ABSTRACT
98 children with simple obesity were investigated. The prevalence of cardiovascular diseases (hypertension, coronary heart disease including heart infarction, disturbances of the cerebral circulation) and diabetes in parents and relatives of the obese children have been evaluated. The relation between the type of obesity (androidal, gynoidal) and the prevalence of the above complications in the family history was assessed. No correlation between the type of obesity and the mentioned diseases was observed.
Subject(s)
Adipose Tissue/metabolism , Arteriosclerosis/etiology , Cardiovascular Diseases/genetics , Diabetes Mellitus, Type 1/etiology , Diabetes Mellitus/etiology , Diabetic Angiopathies/etiology , Obesity/complications , Adult , Arteriosclerosis/genetics , Cardiovascular Diseases/metabolism , Child , Diabetes Mellitus/genetics , Diabetic Angiopathies/genetics , Disease Susceptibility , Female , Humans , Male , Obesity/genetics , Risk FactorsABSTRACT
Distribution of the fat tissue has been estimated in 94 children with simple obesity and in 100 children with normal parameters of the somatic development. The relation of waist measurement (at the navel level) to the hip measurement (at the level of sacral bone) (p/b) was evaluated. This ratio was higher in the group of the obese than in the normotensive children. Higher values of the waist measurement can indicate an excessive fat tissue deposition in the epigastrium. This is a poor prognostic factor as it indicates the greater risk of complications of obesity. This children should be followed up.
Subject(s)
Adipose Tissue/pathology , Anthropometry , Obesity/pathology , Body Constitution , Hip , Humans , Obesity/complicationsABSTRACT
Plasma fatty acids contents and dynamics of the left cardiac ventricle contractions were determined in 48 children with simple obesity. Significant deterioration of the dynamics of left ventricle contractions was seen in obese children. It included prolongation of QSIIJ, QI, and PEPI and shortening of LVETI. Correlation of the total contraction time, pre-ejection period and contractility index with plasma saturated and unsaturated fatty acids levels has been demonstrated.
Subject(s)
Fatty Acids/blood , Myocardial Contraction/physiology , Obesity/physiopathology , Adolescent , Child , Child, Preschool , Electrocardiography , HumansABSTRACT
Percent composition of the plasma fatty acids in 48 children with simple obesity was determined with gas-chromatography. Thirty seven healthy, normotensive children served as the control group. An increased content of the saturated fatty acids and decreased content of the unsaturated fatty acids together with the decrease in unsaturated fatty acids:multi-unsaturated fatty acids ratio were seen in children with simple obesity.
Subject(s)
Fatty Acids/blood , Obesity/blood , Adolescent , Child , Child, Preschool , Fatty Acids, Unsaturated/blood , Humans , Myocardial ContractionSubject(s)
Fatty Acids/blood , Rheumatic Fever/blood , Adolescent , Child , Child, Preschool , Humans , RecurrenceSubject(s)
Arteries/physiopathology , Hemodynamics , Lipid Metabolism , Obesity/physiopathology , Adolescent , Child , Child, Preschool , Elasticity , Female , Humans , Male , Obesity/metabolismSubject(s)
Blood Vessels/physiopathology , Hemodynamics , Obesity/physiopathology , Adolescent , Blood Circulation , Child , Elasticity , Female , Humans , MaleSubject(s)
Blood Glucose/analysis , Insulin/blood , Obesity/blood , Administration, Oral , Adolescent , Child , Fasting , Female , Glucose/administration & dosage , Glucose Tolerance Test , Humans , MaleSubject(s)
Lipoproteins, HDL/blood , Lipoproteins, LDL/blood , Lipoproteins, VLDL/blood , Obesity/blood , Adolescent , Child , Female , Humans , Hyperlipoproteinemia Type IV/etiology , MaleABSTRACT
In 81 children aged 0-18 years with normal body weight the serum pattern of fatty acids (FA) were determined by means of gas chromatography. The results show that of the 11 FA determined chromatographically, unsaturated and saturated fatty acids had differences in their distribution in the plasma. A certain regularity of these differences in favour of unsaturated fatty acids was observed. At the same time it was demonstrated that the mean values of unsaturated essential fatty acids (EUFA) increased with the age of a child. These results suggest that the plasma FA pattern may be a valuable supplementary source of information about lipid metabolism disturbances in children.
