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1.
Psychol Violence ; 9(3): 278-287, 2019 May.
Article in English | MEDLINE | ID: mdl-31086693

ABSTRACT

OBJECTIVE: Intimate partner violence (IPV) victimization and reproductive coercion place young women at risk for poor health. However, very few studies have examined the associations between IPV victimization and reproductive coercion among young couples nor investigated these associations longitudinally. METHOD: Data were collected during 2007-2011 from 296 pregnant adolescent and young couples enrolled in a prospective study. Couples were recruited at obstetrics and gynecology, and ultrasound clinics. RESULTS: Using the Actor-Partner Interdependence Model, results indicate significant actor and partner effects for IPV victimization and reproductive coercion victimization. Actor's prebirth IPV victimization, and actor's and partner's reproductive coercion victimization in a past relationship related to reproductive coercion victimization in the current pregnancy. Partner's reproductive coercion victimization in the current pregnancy related to psychological IPV victimization at the six-month follow-up, but this relationship dissipated at the twelve-month follow-up. CONCLUSIONS: A complex, co-occurring relationship exists between IPV victimization and reproductive coercion among young pregnant and parenting couples. Young couples transitioning from pregnancy to parenthood who experience reproductive coercion may be at risk for IPV. Pregnancy and parenting programs targeting young couples should be sensitive to the relationship between IPV and reproductive coercion victimization.

2.
J Health Psychol ; 24(7): 898-908, 2019 06.
Article in English | MEDLINE | ID: mdl-28810400

ABSTRACT

This study examines the effect of condom negotiation strategies on condom use and partner type and substance use before sex as moderators of strategy effectiveness. Women reported their daily sexual behavior during the last month. Withholding sex was more strongly associated with condom use when utilized with a non-casual sex partner. Directly requesting condom use was more strongly and using deceptive reasons to influence condom use was less strongly related to condom use during substance use. Results underscore the importance of understanding the contexts in which condom negotiation strategies are successful in order to improve HIV/sexually transmitted infection prevention efforts among women.


Subject(s)
Condoms , Negotiating/methods , Safe Sex/psychology , Sexual Partners/psychology , Sexually Transmitted Diseases/prevention & control , Substance-Related Disorders/psychology , Adolescent , Adult , Female , Humans , Male , Negotiating/psychology , Sexually Transmitted Diseases/psychology , Young Adult
3.
Child Maltreat ; 24(1): 26-35, 2019 02.
Article in English | MEDLINE | ID: mdl-30124064

ABSTRACT

Women who experience intimate partner violence (IPV) report high rates of HIV/sexual risk behaviors. Childhood abuse has been linked to HIV/sexual risk behaviors among IPV-victimized women; however, limited research has examined factors that may influence this association. The current study tested the moderating role of avoidant coping in the relation between childhood abuse types (physical, emotional, and sexual) and HIV/sexual risk behaviors. Participants were 212 community women currently experiencing IPV (mean age = 36.63 years, 67.0% African American). Higher levels of avoidant coping were related to more severe childhood abuse types. Severity of childhood abuse types was associated with greater HIV/sexual risk behaviors. Avoidant coping moderated the relation between childhood sexual abuse severity and HIV/sexual risk behaviors, such that this association was significant for IPV-victimized women with high (but not low) levels of avoidant coping. Findings suggest the utility of targeting avoidant coping in interventions aimed at preventing or reducing HIV/sexual risk behaviors among IPV-victimized women with a history of childhood sexual abuse.


Subject(s)
Adaptation, Psychological , Avoidance Learning , Child Abuse/psychology , HIV Infections/psychology , Intimate Partner Violence/psychology , Sexual Behavior/psychology , Adult , Child , Female , Humans , Risk-Taking
4.
J Trauma Stress ; 31(5): 775-780, 2018 10.
Article in English | MEDLINE | ID: mdl-30338577

ABSTRACT

Emotion regulation difficulties have been theoretically and empirically linked to posttraumatic stress disorder (PTSD). Previous research, however, has focused almost exclusively on difficulties regulating negative emotions. In this study, we explored the nature of difficulties regulating positive emotions in PTSD. Participants were women who had experienced domestic violence (N = 210; 48.6% African American; Mage = 36.14 years). Higher levels of nonacceptance of positive emotions, difficulties engaging in goal-directed behaviors when experiencing positive emotions, and difficulties controlling impulsive behaviors when experiencing positive emotions were related to a higher level of PTSD symptom severity overall and for the intrusion, avoidance/emotional numbing, and hyperarousal clusters, rs = .24-.37. The presence (vs. absence) of a probable PTSD diagnosis was related to greater difficulties engaging in goal-directed behaviors, d = 0.54, and controlling impulsive behaviors, d = 0.34, when experiencing positive emotions. Results suggest the potential utility of assessing and treating difficulties regulating positive emotions among domestic violence-victimized women with PTSD.


Subject(s)
Crime Victims/psychology , Domestic Violence/psychology , Expressed Emotion , Stress Disorders, Post-Traumatic/psychology , Adult , Affective Symptoms/complications , Aged , Cross-Sectional Studies , Female , Humans , Middle Aged , Self Report , Stress Disorders, Post-Traumatic/complications , Young Adult
5.
Women Health ; 58(5): 483-497, 2018.
Article in English | MEDLINE | ID: mdl-28402194

ABSTRACT

Physical and psychological intimate partner violence (IPV) are prevalent on college campuses and may affect young women's condom use behavior. This study explored condom negotiation as a mediator of the relation of physical and psychological IPV to condom use among college women. A total of 235 heterosexual college women were recruited during September 2012-May 2013. Participants completed online questionnaires assessing lifetime history of IPV, frequency of condom negotiation, and use of condoms during the last 30 days. Specific forms of psychological IPV were related to less condom use. This association was mediated by condom negotiation, such that those who had experienced psychological IPV were less likely to negotiate condom use, and as a result, less likely to report using condoms in the past 30 days. Campus-based sexual health efforts should consider the relation of psychological IPV to condom negotiation and condom use and offer skills to promote condom negotiation among college women to increase condom use and reduce their risk of sexually transmitted infections.


Subject(s)
Coercion , Communication , Condoms/statistics & numerical data , Intimate Partner Violence/psychology , Negotiating , Sexual Partners/psychology , Adolescent , Adult , Fear , Female , Humans , Safe Sex , Sexual Behavior/psychology , Sexually Transmitted Diseases/prevention & control , Urban Population , Young Adult
6.
BMC Womens Health ; 17(1): 85, 2017 Sep 18.
Article in English | MEDLINE | ID: mdl-28923034

ABSTRACT

BACKGROUND: HIV persists as a public health emergency in South Africa, especially among women of childbearing age. In response to the HIV epidemic, the Joint United Nations Programme on HIV/AIDS has put forth the 90-90-90 global goals to achieve an AIDS-free generation by 2020. This goal aspires to have 90% of people living with HIV diagnosed; 90% of those who test positive on sustained antiretroviral therapy (ART); and 90% of those on ART be virally suppressed. Ensuring access to ART is an important first step in reducing HIV incidence, especially among vulnerable populations such as women who use substances and bear the burden of HIV in South Africa. Additionally, alcohol and other drug (AOD) use and exposure to gender-based violence are associated with increased risk of HIV infection and reduced adherence to ART. However, no research has estimated ART adherence rates for women who use substances in South Africa since the government approved the provision of ART to all people living with HIV. METHODS: The Women's Health CoOp (WHC) is an evidence-based, woman-focused, behavioral intervention that addresses the intersecting risks of AODs, sex behaviors, and violence and victimization, with the primary goal of increasing skills and knowledge to reduce substance abuse and HIV risks and to improve ART adherence. The WHC has been packaged for further dissemination. This article describes the study protocol used to assess the feasibility and acceptability of implementing the WHC intervention into standard of care in Cape Town health clinics and substance abuse rehabilitation centers to reduce HIV risk behavior and increase ART adherence among women who use substances and are living with HIV. DISCUSSION: Because few of the interventions that demonstrate efficacy for HIV prevention and ART adherence in randomized trials are sustainable, studies to adapt and test intervention variations are needed to determine the best strategies for implementing them in real-world, high-risk settings. However, implementation in real-world settings presents challenges. Consequently, intervention developers should consider the strengths and limitations of their anticipated implementation setting by engaging with key stakeholders before, during, and after the adaptation and implementation process when developing and attempting to scale-up interventions. TRIAL REGISTRATION: NCT 02733003 and date approved 1/21/2016.


Subject(s)
Anti-HIV Agents/therapeutic use , HIV Infections/drug therapy , HIV Infections/prevention & control , Substance-Related Disorders/prevention & control , Vulnerable Populations/psychology , Vulnerable Populations/statistics & numerical data , Women's Health , Adult , Female , HIV Infections/epidemiology , Humans , Male , Middle Aged , South Africa/epidemiology , Young Adult
7.
AIDS Behav ; 21(Suppl 2): 155-166, 2017 Nov.
Article in English | MEDLINE | ID: mdl-28887751

ABSTRACT

This cross-sectional study presents baseline data from women (n = 641) in a community-based randomized trial in Pretoria, South Africa. Women were eligible if they reported recent alcohol or other drug (AOD) use and condomless sex. Latent class analyses were conducted separately for those who reported sex work and those who did not. Among those who reported sex work, a Risky Sex class (n = 72, 28%) and Low Sexual Risk class (n = 190, 73%) emerged. Those in the Risky Sex class were more likely to report that their last episode of sexual intercourse was with their boyfriend (vs. a client/other partner) compared with the Low Sexual Risk class (p < 0.001). Among participants who did not report sex work, a Drug-Using, Violence-Exposed, and Impaired Sex class (n = 53; 14%) and Risky Sex and Moderate Drinking class (n = 326; 86%) emerged. The findings suggest that interventions for women who engage in sex work should promote safer sexual behavior and empowerment with main partners. Women who use AODs, experience physical or sexual violence, and have impaired sex may be a key population at risk for HIV and should be considered for tailored behavioral interventions in conjunction with South Africa's plan to disseminate HIV prevention methods to vulnerable women. TRIAL REGISTRATION: ClinicalTrials.gov registration NCT01497405.


Subject(s)
Black People/psychology , HIV Infections/prevention & control , Sex Work , Sexual Behavior/ethnology , Substance-Related Disorders/ethnology , Vulnerable Populations/ethnology , Adult , Alcohol Drinking/adverse effects , Black People/statistics & numerical data , Cross-Sectional Studies , Female , Humans , Risk Factors , Risk-Taking , Sex Offenses/statistics & numerical data , Sexual Behavior/statistics & numerical data , Sexual Partners , South Africa/epidemiology , Substance-Related Disorders/epidemiology , Substance-Related Disorders/psychology , Vulnerable Populations/psychology , Vulnerable Populations/statistics & numerical data
8.
J Early Adolesc ; 37(2): 267-283, 2017 Feb.
Article in English | MEDLINE | ID: mdl-28461714

ABSTRACT

This study examines the role of condom use knowledge and attitudes, and parent-teen communication about sex and relationship quality on reports of condom use self-efficacy among rural, African American youth. Participants were 465 North Carolinian youth (10-14 years). Results indicated that greater condom use self-efficacy was predicted by greater knowledge of condom use (ß = .206; p < .001), more favorable attitudes toward condom use (ß = -.20; p < .0001) and parent-teen communication about sex (ß = .13; p < .05), and actual parent-teen communication about sex and dating (ß = .14; p < .05). There was low agreement between parents and youth on measures related to parent-teen communication about sex. Findings call for interventions targeting improvement of condom use knowledge among early adolescents, as well as parent-teen communication about sex. In addition, given the low parent-teen agreement regarding sexual communication, parent-teen sexual communication is an important point of intervention.

9.
Anxiety Stress Coping ; 30(3): 347-363, 2017 May.
Article in English | MEDLINE | ID: mdl-27575609

ABSTRACT

BACKGROUND: Past research underscores the key role of coping strategies in the development, maintenance, and exacerbation of posttraumatic stress disorder (PTSD) symptoms. The goal of the current study was to extend existing literature by examining whether race/ethnicity moderates the relations among coping strategies (social support, problem-solving, avoidance) and PTSD symptom clusters (intrusion, avoidance, numbing, arousal). METHODS: Participants were 369 community women (134 African Americans, 131 Latinas, 104 Whites) who reported bidirectional aggression with a current male partner. Multigroup path analysis was utilized to test the moderating role of race/ethnicity in a model linking coping strategies to PTSD symptom clusters. RESULTS: The strength and direction of relations among coping strategies and PTSD symptom clusters varied as a function of race/ethnicity. Greater social support coping was related to more arousal symptoms for Latinas and Whites. Greater problem-solving coping was related to fewer arousal symptoms for Latinas. Greater avoidance coping was related to more symptoms across many of the PTSD clusters for African Americans, Latinas, and Whites, however, these relations were strongest for African Americans. CONCLUSION: Results provide support for the moderating role of race/ethnicity in the relations among coping strategies and PTSD symptom clusters, and highlight potential targets for culturally informed PTSD treatments.


Subject(s)
Adaptation, Psychological , Ethnicity/psychology , Racial Groups/psychology , Spouse Abuse/psychology , Stress Disorders, Post-Traumatic/psychology , Women/psychology , Adolescent , Adult , Black or African American/psychology , Black or African American/statistics & numerical data , Aged , Ethnicity/statistics & numerical data , Female , Hispanic or Latino/psychology , Hispanic or Latino/statistics & numerical data , Humans , Middle Aged , Racial Groups/statistics & numerical data , Spouse Abuse/statistics & numerical data , Stress Disorders, Post-Traumatic/epidemiology , United States/epidemiology , White People/psychology , White People/statistics & numerical data , Young Adult
10.
AIDS Behav ; 21(8): 2233-2242, 2017 Aug.
Article in English | MEDLINE | ID: mdl-27778220

ABSTRACT

Women who experience intimate partner violence (IPV) report higher rates of HIV-risk behaviors. However, few studies have examined factors that may influence the strength of the link between IPV and HIV-risk behaviors. The goal of the current study was to extend extant research by evaluating the potential moderating role of avoidant coping in this relation. Participants were 212 women currently experiencing IPV (M age = 36.63, 70.8 % African American) who were recruited from the community. Significant positive associations were found between physical, psychological, and sexual IPV severity and both avoidant coping and HIV-risk behaviors. Avoidant coping moderated the relations between both physical and psychological IPV severity and HIV-risk behaviors, such that physical and psychological IPV severity were significantly associated with HIV-risk behaviors when avoidant coping was high (but not low). Findings underscore avoidant coping as an important factor in identifying and subsequently treating IPV-victimized women vulnerable to HIV-risk behaviors.


Subject(s)
Adaptation, Psychological , Avoidance Learning , Battered Women/psychology , Health Risk Behaviors , Intimate Partner Violence/psychology , Sexual Behavior/psychology , Spouse Abuse/psychology , Adolescent , Adult , Crime Victims , Female , HIV Infections , Humans , Middle Aged , Risk-Taking , Sexual Partners , Young Adult
11.
AIDS Care ; 29(4): 516-523, 2017 04.
Article in English | MEDLINE | ID: mdl-27590004

ABSTRACT

BACKGROUND: HIV and sexually transmitted infections (STIs) disproportionately affect women who experience intimate partner violence (IPV). OBJECTIVE: The current study (1) applied a syndemic framework to study the collective effects of problematic drug use, hazardous drinking, depression, and posttraumatic stress disorder (PTSD) on fear of condom negotiation, condom negotiation, and condom use and (2) evaluated condom negotiation (controlling for fear of condom negotiation) as a mediator of the association between syndemic severity and condom use among low-income IPV-exposed women. METHODS: Participants were 158 women living in the community and experiencing ongoing IPV who completed face-to-face, computer-assisted interviews. RESULTS: Almost three-fourths of the participants reported problematic drug use, hazardous drinking, depression, and/or PTSD; many of these factors were correlated, indicating a syndemic. Multivariate logistic and linear regression analyses revealed associations between syndemic severity and fear of condom negotiation (OR = 1.57, p = .02), condom negotiation (ß = -8.51, p = .001), and condom use (ß = -8.26, p = .01). Meditation analyses identified condom negotiation as a mediator of the association between syndemic severity and condom use (effect = -6.57, SE = 2.01, [95% CI: -10.66, -2.77]). CONCLUSIONS: Results fill a critical gap in previous research by identifying condom negotiation as a mechanism through which this syndemic affects condom use. Prevention and intervention programs should consider addressing condom negotiation to reduce sexual risk among this high-risk population. Further, because IPV-exposed women may experience fear related to condom negotiation, it is critical that prevention and intervention efforts for this population offer skills to safely negotiate condom use, increase condom use, and reduce STI and HIV risk.


Subject(s)
Condoms/statistics & numerical data , Negotiating/psychology , Spouse Abuse/psychology , Substance-Related Disorders/epidemiology , Adult , Alcohol-Related Disorders/epidemiology , Depression/epidemiology , Fear , Female , HIV Infections/epidemiology , Humans , Middle Aged , Poverty , Safe Sex , Severity of Illness Index , Stress Disorders, Post-Traumatic/epidemiology
12.
Psychol Trauma ; 9(3): 370-378, 2017 05.
Article in English | MEDLINE | ID: mdl-27736140

ABSTRACT

OBJECTIVE: Intimate partner violence (IPV) is associated with heightened psychopathology symptoms and risky behaviors. However, extant investigations are limited by their focus on IPV victimization, despite evidence to suggest that victimization and aggression frequently co-occur. Further, research on these correlates often has not accounted for the heterogeneity of women who experience victimization. METHOD: The present study utilized latent profile analysis to identify patterns of physical, psychological, and sexual victimization and aggression in a convenience sample of 212 community women experiencing victimization (Mage = 36.63, 70.8% African American), as well as examined differences in psychopathology symptoms (i.e., posttraumatic stress symptoms [PTSS] and depressive symptoms) and risky behaviors (i.e., drug problems, alcohol problems, deliberate self-harm (DSH), HIV-risk behaviors) across these classes. RESULTS: Four classes of women differentiated by severities of victimization and aggression were identified. Greater psychopathology symptoms were found among classes defined by greater victimization and aggression, regardless of IPV type. Risky behaviors were more prevalent among classes defined by greater sexual victimization and aggression in particular. CONCLUSIONS: Findings highlight the importance of developing interventions that target the particular needs of subgroups of women who experience victimization. (PsycINFO Database Record


Subject(s)
Crime Victims/psychology , Depression/diagnosis , Intimate Partner Violence/psychology , Risk-Taking , Self-Injurious Behavior/psychology , Stress Disorders, Post-Traumatic/diagnosis , Adolescent , Adult , Aggression/psychology , Depression/psychology , Female , Humans , Middle Aged , Stress Disorders, Post-Traumatic/psychology , Stress, Psychological/diagnosis , Stress, Psychological/psychology , Unsafe Sex/psychology , Young Adult
13.
AIDS Behav ; 20(8): 1609-20, 2016 08.
Article in English | MEDLINE | ID: mdl-26837633

ABSTRACT

There is a critical need to examine protective and risk factors of anxiety and depressive symptoms among people living with HIV in order to improve quality of life. Structural equation modeling was used to examine the associations between HIV-related shame, sexual abuse-related shame, posttraumatic growth, and anxiety and depressive symptoms among a cohort of 225 heterosexual women and men who have sex with men (MSM) living with HIV who have experienced childhood sexual abuse (CSA). Higher sexual abuse-related shame was related to more anxiety and depressive symptoms for heterosexual women. Higher posttraumatic growth predicted less anxiety symptoms for only heterosexual women. Higher posttraumatic growth predicted less depressive symptoms for heterosexual women and MSM, but the magnitude of this effect was stronger for heterosexual women than MSM. Psychosocial interventions may need to be tailored to meet the specific needs of heterosexual women and MSM living with HIV and CSA.


Subject(s)
Anxiety/diagnosis , Child Abuse, Sexual/psychology , Depression/diagnosis , HIV Infections/psychology , Heterosexuality/psychology , Homosexuality, Male/psychology , Quality of Life/psychology , Shame , Adaptation, Psychological , Adult , Anxiety/psychology , Child , Depression/psychology , Female , Humans , Male , Risk Factors , Social Support
14.
J Pediatr Oncol Nurs ; 33(3): 199-208, 2016.
Article in English | MEDLINE | ID: mdl-26668213

ABSTRACT

Human papillomavirus (HPV) vaccination is recommended for all female survivors of childhood cancer; yet, it is underused. Parent-child sexual communication and health care provider recommendation for HPV vaccination influence familial vaccination decisions. However, caregivers may be less likely to discuss sexual health issues with survivors as compared to healthy peers. Therefore, this study compared mothers of daughters with/without history of childhood cancer on measures of sexual communication, HPV-specific communication, and health care provider recommendation for HPV vaccination, and examined the effects of sociodemographic and medical factors on these measures. There were no differences between mothers of survivors/noncancer survivors on the outcomes (Ps > .05). Among all mothers, daughter's age was associated with sexual communication (Ps < .05). Household income and daughter's age were associated with health care provider recommendation for vaccination (Ps < .05). Among mothers of survivors, daughter's age at diagnosis was associated with sexual communication, HPV-specific communication, and health care provider recommendation for vaccination (Ps < .05). Findings have implications for the role of health care providers as advocates for mother-daughter sexual communication and HPV vaccination, especially among survivors of childhood cancer.


Subject(s)
Caregivers/psychology , Nuclear Family/psychology , Papillomavirus Vaccines/therapeutic use , Parent-Child Relations , Survivors/psychology , Child , Female , Humans , Mothers , Uterine Cervical Neoplasms/prevention & control
15.
J Sex Res ; 52(4): 470-83, 2015.
Article in English | MEDLINE | ID: mdl-24670110

ABSTRACT

The aim of this review was to summarize factors associated with condom negotiation among heterosexual men. Literature searches were conducted using multiple databases spanning several disciplines. Studies examining psychological, demographic, relational, communication, and environmental factors related to condom negotiation are described, and a three-dimensional framework of condom negotiation is proposed. This framework of condom negotiation may aid researchers in operationalizing this construct, organizing this literature, and facilitating measurement development. We used this three-dimensional framework to articulate the influence of gender, ethnicity, relationship type, partner characteristics, trauma history, post-traumatic stress, and alcohol use on condom negotiation. Areas for future research are outlined. More research is needed to understand how these factors interact to influence condom negotiation, as well as the interaction between gender and the identified factors.


Subject(s)
Condoms/statistics & numerical data , Negotiating/psychology , Safe Sex , Adult , Humans , Male , Safe Sex/ethnology , Safe Sex/psychology , Safe Sex/statistics & numerical data
16.
Health Psychol ; 33(8): 868-77, 2014 Aug.
Article in English | MEDLINE | ID: mdl-24364376

ABSTRACT

OBJECTIVE: To identify correlates of risky sexual behavior among adolescents surviving childhood cancer. METHODS: The Child Health and Illness Profile-Adolescent Edition (CHIP-AE) was completed by 307 survivors of childhood cancer aged 15-20 years (M age at diagnosis 1.53 years; range 0-3.76). Univariate analyses were performed using χ² and Fisher's Exact tests, and multivariable logistic regression models were used to calculate odds ratios (OR) and 95% confidence intervals (CI) for risky sexual behaviors. RESULTS: Diagnosis of central nervous system cancer (OR = .13, 95% CI: .02-.96, p < .05), no history of beer or wine consumption (OR = .20, CI: .06-.68, p = .01), and fewer negative peer influences (OR = .28, CI: .09-.84, p = .02) associated with decreased likelihood of sexual intercourse. Good psychological health (scores ≥-1.5 SD on the CHIP-AE Emotional Discomfort scale) associated with decreased risk of early intercourse (OR = .19, CI: .05-.77, p = .02), whereas high parental education (≥ college degree) associated with decreased risk of multiple lifetime sexual partners (OR = .25, CI: .09-.72, p = .01). Increased time from diagnosis (OR = .27, CI: .10-.78, p = .02) and psychological health (OR = .09, CI: .02-.36, p < .01) associated with decreased risk of unprotected sex at last intercourse, whereas high parent education associated with increased risk (OR = 4.27, CI: 1.46-12.52, p = .01). CONCLUSIONS: Risky sexual behavior in adolescents surviving childhood cancer is associated with cancer type, time since diagnosis, psychological health, alcohol use, and peer influences. Consideration of these factors may provide direction for future interventions designed to reduce adolescent sexual risk-taking.


Subject(s)
Neoplasms/therapy , Risk-Taking , Sexual Behavior/psychology , Survivors/psychology , Adolescent , Cohort Studies , Female , Humans , Male , Risk Factors , Sexual Behavior/statistics & numerical data , Survivors/statistics & numerical data , Young Adult
17.
Stud Health Technol Inform ; 172: 33-42, 2012.
Article in English | MEDLINE | ID: mdl-22910499

ABSTRACT

Effective vaccination is now available to prevent human papillomavirus (HPV), the most common sexually transmitted infection and the cause of cervical cancer, the second most common cancer among women worldwide. HPV vaccine uptake is particularly important for females surviving cancer, who are at high risk for HPV-related complication due to the direct and indirect effects of cancer therapy. Thus, Version 3.0 of the Children's Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent and Young Adult Cancer recommends HPV vaccination for all eligible females surviving childhood cancer. Because this vaccine was only FDA approved in 2006, little is known about the complexity of vaccination uptake among those surviving childhood cancer. This chapter describes HPV vaccination and its usefulness in survivors of childhood cancer, provides a rationale for describing survivors as being at increased risk for HPV-related complication, identifies factors that are predictive of HPV vaccination, and discusses the utilization of these predictors in designing strategies to promote adherence to the HPV vaccination recommendations among survivors.


Subject(s)
Neoplasms , Papillomavirus Vaccines/administration & dosage , Primary Prevention , Survivors , Uterine Cervical Neoplasms/prevention & control , Adolescent , Adult , Alphapapillomavirus/immunology , Female , Humans , Immunization Programs/statistics & numerical data , Middle Aged , Risk Factors , Uterine Cervical Neoplasms/virology , Young Adult
18.
Pediatrics ; 129(3): e762-70, 2012 Mar.
Article in English | MEDLINE | ID: mdl-22311995

ABSTRACT

BACKGROUND: Children undergoing stem cell transplantation (SCT) are thought to be at risk for increased distress, adjustment difficulties, and impaired health-related quality of life (HRQL). We report results of a multisite trial designed to improve psychological adjustment and HRQL in children undergoing SCT. METHODS: A total of 171 patients and parents from 4 sites were randomized to receive a child-targeted intervention; a child and parent intervention; or standard care. The child intervention included massage and humor therapy; the parent intervention included massage and relaxation/imagery. Outcomes included symptoms of depression and posttraumatic stress, HRQL, and benefit finding. Assessments were conducted by patient and parent report at admission and SCT week+24. RESULTS: Across the sample, significant improvements were seen on all outcomes from admission to week+24. Surprisingly, patients who had SCT reported low levels of adjustment difficulties at admission, and improved to normative or better than average levels of adjustment and HRQL at week+24. Benefit finding was high at admission and increased at week+24; however, there were no statistically significant differences between intervention arms for any of the measures. CONCLUSIONS: Although the results do not support the benefits of these complementary interventions in pediatric SCT, this may be explained by the remarkably positive overall adjustment seen in this sample. Improvements in supportive care, and a tendency for patients to find benefit in the SCT experience, serve to promote positive outcomes in children undergoing this procedure, who appear particularly resilient to the challenge.


Subject(s)
Adaptation, Psychological , Complementary Therapies/methods , Hematologic Neoplasms/therapy , Quality of Life , Stem Cell Transplantation/psychology , Adolescent , Age Factors , Analysis of Variance , Cancer Care Facilities , Child , Combined Modality Therapy , Female , Follow-Up Studies , Hematologic Neoplasms/mortality , Hematologic Neoplasms/pathology , Humans , Informed Consent , Male , Postoperative Care/methods , Preoperative Care/methods , Reference Values , Risk Assessment , Severity of Illness Index , Sex Factors , Stem Cell Transplantation/methods , Survival Rate , Treatment Outcome
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