ABSTRACT
In the clinic in 2000 - 2013 yrs of 42 injured persons with severe combined trauma of abdominal organs were treated, in 18 of them the method of a multi-staged treatment (damage control) with a short-term operative intervention on the first stage was applied, what permitted to lower postoperative lethality by 22.3%, and rate of purulent-septic complications--by 18.1%.
Subject(s)
Abdominal Cavity/surgery , Abdominal Injuries/surgery , Digestive System Surgical Procedures/methods , Postoperative Complications/prevention & control , Sepsis/pathology , Abdominal Injuries/mortality , Abdominal Injuries/therapy , Blood Pressure , Blood Transfusion, Autologous , Humans , Sepsis/etiology , Sepsis/mortality , Survival AnalysisABSTRACT
Influence of ischemia factors on the mechanisms of regeneration of colon tissue after imposition of colon anastomosis in an experiment were studied. In the group of animals with the model of arterial and venous ischemia of colon anastomosis by the methods of morphocytometry and immunomorphology used is studied change microcirculation in the place of anastomosis and also of fibroblasts morphofunctional activity in submucous layer of bowel and loud speaker of collagen I and the III type forming in different terms after the operation. It is shown that the most substantial factors, influencing on the process of intestinal anastomosis cicatrisation, are the phenomena an arterial ischemia and hypoxia of intestinal wall tissues, most expressed on 5-7 days, that in clinical terms requires application of the proper measures of prophylaxis of failure of intestinal wall sutures.
