[Methodological approaches to studies of the functional state of lungs under conditions of intensive care]. / Metodicheskie podkhody k issledovaniiu funktsional'nogo sostoianiia legkikh v usloviiakh intensivnoi terapii.

Algorithms for automated processing of curves reflecting respiratory function of the lungs (pneumotachygram, psyrogram, transthoracic pressure) in grave patients were developed. A system of monitoring the parameters characterizing real time pulmonary ventilation, gas exchange, respiratory mechanics and aerodynamics was created. The described algorithms for calculating the curves of respiratory functions permit examination of pulmonary function during spontaneous respiration of a patient.

[Computerized monitoring of patients in the intensive care and resuscitation unit]. / Komp'iuternyi monitoring u bol'nykh v otdelenii intensivnoi terapii i reanimatsii.

Monitoring-computed systems were used during the therapeutic-diagnostic process at the resuscitation department of the All-Union Surgery Research Center in more than 1,000 patients who underwent operations on the heart, coronary arteries, bronchi, trachea, and esophagus. The main importance is attached to examination of the cardiorespiratory system. More than 90 derived parameters characterizing intracardiac hemodynamics, ventricular contractility, and oxygen transport are calculated according to special programs. For evaluation of the function of the lungs in an automated regimen, 32 parameters characterizing lung ventilation, gas exchange in the lungs, mechanism of respiration, and metabolism are calculated. Monitoring-computed care makes it possible to appraise the patient's condition in a given situation, the transient nature of changes in the physiological systems of the organism under the effect of therapy, and helps in choice of the optimal regimens of artificial lung ventilation and the methods of treatment. Computed appraisal of hemodynamics by means of the algorithm of the nearest point was found to be correct in 93% of cases. Storage of the results in the computer memory ensures an operative approach to information on any of the patients.

[A mathematical model of the biomechanics of respiration during artificial ventilation of the lungs]. / Matematicheskaia model' biomekhaniki dykhaniia pri iskusstvennoi ventiliatsii legkikh.

The authors review a mathematic model of the respiratory biomechanics during artificial lung ventilation, presenting a subsystem of the mathematic model of respiration designed at the All-Union Research Surgery Center of the USSR AMS and used in the medical information diagnostic system elaborated for the Department of Resuscitation and Intensive Care, provide differential equations of the mathematic model, the results of the numerical solution of the model and an example of using the model for solving a private problem of selecting an adequate mode of artificial lung ventilation.