ABSTRACT
BACKGROUND: There is increasing evidence that tight blood glucose (BG) control improves outcomes in critically ill adults. Children show similar hyperglycaemic responses to surgery or critical illness. However it is not known whether tight control will benefit children given maturational differences and different disease spectrum. METHODS/DESIGN: The study is an randomised open trial with two parallel groups to assess whether, for children undergoing intensive care in the UK aged Subject(s)
Hyperglycemia/drug therapy
, Insulin/therapeutic use
, Intensive Care Units, Pediatric
, Patient Selection
, Adolescent
, Age Factors
, Child
, Child, Preschool
, Clinical Protocols
, Critical Illness/therapy
, Drug Monitoring
, England
, Humans
, Hyperglycemia/blood
, Hyperglycemia/epidemiology
, Hyperglycemia/etiology
, Infant
, Infant, Newborn
, Infusions, Intravenous
, Insulin/administration & dosage
, Postoperative Complications/blood
, Postoperative Complications/therapy
, Research Design
, Respiration, Artificial
, Treatment Outcome
, Vasoconstrictor Agents/therapeutic use
, Ventilator Weaning/statistics & numerical data
, Wounds and Injuries/blood
, Wounds and Injuries/therapy
