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Vopr Med Khim ; 33(2): 93-6, 1987.
Article in Russian | MEDLINE | ID: mdl-3604151

ABSTRACT

Phospholipid composition was studied in liver mitochondrial membranes of rats consuming ethanol for a long time. A new phospholipid phosphatidyl ethanol was found in the membranes, which appears to be formed due to the action of endogenous phospholipase D. The phospholipase D activity was measured in mitochondria using direct evaluation. Administration of ethanol led to alteration in the ratio of mitochondrial phospholipids.


Subject(s)
Ethanol/toxicity , Intracellular Membranes/metabolism , Membrane Lipids/metabolism , Mitochondria, Liver/metabolism , Phospholipids/metabolism , Animals , Intracellular Membranes/drug effects , Male , Mitochondria, Liver/drug effects , Rats
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