ABSTRACT
This is a report of the initial (prevalence) screening for lung cancer in a population of 10.040 cigarette-smoking men 45 yr of age and older, recruited from metropolitan New York. All had posteroanterior and lateral chest roentgenograms, and approximately half the men, randomly chosen, also had sputum cytology (dual screen). Fifty-three confirmed lung cancers were found; 22 (40%) were AJCC Stage I, with 85% survival for 5 yr after resection, whereas only 2 of the remaining men with Stage II to III lung cancer lived longer than 3 yr. In the dual screen group, in which the 2 detection techniques could be compared, 6 Stage I lung cancers were detected by radiology alone, 7 by cytology alone, and only 1 by both techniques. All of the cases detected by cytology alone were squamous carcinomas, whereas two thirds of those detected by radiology alone were adenocarcinoma.
Subject(s)
Lung Neoplasms/epidemiology , Mass Screening/methods , Radiography, Thoracic , Sputum/cytology , Adenocarcinoma/epidemiology , Aged , Carcinoma/epidemiology , Carcinoma, Small Cell/epidemiology , Carcinoma, Squamous Cell/epidemiology , Humans , Lung Neoplasms/mortality , Male , Middle Aged , Time FactorsABSTRACT
Radiographs of 168 patients with non-small-cell lung cancer were reviewed. Following a negative initial examination, 102 tumors were detected during routine annual screening, while 66 were diagnosed during the interval between screenings. The cancers detected on routine yearly examination were smaller; the rate of resectability was higher, a larger number were Stage I, and survival was better. Within the routinely screened group, 65% had evidence of cancer on reviewing earlier radiographs; these patients tended to have earlier stages of cancer and a better survival rate.
