Total Shoulder Reverse Arthroplasty in Alkaptonuria: An Effective Option to Treat a Complication of a Rare Disease.

Introduction: Alkaptonuria (AKU) is a rare autosomal recessive disorder in which tyrosine metabolism is altered. There is a deficiency of the Homogentisate 1,2-dioxygenase enzyme (homogentisic acid oxidase) This enzyme is responsible for the metabolism of the tyrosine - homogentisic acid - in maleylacetoacetic acid. Accumulation of homogenous acid occurs in urine and conjunctival tissue in the second with important deleterious effects on cartilage and bone. The most limiting complication is progressive degenerative arthropathy, especially in the axial and load load-bearing joints, with a lower tendency to affect the shoulder. Because of its rarity little is known about the results of arthroplasties in these patients. Case Report: A 60 -years -old man, retired, with a history of right knee arthroplasty 6 years ago (performed in another hospital). Sent to the orthopedic consultation due to intense shoulder pain. The case was revealed to be a rare disease: arthropathy due AKU. He was treated with total shoulder reverse arthroplasty. Currently with two 2 years of follow-up, with excellent functional results. Conclusion: The most commonly performed procedure, in this patients, is the hip prosthesis and there are few reported cases of shoulder arthroplasty. However, the results of our follow follow-up are good and encouraging.

Dental evaluation specificity in orofacial damage assessment: A serial case study.

INTRODUCTION: The evaluation of medico-legal post-traumatic events has been increasing over the last decades. This study analysed the input of dental evaluation in orofacial damage assessment, highlighting the individual's biopsychosocial model, by a serial case study. It is aimed to analyse the physical as well as the psychological repercussions of traumatic events. It also aimed to relate the type of trauma impact with the individual's sequelae. MATERIAL AND METHOD: An observational and retrospective study was carried out of Portuguese medico-legal database. A serial case study was distinguished by the direction of the impact: frontal striking, lateral striking and clashing with a bidirectional (frontal-lateral). RESULTS AND DISCUSSION: 7 cases fulfilled the inclusion criteria, as a pilot study. They have in common the involvement of the 2 lower thirds of the face, including the temporomandibular joint. The consolidation of the maxillary bone fractures does not always correspond to restituto ad integrum. CONCLUSION: The impact direction may guide clinical examination in detecting permanent impairment, emphasizing temporomandibular joint disorders, as well as their association with psychosocial repercussions. The medical-dental examination is differentiating and relevant to the accomplishment of the general objective of damage assessment.

Tri-dimensional pattern analysis of foodstuff bitemarks - A pilot study of tomographic database.

The analysis of bitemarks has been mostly done through analogical methods. The advent of current technologies brings new and more reliable tools for analyzing evidence. Bitemarks can now be turned into more consistent evidence by using a digital tridimensional (3D) analysis. The aim of this study is to propose a reliable, accurate and monitorized approach of 3D bitemark analysis. 12 cranium Cone Beam Computed Tomographic (CBCT) files were randomly selected from a clinical database (Coimbra Hospital and University Center/Faculty of Medicine of the University of Coimbra). The individuals were recalled to bite an apple (golden delicious 65/80) immediately subjected to a CBCT scan. The 3D rendering of every bitemark was compared with the 3D upper dental arches obtained from the CBCT cranium scans of the simulated suspects. The research team was composed by 5 elements. The matching process consists of corresponding landmark points, in both the bitemark and the suspects' dentition (upper dental arch). 144 comparisons were obtained. The Kappa statistics analysis was performed. Cohen's Kappa values were obtained between 0,690 and 0,910. Fleiss Kappa obtained a value of 0,767. The Friedman's test was performed and the normality assumption was not verified (p>0,05). A non-destructive protocol of bitemark study by 3D analysis of tomographic volumes was presented. The statistic analysis supports its accuracy and reliability. This experimental study opens doors to a future where bitemark analysis could be done through software that searches for matching dentitions in a CBCT database.