ABSTRACT
BACKGROUND: The increase in candidates for kidney transplant has led to growth in the number of living donor transplants. Therefore, studies that adequately evaluate the possible long-term consequences of elective transplant nephrectomy are needed. OBJECTIVE: To evaluate the possible long-term adverse effects of transplant nephrectomy on the renal function of living kidney donors. DESIGN: A cross-sectional study. PARTICIPANTS: Thirty-three living kidney donors registered in the transplant programme of a centre in Alagoas, Brazil. MEASUREMENTS: Demographic characteristics, anthropometric measures, clinical data and biomarkers (creatinine, eGFR, microalbuminuria, cholesterol and triglycerides) were measured. Creatinine clearance was calculated using the Cockcroft-Gault and Modification of Diet in Renal Disease formulae. RESULTS: Of the 33 individuals, 63.63% were female, and the median age was 45 years. Additionally, 24.24% of these individuals had altered blood pressure, 39.39% had altered abdominal circumference (AC) and 36.36% were obese, with a body mass index ≥30. Furthermore, 33.33% of these individuals had elevated triglyceride levels. The average eGFR was 97.33 (33.03-175.9) ml/min/1.73 m2 (CG) and 84.14 (29.4-131) ml/min/1.73 m2 (MDRD). The microalbuminuria level was altered in 12.12% patients. CONCLUSION: Kidney donation is unquestionably a safe procedure. However, a better understanding of the long-term consequences of living donor kidney transplantation is still needed. This knowledge may have important implications for the follow-up of these patients. Our study has demonstrated a non-negligible presence of an early marker of glomerular injury and a decrease in the GFR of some patients, thereby reinforcing the proposal for long-term follow-up of living kidney donors.
Subject(s)
Glomerular Filtration Rate , Kidney Transplantation/adverse effects , Kidney/physiology , Living Donors/statistics & numerical data , Adult , Aged , Albuminuria/urine , Blood Pressure , Body Mass Index , Brazil , Creatinine/analysis , Creatinine/blood , Cross-Sectional Studies , Female , Humans , Kidney Transplantation/methods , Long Term Adverse Effects , Male , Middle Aged , Nephrectomy/rehabilitation , Nephrectomy/standards , Tissue and Organ Harvesting/adverse effectsABSTRACT
O universo de representações do sujeito e sua forma de conceber a vida estão relacionados com a maneira de lidar com o adoecimento. Este estudo teve como objetivo identificar as crenças quanto ao tratamento e à cura, compreendendo o sistema de representações veiculadas e transmitidas culturalmente. A pesquisa foi realizada no Serviço de Nefrologia do Hospital do Açúcar, sendo entrevistados 25 sujeitos em hemodiálise. Constatou-se que, apesar da compreensão das informações transmitidas, a busca por tratamentos alternativos foi de 52 por cento da amostra. Dentre estes, apenas 8 por cento não tinham escolaridade. Diante de tais dados, a pesquisa buscou delinear uma relação entre adoecimento, tratamento, crenças e cultura. Observou-se que quando a pessoa se vê diante da doença, busca os recursos possíveis para manter sua vida, independentemente do nível intelectual e do esquema de transmissão de informações, o que reforça a influência das crenças nas condições de adoecimento e cura.(AU)
The way in which a patient expresses him or herself, and the way in which a patient understands life, have bearing on the way in which a patient copes with sickness. This study had as its purpose the identification of beliefs as much as treatment and cure, and the understanding of the way in which expression is culturally couched and transmitted. The study was carried out in the nephrology section of The Sugar Hospital (Hospital do Açucar). Twenty-five individuals on hemodialysis were interviewed. It was confirmed that, in spite of understanding the information transmitted, 52 percent of the sample sought alternative treatment. Of these, only 8 percent had no schooling. Faced with such data, the study sought to delineate a relationship between sickness, treatment, belief, and culture. It was observed that when the individual confronts the fact that he or she has become sick in some way, the individual searches out whatever resources to remain alive. This is so independent of ones intellectual level or of the way in which information was communicated to the patient. This reinforces the influence of belief in relation to sickness or cure.(AU)
