ABSTRACT
Sixty nosocomial infections caused by Pseudomonas aeruginosa and Acinetobacter baumannii resistant to aminoglycosides, cephalosporins, quinolones, penicillins, monobactams, and imipenem were treated with colistin (one patient had two infections that are included as two different cases). The infections were pneumonia (33% of patients), urinary tract infection (20%), primary bloodstream infection (15%), central nervous system infection (8%), peritonitis (7%), catheter-related infection (7%), and otitis media (2%). A good outcome occurred for 35 patients (58%), and three patients died within the first 48 hours of treatment. The poorest results were observed in cases of pneumonia: only five (25%) of 20 had a good outcome. A good outcome occurred for four of five patients with central nervous system infections, although no intrathecal treatment was given. The main adverse effect of treatment was renal failure; 27% of patients with initially normal renal function had renal failure, and renal function worsened in 58% of patients with abnormal baseline creatinine levels. Colistin may be a good therapeutic option for the treatment of severe infections caused by multidrug-resistant P. aeruginosa and A. baumannii.
Subject(s)
Acinetobacter Infections/drug therapy , Anti-Bacterial Agents/therapeutic use , Colistin/therapeutic use , Cross Infection/drug therapy , Pseudomonas Infections/drug therapy , Adolescent , Adult , Aged , Aged, 80 and over , Anti-Bacterial Agents/adverse effects , Child , Child, Preschool , Colistin/adverse effects , Creatinine/blood , Drug Resistance, Multiple , Female , Humans , Injections, Intravenous , Male , Middle AgedABSTRACT
Los quistes epidermoides intratesticulares en la infancia.No existen datos clínicos específicos que nos orienten hacia un diagnóstico de certeza., siendo necesario el estudio histopatológico. Basados en el caso presentado y en la revisión de la literatura, se analizan aspectos clínicos y diagnósticos.Aunque el tratamiento quirúrgico más utilizado ha sido la orquiectomía.Se recomienda al igual que otros autores, la enucleación del quiste y la conservación del testículo
Subject(s)
Pediatrics , Epidermal Cyst/surgery , TestisABSTRACT
Los quistes epidermoides intratesticulares en la infancia.No existen datos clínicos específicos que nos orienten hacia un diagnóstico de certeza., siendo necesario el estudio histopatológico. Basados en el caso presentado y en la revisión de la literatura, se analizan aspectos clínicos y diagnósticos.Aunque el tratamiento quirúrgico más utilizado ha sido la orquiectomía.Se recomienda al igual que otros autores, la enucleación del quiste y la conservación del testículo