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1.
BMJ Case Rep ; 13(11)2020 Nov 04.
Article in English | MEDLINE | ID: mdl-33148598

ABSTRACT

Amiodarone is an antiarrhythmic medication with many side effects. Neuromyopathy is a rare adverse effect. We present an 87-year-old woman with bilateral leg pain and weakness in the context of amiodarone. She was admitted to the Acute Geriatric Unit in Calgary, Alberta, Canada. On examination, hip flexor and extensor strength were 2/5 bilaterally while knee flexor and extensor strength were 4/5 and 3/5, respectively. Creatine kinase and C-reactive protein levels were normal. MRI of the lumbar spine showed mild central canal stenosis. Electromyography and nerve conduction testing showed a severe axonal length-dependent polyneuropathy of the left lower extremity. There was evidence of myopathic changes to the left iliopsoas muscle. Overall, a neuromyopathic process affecting the lower extremities was supported. After discontinuation of amiodarone, mobility and function significantly improved. Although a rare complication of amiodarone, neuromyopathy should be considered in patients with compatible symptomatology.


Subject(s)
Amiodarone/adverse effects , Muscle, Skeletal/physiopathology , Neuromuscular Diseases/chemically induced , Aged, 80 and over , Anti-Arrhythmia Agents/adverse effects , Atrial Fibrillation/drug therapy , Electromyography , Female , Humans , Lower Extremity , Muscle, Skeletal/drug effects , Neuromuscular Diseases/diagnosis , Neuromuscular Diseases/physiopathology , Tomography, X-Ray Computed
2.
J R Army Med Corps ; 161 Suppl 1: i52-i55, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26621811

ABSTRACT

INTRODUCTION: Considerable evidence has discussed the significant workload and advances in clinical care by UK Defence Medical Services (DMS) during recent conflicts in Iraq and Afghanistan. Although the DMS is not doctrinally staffed to deal with children on operations, severely ill and injured paediatric casualties continue to present to military medical facilities; therefore, staff must be competent to deliver the appropriate level of care. This paper reports the paediatric presentations to the emergency department (ED), at the Role 3 Medical Treatment Facility (MTF) in Camp Bastion, Afghanistan, over a 21-month period. The aim was to provide quantitative, statistical data of paediatric presentations seen by deployed ED nurses, to identify whether the current training was appropriate and to make recommendations for further training requirements for DMS ED nurses. METHOD: All paediatric presentations to the MTF ED between January 2011 and September 2012 were analysed. The following aspects of the admission were analysed: date of admission, mechanism of injury, injury sustained, discharge, length of stay in the ED and length of stay in the R3. RESULTS: There were 159 paediatric presentations to the ED in 2011 of which 56% warranted admission to the intensive treatment unit (ITU). In contrast, over the shorter period in 2012, 79% of 73 paediatric presentations were admitted to the ITU. The most common mechanism of injury was hostile action. 13% of the patients who presented to the ED in 2011 did not survive to discharge, compared with 11% the following year. CONCLUSION: Although the exposure to paediatric polytrauma during the conflicts in Afghanistan and Iraq is not replicated in peace time roles, it is likely that wherever emergency nurses are deployed the treatment of children will continue. Analysis of the service evaluation has led to the recommendations for specific skills that emergency nurses could develop during the pre-deployment phase to better prepare for caring for such patients. These include recognition of the sick child/triage, paediatric drug calculations, awareness of the massive transfusion requirements for children and skills to gain intravenous/intraosseous access in a child.


Subject(s)
Emergency Nursing , Emergency Service, Hospital , Military Nursing , Pediatrics , Wounds and Injuries/epidemiology , Wounds and Injuries/therapy , Afghan Campaign 2001- , Afghanistan , Humans , United Kingdom , Wounds and Injuries/pathology
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