Wallis tests. Results: There was a significant difference in the psychoticism domain scores according to Brazilian geographic region, with greater severity among professionals from the North and Northeast regions when compared with those from the South region. Social context variables (gender, age group, and marital status) and clinical variables (psychological and psychiatric follow-up; psychological or emotional support by the institution; family member, friend, neighbor, or co-worker with COVID-19, and death among them; use of psychiatric medication without a medical prescription; and taking steps to take care of their mental health) were significantly related to psychopathological symptoms. Conclusions: The results point to the importance of mental health promotion strategies for professionals through psychological or emotional support, as evidence indicates that this support can be a predictor of reduced psychological distress.

Bem-Estar Subjetivo e Autoestima de pessoas em tratamento hemodialítico / Subjective well-being and self-esteem of people undergoing hemodialysis

A Doença Renal Crônica é progressiva e permanente, ocasiona perdas funcionais e interferências psicológicas que culminam sob o desgaste pessoal e implicam na modificação do cotidiano. O objetivo deste estudo foi avaliar os níveis de bem-estar subjetivo e autoestima de pessoas em tratamento hemodialítico, e identificar a relação entre esses construtos. Estudo quantitativo transversal, envolvendo 152 pessoas, em um Centro de Nefrologia. Os dados foram recolhidos utilizando questionário sociodemográfico, as Escalas de Bem-Estar Subjetivo e Autoestima. Para o estudo da associação do bem-estar subjetivo com a autoestima foi aplicado o Coeficiente de Correlação de Pearson; para associação com as variáveis sociodemográficas foram aplicados os testes estatísticos: Teste T de Student; Análise da Variância, Coeficiente de Correlação de Spearman. Houve predomínio do sexo masculino (65,1%), média de idade 55,3 (±13,6), casados (36,2%) com renda familiar de 1 a 5 salários mínimos e ensino médio completo (36,9%). Em relação ao Bem-estar subjetivo, constatou-se nível satisfatório de afetos positivos e baixa expressão de afetos negativos e maior nível de satisfação com a vida. O escore médio da autoestima foi de 29,63, indicando índices satisfatórios e correlações significativas. Constatou-se uma correlação positiva forte, significativa e proporcional, quanto maior o bem-estar subjetivo da pessoa, maior foi autoestima, e identificaram a associação com sexo, idade, estado civil, renda familiar e grau de escolaridade. A renda familiar apresentou relação com todas as dimensões dos construtos.

Chronic Kidney Disease is progressive and permanent, causing functional losses and psychological interference that culminate under personal exhaustion and imply a change in daily life. The objective of the study was to assess the levels of subjective well-being and self-esteem of people undergoing hemodialysis, and to identify the relationship between these constructs. This was a cross-sectional quantitative study, involving 152 people, in a Nephrology Center. Data were collected using a sociodemographic survey and the Subjective Well-Being and Self-Esteem Scales, respectively. Pearson's Correlation Coefficient was applied to study the association of subjective well-being with self-esteem; for association with sociodemographic variables, the following statistical tests were applied: Student's T test; Analysis of Variance, Spearman's Correlation Coefficient. There was a predominance of males (65.1%), average age 55.3 years old (± 13.6), married (36.2%) with a family income of 1 to 5 minimum wages, and complete high school education (36.9%). In relation to subjective well-being, there was a satisfactory level of positive feelings, and low expression of negative feelings, and a higher level of satisfaction with life. The average self-esteem score was 29.63, indicating satisfactory indices and significant correlations. A strong, significant, and proportional positive correlation was found. The greater the person's subjective well-being, the greater their self-esteem was, and an association with sex, age, marital status, family income, and education level was identified. Family income was related to all dimensions of the constructs.

"Descomplica, Dona Bete": construção de aplicativo sobre prevenção de complicações agudas do Diabetes Mellitus / "Descomplica, dona Bete": construction of application on prevention of acute complications of diabetes mellitus

Objetivo: construir aplicativo para educação em saúde de pessoas com Diabetes Mellitus sobre prevenção de complicações agudas da doença. Métodos: Estudo metodológico aplicado, exploratório, fase de produção tecnológica. Produção do aplicativo ocorreu em duas etapas: revisão de literatura; construção do aplicativo. Resultados: Revisão: identificou-se 13 estudos. Na produção do aplicativo "Descomplica, Dona Bete", optou-se pela construção em mídia, texto e áudio, com tela inicial de boas-vindas e tela secundária que direciona aos tópicos sobre prevenção das complicações agudas Hipoglicemia, Hiperglicemia, Cetoacidose Diabética e Estado Hiperglicêmico Hiperosmolar. Conclusão: o processo de construção do aplicativo baseado em evidências da literatura foi o primeiro passo para suprir parte de uma lacuna, considerando o déficit de conhecimento de pessoas diabéticas acerca das complicações agudas da doença. Portanto, constitui um suporte interativo para ações de educação em saúde com potencialidade para incentivar pessoas com diabetes a aprimorar o autocuidado preventivo. (AU)

Objective: To build an application for health education of people with Diabetes Mellitus on prevention of acute complications of the disease. Methods: Applied, exploratory methodological study, technological production phase. Application production took place in two stages: literature review; building the application. Results: 13 studies were identified. In the production of the application "Descomplica, Dona Bete", we opted for the construction in media, text and audio, with a welcome initial screen and a secondary screen that directs to topics on prevention of acute complications Hypoglycemia, Hyperglycemia, Diabetic Ketoacidosis and Status Hyperglycemic Hyperosmolar. Conclusion: The process of building the application based on evidence from the literature was the first step to fill part of a gap, considering the lack of knowledge of diabetic people about the acute complications of the disease. Therefore, it constitutes an interactive support for health education actions with the potential to encourage people with diabetes to improve preventive self-care. (AU)

Objetivo: Desarrollar una aplicación para la educación sanitaria de las personas con diabetes mellitus sobre la prevención de complicaciones agudas de la enfermedad. Métodos: Estudio metodológico exploratorio aplicado, fase de producción tecnológica. La producción de la aplicación se produjo en dos etapas: revisión de la literatura; construyendo la aplicación. Resultados: Revisión: se identificaron 13 estudios. En la producción de la aplicación "Descomplica, Dona Bete", elija construir en medios, texto y audio, con una pantalla de inicio de bienvenida y una pantalla secundaria que lo dirija a respuestas sobre complicaciones de complicaciones agudas Hipoglucemia, hiperglucemia, cetoacidosis diabética y estado hiperglucémico Hiperosmolar. Conclusión: El proceso de construcción de la aplicación basada en la literatura fue el primer paso para llenar un vacío, considerando la falta de conocimiento de las personas diabéticas sobre las complicaciones agudas de la enfermedad. Por lo tanto, ofrecer apoyo interactivo para acciones de educación en salud con el potencial de alentar a las personas con diabetes a mejorar o prevenir el autocuidado. (AU)

Resiliência de pessoas com Diabetes Mellitus após cirurgia de amputação / Resilience people with mellitus diabetes after amputation surgery

Objetivo:Identificar as características de resiliência de pessoas com DM após cirurgia de amputação, e a relação entre as características identificadas e o tempo de amputação. Metodologia: Estudo descritivo, transversal, de abordagem quantitativa, realizado em um hospital de emergência, envolvendo 80 pessoas. Foram utilizados questionário sociodemográfico para caracterização da amostra e a Escala de Resiliência para Adultos. No estudo de relação, foi aplicado o Teste de Correlação de Spearman. Resultados: Predomínio do sexo masculino, média de idade (58±10,4), casados, etnia parda, trabalhador formal/aposentado, baixa escolaridade. A escala apresentou alfa de Cronbach (α=0,849), com escore global (M=4,9), competência social (M=5.2±1,4), coesão familiar (M=5.1±1,3), percepção de si mesmo (M=5.0±1,0), recursos sociais (M=5.0±1,3), estilo estruturado (M=4.4±1,4) e futuro planejado (M=4.3±1,4). Conclusão: Evidenciado nível de resiliência elevado para as características competência social, coesão familiar, percepção de si mesmo e recursos sociais, pois apresentaram maior média, embora todos os fatores tenham apresentado média acima do ponto de corte da escala, sugerindo um nível de resiliência equânime em todos. No entanto, as características de resiliência não apresentaram relação com o tempo de amputação. (AU)

Objective: To identify the resistance characteristics of people with Diabetes Mellitus submitted to amputation surgery, and the relationship between the identified characteristics and the time of amputation. Methods: Descriptive, cross-sectional study with a quantitative approach, carried out in an emergency hospital, involving 80 people. A sociodemographic questionnaire was used to characterize the Resilience Scale for Adults. No relationship studies were applied or the Spearman Correlation Test. Results: Male predominance, Middle age (58 ± 10.4), married, mixed race, formal / residential worker, high school. On Cronbach's alpha scale (α = 0.849), with global score (M = 4.9), social competence (M = 5.2 ± 1.4), family relationship (M = 5.1 ± 1.3), perception of being equal (M = 5.0 ± 1.0), social resources (M = 5.0 ± 1.3), structured style (M = 4.4 ± 1.4) and planned future (M = 4 , 3 ± 1.4). Conclusion: Evidence of a high level of resilience for the characteristics of social competence, family cooperation, perception of the same social resources, presented by the highest media, incorporates all the parents presented by the cut-off point of the scale, suggesting a level of equity. resilience. in all. However, the characteristics of resilience will not be related to the time of the amputation. (AU)

Objetivo: Identificar las características de resistencia de las personas con Diabetes Mellitus sometidas a cirugía de amputación, y la relación entre las características identificadas y el momento de la amputación. Métodos: Estudio descriptivo, transversal con enfoque cuantitativo, realizado en un hospital de urgencias, con 80 personas. Se utilizó un cuestionario sociodemográfico para caracterizar la Escala de Resiliencia para Adultos. No se aplicaron estudios de relación ni la prueba de correlación de Spearman. Resultados: Predominio masculino, edad media (58 ± 10.4), casado, mestizo, trabajador formal / residencial, bachillerato. En la escala alfa de Cronbach (α = 0.849), con puntaje global (M = 4.9), competencia social (M = 5.2 ± 1.4), relación familiar (M = 5.1 ± 1.3), percepción de ser igual (M = 5.0 ± 1.0), recursos sociales (M = 5.0 ± 1.3), estilo estructurado (M = 4.4 ± 1.4) y futuro planificado (M = 4 , 3 ± 1.4). Conclusión: La evidencia de un alto nivel de resiliencia para las características de competencia social, cooperación familiar, percepción de los mismos recursos sociales, presentada por los medios de comunicación más altos, incorpora a todos los padres presentados por el punto de corte de la escala, lo que sugiere un nivel de equidad. resiliencia en todos. Sin embargo, las características de la resiliencia no estarán relacionadas con el momento de la amputación. (AU)

Síntomas depresivos en gestantes y violencia de pareja: un estudio transversal / Sintomas depressivos em gestantes e violência por parceiro íntimo: um estudo transversal / Depressive symptoms in pregnant women and intimate partner violence: a cross-sectional study

OBJETIVO: Evaluar la presencia de síntomas depresivos en gestantes y su asociación con la violencia de pareja. MÉTODOS: Este es un estudio piloto transversal de una muestra de 65 gestantes que recibieron atención prenatal en la Unidad Básica de Salud de la Universidad Federal de Amapá entre septiembre y octubre de 2018. Para la recolección de datos se utilizó un cuestionario socioeconómico, demográfico y obstétrico; la Escala de Depresión Posparto de Edimburgo, y el Estudio Multipaís sobre la salud de la mujer y la violencia doméstica. RESULTADOS: El 41,5% de las gestantes tienen síntomas depresivos, en el análisis de regresión logística, estos síntomas tienen una asociación significativa con mujeres que sufren algún tipo de violencia de pareja (OR = 6,74; IC 95% 2,0 - 21,7; p = 0,001) Además, estar empleada, ser soltera, tener bajo nivel de escolaridad, bajos ingresos familiares y embarazo no deseado influyeron significativamente en los síntomas depresivos durante el embarazo. CONCLUSIONES: Hubo un alto porcentaje de síntomas depresivos durante el embarazo y estos se relacionan con la violencia de pareja

OBJETIVO: Avaliar a presença de sintomas depressivos em gestantes e sua associação com a violência sofrida pelo parceiro. MÉTODOS: Trata-se de um estudo piloto transversal a partir de uma amostra de 65 gestantes que realizaram acompanhamento de pré-natal na Unidade Básica de Saúde da Universidade Federal do Amapá nos meses de setembro e outubro de 2018. Para coleta foi usado um questionário socioeconômico, demográfico e obstétrico; a Escala de Depressão Pós-Parto de Edimburgo; e o Estudo Multi-Países sobre Saúde da Mulher e Violência Doméstica. RESULTADOS: 41,5% das gestantes apresentaram sintomas depressivos, na análise de regressão logística esses sintomas mostraram ter associação significativa em mulheres que sofreram algum tipo de violência pelo parceiro íntimo (OR = 6,74; IC95% 2,0 - 21,7; p = 0,001), além disso, estar empregada, ser solteira, ter baixa escolaridade, baixa renda familiar e gravidez indesejada foram significativamente influenciadores para os sintomas depressivos durante a gestação. CONCLUSÕES: Houve alta porcentagem de sintomas depressivos durante a gestação e esses estiveram relacionados com a violência por parceiro íntimo

OBJECTIVE: To evaluate the presence of depressive symptoms in pregnant women and their association with intimate partner violence. METHODS: This is a cross-sectional pilot study conducted with a sample of 65 pregnant women who performed prenatal care at the Basic Health Unit of the Federal University of Amapá in September and October 2018. For data collection, a socioeconomic, demographic and obstetric questionnaire was used, apart from the Edinburgh Postpartum Depression Scale, and the Multi-Country Study on Women's Health and Domestic Violence. RESULTS: 41.5% of the pregnant women had depressive symptoms; in the logistic regression analysis, these symptoms have a significant association in women who suffer some type of intimate partner violence (OR = 6.74; 95% CI: 2.0 - 21.7; p = 0.001). In addition, being employed, being single, having low schooling, low family income, and unwanted pregnancies were affected by depressive symptoms during pregnancy. CONCLUSIONS: There was a high percentage of depressive symptoms during pregnancy and these were related to intimate partner violence

Functional capacity and life expectancy in elderly quilombolas.

OBJECTIVE: To evaluate the relationship between functional capacity and life expectancy of quilombola elders. METHOD: A quantitative, descriptive, cross-sectional study involving fifty-nine older adults from the quilombola community of Curiaú, Macapá-Amapá. A sociodemographic form was used to characterize the sample, and Lawton's and Herth's Hope Scales were used to measuring functional capacity and life expectancy, respectively. In the relationship study, the Spearman correlation test was applied. RESULTS: Elderly males aged 60-69 years (52.5%) and married (35.6%) prevailed. Functional capacity had a mean score of 22.4 (± 4.6) and a life expectancy of 41.5 (± 5.1), the correlation between the scale scores was positive and significant (R = 0.475; p <0.001). CONCLUSION: From the results concluded, when related levels of independence and life expectancy among themselves were significantly associated with being functionally independent elderly and having a better life expectancy.

Hipernefroma bilateral. Presentación de un caso / Bilateral Hypernephroma. A Case Report

El hipernefroma es un tumor renal común, más frecuente en hombres. Cuando es bilateral y hereditario tiene una conducta y manejo diferentes. En este caso se presenta una paciente femenina de 24 años diagnosticada hace un año con hipernefroma bilateral, mediante tomografía computarizada (TC) e imagen por resonancia magnética (RM), con componente hereditario y metástasis. Considerando los antecedentes familiares y con los resultados de los estudios radiológicos se realizó tratamiento sin complicaciones. La paciente se encuentra en seguimiento.

Hypernephroma is a common kidney cancer that has a higher frequency in men. When it is bilateral and hereditary it has a different behavior and treatment. In this case we present a 24 year old female patients who was diagnosed with bilateral hypernephroma one year ago, by means of computed tomography (CT) and magnetic resonance imaging (MRI) with hereditary components and metastasis. Considering the family's background and the use of radiological studies, the diagnosis and treatment was performed without complications. The patient is being followed up.

Validação de conteúdo e aparência de manual educativo para promoção da saúde mental infantil / Validation of content and appearance of an educational manual to promote children's mental health

RESUMO Objetivo validar o conteúdo e a aparência de um manual educativo para promoção da saúde mental infantil. Métodos trata-se de estudo metodológico, do qual participaram 16 especialistas (profissionais da saúde e educação) e seis do público-alvo (enfermeiros). O Índice de Validade de Conteúdo e o Índice de Concordância foram calculados conforme resposta ao instrumento, que avaliava objetivos, aparência, estrutura, organização, relevância e didática do manual. Resultados o Índice de Validade de Conteúdo foi de 0,984 para o público-alvo, e o Índice de Concordância foi de 100,0%. As principais modificações foram no título, nos objetivos e no referencial teórico, com exclusão de oficinas e revisão ortográfica e gramatical. Conclusão o manual apresentou Índices de Validade de Conteúdo e de Concordância satisfatórios. Ele pode auxiliar o enfermeiro e demais profissionais da saúde na promoção da saúde mental de crianças, difundindo o desenvolvimento da inteligência emocional.

ABSTRACT Objective to validate the content and appearance of an educational manual to promote children's mental health. Methods this is a methodological study, in which 16 specialists (health and education professionals) and six of the target audience (nurses) participated. The Content Validity Index and the Agreement Index were calculated according to the response to the instrument, which assessed the objectives, appearance, structure, organization, relevance and didactics of the manual. Results the Content Validity Index was 0.984 for the target audience, and the Agreement Index was 100.0%. The main changes were in the title, objectives and theoretical framework, excluding workshops and spelling and grammatical revision. Conclusion the manual presented satisfactory Content Validity and Agreement indexes. It can assist nurses and other health professionals in promoting children's mental health, promoting the development of emotional intelligence.

Functional capacity and life expectancy in elderly quilombolas / Capacidad funcional y esperanza de vida en negros cimarrones ancianos / Capacidade funcional e esperança de vida em idosos quilombolas

ABSTRACT Objective: To evaluate the relationship between functional capacity and life expectancy of quilombola elders. Method: A quantitative, descriptive, cross-sectional study involving fifty-nine older adults from the quilombola community of Curiaú, Macapá-Amapá. A sociodemographic form was used to characterize the sample, and Lawton's and Herth's Hope Scales were used to measuring functional capacity and life expectancy, respectively. In the relationship study, the Spearman correlation test was applied. Results: Elderly males aged 60-69 years (52.5%) and married (35.6%) prevailed. Functional capacity had a mean score of 22.4 (± 4.6) and a life expectancy of 41.5 (± 5.1), the correlation between the scale scores was positive and significant (R = 0.475; p <0.001). Conclusion: From the results concluded, when related levels of independence and life expectancy among themselves were significantly associated with being functionally independent elderly and having a better life expectancy.

RESUMEN Objetivo: Evaluar la relación entre la capacidad funcional y la esperanza de vida de negros cimarrones ancianos. Método: Estudio cuantitativo, descriptivo, transversal, envolviendo 59 ancianos de la comunidad de cimarrones de Curiaú, Macapá (Amapá). Han sido utilizados formulario sociodemográfico para caracterización de la muestra bien como la Escala de Lawton y la Escala de Esperanza de Herth, para medición de la capacidad funcional y esperanza de vida, respectivamente. En el estudio de relación, ha sido aplicado el Test de Correlación Spearman. Resultados: Prevalecieron ancianos del sexo masculino, entre 60 y 69 años (52,5%) y casados (35,6%). La capacidad funcional tuvo escore medio total de 22,4 (±4,6); y la esperanza de vida, de 41,5 (±5,1); la correlação entre los escores de las escalas han sido positiva y significativa (R = 0,475; p < 0,001). Conclusión: A partir de los resultados, cuando relacionados niveles de independencia y esperanza de vida entre sí, hubo asociación significativa entre ser anciano funcionalmente independiente y tener mejor esperanza de vida.

RESUMO Objetivo: Avaliar a relação entre a capacidade funcional e a esperança de vida de idosos quilombolas. Método: Estudo quantitativo, descritivo, transversal, envolvendo 59 idosos da comunidade quilombola do Curiaú, Macapá (Amapá). Foram utilizados formulário sociodemográfico para caracterização da amostra bem como a Escala de Lawton e a Escala de Esperança de Herth, para mensuração da capacidade funcional e esperança de vida, respectivamente. No estudo de relação, foi aplicado o Teste de Correlação de Spearman. Resultados: Prevaleceram idosos do sexo masculino, entre 60 e 69 anos (52,5%) e casados (35,6%). A capacidade funcional teve escore médio total de 22,4 (±4,6); e a esperança de vida, de 41,5 (±5,1); a correlação entre os escores das escalas foi positiva e significativa (R = 0,475; p < 0,001). Conclusão: A partir dos resultados, quando relacionados níveis de independência e esperança de vida entre si, houve associação significativa entre ser idoso funcionalmente independente e ter melhor esperança de vida.