ABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Middle Aged , Neuroendocrine Tumors/therapy , Adrenocorticotropic Hormone/analysis , Neuroectodermal Tumors, Primitive/therapy , Fludrocortisone/administration & dosageSubject(s)
ACTH Syndrome, Ectopic/etiology , Adrenocorticotropic Hormone/blood , Pancreatic Neoplasms/complications , ACTH Syndrome, Ectopic/therapy , Chromogranins/blood , Combined Modality Therapy , Embolization, Therapeutic , Everolimus/therapeutic use , Female , Fludrocortisone/therapeutic use , Humans , Hydrocortisone/blood , Ketoconazole/therapeutic use , Liver Neoplasms/secondary , Male , Middle Aged , Pancreatectomy , Pancreatic Neoplasms/blood , Pancreatic Neoplasms/drug therapy , Pancreatic Neoplasms/surgery , Peptides, Cyclic/therapeutic use , Phenylurea Compounds/therapeutic use , Quinolines/therapeutic use , Somatostatin/analogs & derivatives , Somatostatin/therapeutic use , Spironolactone/therapeutic use , Splenectomy , Sunitinib/therapeutic useABSTRACT
BACKGROUND: As nutritional status plays an important role in outcomes after surgery, this study evaluated the association between preoperative nutritional status (NS) and postoperative outcomes after major resection for lung cancer. METHODS: We identified 219 patients with a diagnosis of cancer who underwent pulmonary resection from 2010 to 2012. Preoperative NS was assessed by anthropometric and biological parameters, body mass index (BMI), and the Nutritional Risk Index (NRI). We stratified this population into 4 BMI groups: underweight, normal weight, overweight and obese and 4 NRI groups: well-nourished; mildly malnourished; moderately malnourished and severely malnourished. The outcomes measured were postoperative complications; 30-day postoperative mortality; hospital length of stay (LOS), overall survival (OS) and disease-free survival (DFS). We performed both unadjusted analysis and adjusted multivariable analysis, controlling for statistically significant variables. RESULTS: Mean BMI and NRI were, respectively, 26.5 ± 4.3 and 112.4 ± 3.3. There were no significant differences between BMI categories and resection type, pathological stage, or overall postoperative complications. By contrast, significant differences (p < 0.05) in postoperative complications were observed among the NRI groups. LOS was longer in underweight and/or malnourished patients. In terms of OS, we found no significant differences according to NRI and BMI; however, patients with underweight had significantly shorter DFS compared with patients with overweight and obesity (log-rank p-value = 0.001). CONCLUSION: NS as measured by the NRI is an independent predictor of the risk of postsurgical complications, regardless of clinicopathologic characteristics. NRI might therefore be an useful tool for identifying early-stage lung cancer patients at risk for postoperative complications.
Subject(s)
Carcinoma, Non-Small-Cell Lung/surgery , Lung Neoplasms/surgery , Nutrition Assessment , Nutritional Status , Postoperative Complications/epidemiology , Pulmonary Surgical Procedures/methods , Body Mass Index , Carcinoma, Non-Small-Cell Lung/diagnosis , Carcinoma, Non-Small-Cell Lung/mortality , Disease-Free Survival , Female , Follow-Up Studies , Humans , Incidence , Lung Neoplasms/diagnosis , Lung Neoplasms/mortality , Male , Middle Aged , Postoperative Period , Prognosis , Prospective Studies , Risk Factors , Spain/epidemiology , Survival Rate/trends , Time FactorsABSTRACT
El pasado día 2 de junio de 2011 el Institut Català dOncologia lHospitalet-Hospital Duran i Reynals acogió la primera Reunión de Trabajo Multidisciplinar en Oncogeriatría. La idea de la reunión, iniciativa de las Sociedades Médicas de Oncología Radioterápica, Geriatría y Gerontología, Cuidados Paliativos y Oncología Médica, fue la de iniciar una línea de trabajo conjunta entre las diferentes especialidades que intervienen habitualmente en el manejo del paciente de edad avanzada con patología oncológica. En este documento se recoge un resumen de los temas tratados(AU)
On 2nd of June 2011 the Institut Català d Oncologia lHospitalet--Hospital Duran i Reynals hosted the first Meeting of Multidisciplinary Work in Oncogeriatrics. The reason for the meeting, which follows on from an initiative of the Medical Societies of Radiotherapy, Oncology, Geriatrics and Gerontology and Palliative Care and Medical Oncology, was to initiate a joint line of work among the different specialties that generally take part in the handling of the elderly patient suffering from oncologic pathologies. This document summarises the different subjects covered during the Meeting(AU)
Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Geriatrics/education , Geriatrics/methods , Geriatrics/organization & administration , Neoplasms/epidemiology , Neoplasms/prevention & control , Consensus Development Conferences as Topic , Population Dynamics , Aging/physiology , Geriatric Assessment/methods , Geriatric Assessment/statistics & numerical data , Aged/statistics & numerical data , Health Services for the Aged/organization & administration , Health Services for the Aged/standards , Primary Health Care/trendsABSTRACT
On 2nd of June 2011 the Institut Català d' Oncologia l'Hospitalet--Hospital Duran i Reynals hosted the first Meeting of Multidisciplinary Work in Oncogeriatrics. The reason for the meeting, which follows on from an initiative of the Medical Societies of Radiotherapy, Oncology, Geriatrics and Gerontology and Palliative Care and Medical Oncology, was to initiate a joint line of work among the different specialties that generally take part in the handling of the elderly patient suffering from oncologic pathologies. This document summarises the different subjects covered during the Meeting.
