1.
Fortschr Med
; 97(21): 1019-22, 1979 Jun 07.
Article
in German
| MEDLINE
| ID: mdl-437649
ABSTRACT
513 patients with chronic ulcers of the leg were treated with Trental 400 orally in addition to local therapy. Regarding the reduction of the symptoms: ulcer extension, coldness of the leg, paraesthesia, resting pain and improvement of walking distance, 215 patients were classified as considerably improved, 195 distinctly improved, 53 slightly improved and 44 unchanged. Four cases worsened, two cases could not be classified. The possibility of combining oral therapy with local treatment and surgical measures (skin-flaps) is shown in three case reports. Gastro-intestinal tolerance of Trental 400 was good, interactions with concomitantly administered drugs were not reported.
Subject(s)
Leg Ulcer/drug therapy , Pentoxifylline/therapeutic use , Theobromine/analogs & derivatives , Administration, Oral , Aged , Drug Therapy, Combination , Drug Tolerance , Female , Humans , Male , Middle Aged , Pentoxifylline/administration & dosage , Pentoxifylline/adverse effects , Time Factors
2.
Z Hautkr
; 49(18): 775-80, 1974 Sep 15.
Article
in German
| MEDLINE
| ID: mdl-4619253