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New Microbiol ; 24(4): 317-24, 2001 Oct.
Article in English | MEDLINE | ID: mdl-11718368

ABSTRACT

HCV genotyping by nucleic acid sequencing emphasizes the difficulties involved in carrying out a more precise determination of the infectant viral population, probably due in part to the finding of still unknown isolates. Signs of heterogeneity in the genotype composition of the viral quasi-species and its evolutionary dynamism over time, together with the role played by some, more potentially aggressive, isolates in causing hepatic damage, encourage a more in-depth study of such topics.


Subject(s)
Hepacivirus/genetics , Hepatitis C/epidemiology , Hepatitis C/virology , Alanine Transaminase/blood , Aspartate Aminotransferases/blood , DNA, Viral/analysis , Genetic Heterogeneity , Genotype , Hepacivirus/isolation & purification , Humans , Viral Load
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