ABSTRACT
Tissue adhesives are gaining popularity in ophthalmology, as they could potentially reduce the complications associated with current surgical methods. An ideal tissue adhesive should have superior tensile strength, be non-toxic and anti-inflammatory, improve efficiency and be cost-effective. Both synthetic and biological glues are available. The primary synthetic glues include cyanoacrylate and the recently introduced polyethylene glycol (PEG) derivatives, while most biological glues are composed of fibrin. Cyanoacrylate has a high tensile strength, but rapidly polymerises upon contact with any fluid and has been associated with histotoxicity. Fibrin induces less toxic and inflammatory reactions, and its polymerisation time can be controlled. Tensile strength studies have shown that fibrin is not as strong as cyanoacrylate. While more research is needed, PEG variants currently appear to have the most promise. These glues are non-toxic, strong and time-effective. Through MEDLINE and internet searches, this paper presents a systematic review of the current applications of surgical adhesives to corneal, glaucoma, retinal, cataract and strabismus surgeries. Our review suggests that surgical adhesives have promise to reduce problems in current ophthalmic surgical procedures.
Subject(s)
Ophthalmologic Surgical Procedures/methods , Ophthalmology , Surgical Wound Dehiscence/prevention & control , Tissue Adhesives/pharmacology , Humans , Tensile Strength , Tissue Adhesives/chemistrySubject(s)
Blindness/etiology , Mucocele/complications , Orbital Diseases/complications , Paranasal Sinus Diseases/complications , Acute Disease , Adult , Blindness/physiopathology , Drainage , Female , Humans , Intraocular Pressure , Male , Middle Aged , Mucocele/diagnostic imaging , Mucocele/surgery , Orbital Diseases/diagnostic imaging , Orbital Diseases/surgery , Paranasal Sinus Diseases/diagnostic imaging , Paranasal Sinus Diseases/surgery , Rupture, Spontaneous , Tomography, X-Ray Computed , Visual Acuity/physiologyABSTRACT
A 14-year-old girl presented with a prolonged migraine visual aura of several weeks' duration. Symptoms gradually resolved over a 6-week period, with no recurrence of visual aura over a 20-month follow-up period. Although there is significant overlap between the features of stereotypical and persistent migraine auras, or "visual snow," the latter tend to be unformed and can occupy the entire visual field of both eyes. To our knowledge, this phenomenon has been reported only twice before in children. Recognition of its features will allow the pediatric ophthalmologist to differentiate persistent visual aura from visual hallucinations.
