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J Pharm Sci ; 67(5): 735-7, 1978 May.
Article in English | MEDLINE | ID: mdl-641827

ABSTRACT

Nine heterocyclic oxamic acid derivatives were synthesized and tested in the rat passive cutaneous anaphylactic assay as potential antiallergy agents. Some compounds also were tested for their effects on cholesterol-lipoprotein levels and for diuretic, antidiabetic, and antifertility activities in rats.


Subject(s)
Amino Acids/chemical synthesis , Oxamic Acid/chemical synthesis , Passive Cutaneous Anaphylaxis/drug effects , Animals , Furans/chemical synthesis , Furans/pharmacology , Oxamic Acid/analogs & derivatives , Oxamic Acid/pharmacology , Pyrroles/chemical synthesis , Pyrroles/pharmacology , Rats , Thiophenes/chemical synthesis , Thiophenes/pharmacology
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